Upper neck papillary thyroid cancer (UPTC): A new proposed term for the composite of thyroglossal duct cyst-associated papillary thyroid cancer, pyramidal lobe papillary thyroid cancer, and Delphian node papillary thyroid cancer metastasis

2015 ◽  
Vol 126 (7) ◽  
pp. 1709-1714 ◽  
Author(s):  
Marica Zizic ◽  
William Faquin ◽  
Antonia E. Stephen ◽  
Dipti Kamani ◽  
Romy Nehme ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Cancer Metastasis ◽  
Thyroglossal Duct Cyst ◽  
Papillary Thyroid ◽  
Duct Cyst ◽  
Thyroglossal Duct ◽  
Pyramidal Lobe

scholarly journals Thyroglossal duct cyst papillary thyroid cancer – the state of the art

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Anna Maria Dabrowska ◽  
Jaroslaw Dudka
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Histopathological Examination ◽  
Malignant Neoplasm ◽  
Thyroglossal Duct Cyst ◽  
Benign Tumors ◽  
Papillary Thyroid ◽  
Duct Cyst ◽  
Thyroglossal Duct ◽  
Proper Diagnosis

Abstract Thyroglossal duct cyst is one of the most common congenital malformations in the neck area. The majority of cysts turn out to be benign tumors, however, 0.7-1.5 % of the remnants develop into carcinoma, with papillary thyroid cancer being the most frequent malignant neoplasm. The origin of the cancer has not been clearly established so far. Typically, thyroglossal duct cyst cancer is an enlarging flexible midline or slightly lateral neck mass, most often without other worrisome symptoms. The proper diagnosis can be difficult due to the rare prevalence of thyroglossal duct cyst papillary thyroid carcinoma, as well as a lack of strongly typical features distinguishing benign and malignant lesions before surgery. Thus, diagnosis is usually made postoperatively just after histopathological examination of a resected cyst. However, there are diagnostic procedures that should be considered before the surgery that may be helpful in making a proper diagnosis. These include fine-needle aspiration biopsy, computed tomography or magnetic resonance imaging. Moreover, there are some characteristics revealed through clinical and ultrasound examination that may suggest the presence of such cancer. While the Sistrunk procedure is often considered adequate, currently, there is no clear consensus about concurrent thyroidectomy or radioiodine therapy. In the article, we sum up the preoperative suggestive factors of cancer, as well as the proposed indications that can be helpful in deciding on the extent of surgery and further management.

scholarly journals SUN-618 An Unusual Case of Papillary Thyroid Cancer within a Thyroglossal Duct Cyst

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Janelle Yee ◽  
Maria Claudia Moscoso Cordero ◽  
Janice Gilden ◽  
Luis Borges Espinosa
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Unusual Case ◽  
Thyroglossal Duct Cyst ◽  
Papillary Thyroid ◽  
Duct Cyst ◽  
Thyroglossal Duct

scholarly journals Primary Papillary Thyroid Cancer of a Thyroglossal Duct Cyst

2019 ◽  
Vol 98 (3) ◽  
pp. 136-138 ◽  
Author(s):  
Jeffrey Liaw ◽  
Eric Cochran ◽  
Meghan N. Wilson
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Carcinoma ◽  
Thyroid Gland ◽  
Thyroid Carcinoma ◽  
Papillary Thyroid Cancer ◽  
Thyroglossal Duct Cyst ◽  
Important Case ◽  
Papillary Thyroid ◽  
Duct Cyst ◽  
Thyroglossal Duct

Papillary thyroid carcinoma in a thyroglossal duct cyst is very rare. We present the case of a teenage boy with a large thyroglossal duct cyst containing papillary thyroid carcinoma. There was no evidence of carcinoma within the thyroid gland, making this an important case of primary thyroglossal duct cyst carcinoma.

scholarly journals MON-443 SPECT/CT Localization of Incidental Diverticular Bleed After Radioiodine (i131) Therapy for Metastatic Thyroid Cancer

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Sejal B Doshi ◽  
Arash Kardan
Keyword(s):  
Thyroid Cancer ◽  
Sigmoid Colon ◽  
Papillary Thyroid Cancer ◽  
Thyroglossal Duct Cyst ◽  
Whole Body ◽  
Minor Bleeding ◽  
Papillary Thyroid ◽  
Duct Cyst ◽  
Thyroglossal Duct ◽  
Tissue Sodium

Abstract Background: Radioiodine therapy for patients with metastatic papillary and follicular thyroid cancer status post total thyroidectomy improves overall survival and is standard of care. Physiologic and pathologic biodistribution of I131 is dependent on tissue sodium iodine symporter expression with nonspecific radioiodine distribution seen secondary to physiologic routes of excretion. Clinical Case: Whole body scintigraphy (WBS) was performed seven days after I131 therapy in a 37-year-old male treated for metastatic papillary thyroid cancer with extension to a thyroglossal duct cyst at the time of surgery. His post-procedural course was uncomplicated with the exception of self-limited hematochezia six days after ablation. WBS images demonstrated a focus more superiorly in the neck concordant with metastatic thyroglossal duct cyst involvement. Activity was also present in the small and large bowel distribution reflecting normal routes of radioiodine excretion. WBS images depicted a discrete focus of radioiodine activity in the right lower quadrant, which SPECT/CT further localizes as activity in the sigmoid colon. Non-contrast CT images demonstrate an associated linear pattern of hyperdense hyperattenuation in the colonic lumen consistent with fresh blood. It is well established that the physiologic and pathologic biodistribution of I131 is dependent on tissue sodium-iodine symporter expression with additional distribution secondary to normal routes of excretion. Nonspecific radioiodine localization has been described at sites of inflammation secondary to vasodilation and increased vascular permeability resulting in leakage and accumulation in tissues. Sodium-iodine expression is found in many tissues, including salivary glands, lactating mammary glands, gastric mucosa, thymus, and small bowel; however, they are not expressed in the colon, nasopharyngeal mucosa, or orbital fibroblasts. I131 localization has been previously described within numerous body diverticula, such as Zenker’s and Meckel’s diverticula; however, radioiodine activity in association with an acute colonic diverticular bleed has not been reported. Conclusion: We propose that the isolated focus of radioiodine activity in the sigmoid colon associated with transient self-limited bleed could be either related to preexisting diverticulitis leading to I131 accumulation secondary to hyperemia, increased vascular capillary permeability, and subsequent aggravation of colonic mucosa resulting in a transient bleed or due to incidental nonspecific pooling of radioiodine in a colonic diverticulum resulting in secondary mucosal irritation with subsequent minor bleeding. To our knowledge this is the first reported case of SPECT/CT localization of radioiodine to an isolated colonic diverticular bleed in a patient status post I131 therapy for metastatic papillary thyroid cancer.

scholarly journals Coexisting Thyroglossal Duct Cyst with Papillary Thyroid Cancer: A Case Report and Literature Review

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Abdullah A. Alarfaj ◽  
Ahmed Zekri ◽  
Ibrahim Alyaeesh ◽  
Ahmed Alomairin ◽  
Abdulrahman Al Naim
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Needle Aspiration ◽  
Central Neck Dissection ◽  
Papillary Thyroid ◽  
Duct Cyst ◽  
Thyroglossal Duct ◽  
History Of ◽  
Detection And Diagnosis

Thyroglossal duct cysts (TGDCs) are common developmental anomalies in which the thyroglossal duct is not obliterated. Coexisting papillary thyroid cancer and TGDC are uncommon and should be investigated thoroughly to rule out TGDC carcinoma. We report a rare case of coexisting papillary thyroid cancer and TGDC in a 48-year-old man, who presented with a history of recurrent mild painful midline neck swelling, and ultrasound (US) revealed a TGDC that was subsequently managed conservatively. On follow-up after 1.6 years, a thyroid US and a fine-needle aspiration (FNA) biopsy were performed, which showed malignant papillary thyroid carcinoma. Total thyroidectomy, the Sistrunk procedure, and central neck dissection were implemented. After three days, the patient was discharged on 150 mg of levothyroxine. Follow-up was unremarkable with no complications. The authors would like to stress the importance of regular TGDC and thyroid gland follow-ups for early detection and diagnosis of thyroid malignancy via clinical examination and US.

scholarly journals Simultaneous Papillary Carcinoma in Thyroglossal Duct Cyst and Thyroid

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Gustavo Cancela e Penna ◽  
Henrique Gomes Mendes ◽  
Adele O. Kraft ◽  
Cynthia Koeppel Berenstein ◽  
Bernardo Fonseca ◽  
...  
Keyword(s):  
Papillary Carcinoma ◽  
Unusual Case ◽  
Incidental Finding ◽  
Thyroglossal Duct Cyst ◽  
Papillary Thyroid ◽  
Management Options ◽  
Current Management ◽  
Duct Cyst ◽  
Thyroglossal Duct ◽  
Sistrunk Procedure

Thyroglossal duct cyst (TDC) is a cystic expansion of a remnant of the thyroglossal duct tract. Carcinomas in the TDC are extremely rare and are usually an incidental finding after the Sistrunk procedure. In this report, an unusual case of a 36-year-old woman with concurrent papillary thyroid carcinoma arising in the TDC and on the thyroid gland is presented, followed by a discussion of the controversies surrounding the possible origins of a papillary carcinoma in the TDC, as well as the current management options.

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