Mycobacterial cervicofacial lymphadenitis in human immunodeficiency virus-infected individuals after antiretroviral therapy initiation

2015 ◽  
Vol 125 (11) ◽  
pp. 2498-2502 ◽  
Author(s):  
Yuria Ablanedo-Terrazas ◽  
Claudia Alvarado-de la Barrera ◽  
Matilde Ruiz-Cruz ◽  
Gustavo Reyes-Terán
Keyword(s):  
Human Immunodeficiency Virus ◽  
Antiretroviral Therapy ◽  
Therapy Initiation ◽  
Immunodeficiency Virus

scholarly journals Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome

2019 ◽  
Vol 70 (8) ◽  
pp. 1750-1753 ◽  
Author(s):  
Sara C Auld ◽  
Pholo Maenetje ◽  
Shruthi Ravimohan ◽  
Drew Weissman ◽  
Itai Ncube ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Cohort Study ◽  
Antiretroviral Therapy ◽  
Lung Function ◽  
Immune Reconstitution Inflammatory Syndrome ◽  
Immune Reconstitution ◽  
Research Attention ◽  
Therapy Initiation ◽  
Immunodeficiency Virus ◽  
Inflammatory Syndrome

Abstract End-organ impairment has received relatively little research attention as a possible manifestation of tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS). In this prospective cohort study, one-half of adults with human immunodeficiency virus and pulmonary tuberculosis experienced meaningful declines in lung function on antiretroviral therapy, suggesting a role for lung function in TB-IRIS definitions.

scholarly journals Depressive Symptoms and Engagement in Human Immunodeficiency Virus Care Following Antiretroviral Therapy Initiation

2018 ◽  
Vol 68 (3) ◽  
pp. 475-481 ◽  
Author(s):  
Angela M Bengtson ◽  
Brian W Pence ◽  
Matthew J Mimiaga ◽  
Bradley N Gaynes ◽  
Richard Moore ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Depressive Symptoms ◽  
Antiretroviral Therapy ◽  
Human Immunodeficiency Virus Care ◽  
Therapy Initiation ◽  
Immunodeficiency Virus

scholarly journals START or SMART? Timing of Antiretroviral Therapy Initiation and Cardiovascular Risk for People With Human Immunodeficiency Virus Infection

2016 ◽  
Vol 3 (1) ◽  
Author(s):  
Mark J. Siedner
Keyword(s):  
Human Immunodeficiency Virus ◽  
Antiretroviral Therapy ◽  
Published Data ◽  
Cvd Risk ◽  
Cd4 Counts ◽  
Therapy Initiation ◽  
Smart Study ◽  
Immunodeficiency Virus ◽  
Secondary Finding ◽  
Asymptomatic Hiv

Abstract The Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection (START) study has reinforced the benefits of early initiation of antiretroviral therapy (ART). However, a notable secondary finding from that study was that immediate initiation of ART did not prevent cardiovascular disease (CVD) events (0.17 vs 0.20 events/1000 person-years, P = .65). This result appears to contradict a body of evidence, most notably from the Strategies for Management of Antiretroviral Therapy (SMART) study, which reported a 70% increased hazard of cardiovascular events for those deferring or interrupting treatment. Thus, an important unresolved question is whether the timing of ART impacts CVD risk. In this review, published data on relationships between timing of ART and CVD risk are reviewed. The data support a role for ART in mitigating CVD risk at lower CD4 counts, but data also suggests that, among those initiating therapy early, ART alone appears to suboptimally mitigate CVD risk. Additional interventions to address CVD risk among human immunodeficiency virus-infected populations are likely to be needed.

scholarly journals CD4 Response Up to 5 Years After Combination Antiretroviral Therapy in Human Immunodeficiency Virus-Infected Patients in Latin America and the Caribbean

2015 ◽  
Vol 2 (2) ◽  
Author(s):  
Paula M. Luz ◽  
Pablo F. Belaunzarán-Zamudio ◽  
Brenda Crabtree-Ramírez ◽  
Yanink Caro-Vega ◽  
Daniel Hoces ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Latin America ◽  
Antiretroviral Therapy ◽  
Interquartile Range ◽  
Combination Antiretroviral Therapy ◽  
Cd4 Counts ◽  
Therapy Initiation ◽  
Immunodeficiency Virus ◽  
The Caribbean

We describe CD4 counts at 6-month intervals for 5 years after combination antiretroviral therapy initiation among 12 879 antiretroviral-naive human immunodeficiency virus-infected adults from Latin America and the Caribbean. Median CD4 counts increased from 154 cells/mm3 at baseline (interquartile range [IQR], 60–251) to 413 cells/mm3 (IQR, 234–598) by year 5.

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