The “Closed-Airway Sneeze”: An Unusual Cause of Laryngeal Fracture

2011 ◽  
Vol 121 (S4) ◽  
pp. S70-S70
Author(s):  
Daniel Faden ◽  
Alphi Elackattu ◽  
Michael Platt
Keyword(s):  
Closed Airway

The “Closed-Airway Sneeze”

2011 ◽  
Vol 145 (3) ◽  
pp. 515-516 ◽  
Author(s):  
Daniel Lawrence Faden ◽  
Alphi Elackatuu ◽  
Michael Platt
Keyword(s):  
Closed Airway

scholarly journals Tidal volume dependency of gas exchange in bronchoconstricted pig lungs

2007 ◽  
Vol 103 (1) ◽  
pp. 148-155 ◽  
Author(s):  
Axel Kleinsasser ◽  
I. Mark Olfert ◽  
Alex Loeckinger ◽  
G. Kim Prisk ◽  
Susan R. Hopkins ◽  
...  
Keyword(s):  
Tidal Volume ◽  
Dynamic Compliance ◽  
Inert Gas ◽  
High Tidal Volume ◽  
Pulmonary Resistance ◽  
Mechanically Ventilated ◽  
High Tidal Volume Ventilation ◽  
Volume Ventilation ◽  
Closed Airway

Independent of airway pressure, pulmonary resistance is known to fall with increasing tidal volumes, traditionally thought to result from radial traction on the airways. R. C. Anafi and T. A. Wilson ( J Appl Physiol 91: 1185–1192, 2001) recently presented a model of a single terminal airway that explains the tidal volume-associated fall in resistance with an additional mechanism pertinent to narrow airways: a stable, nearly closed airway that is challenged with an increase in tidal volume “pops open” to become a stable, well-opened airway, and thus resistance drops suddenly. To test this model in vivo, the effects of high (24 ml/kg) and low (9 ml/kg) tidal volume in bronchoconstricted lungs were assessed using 1) the multiple inert gas elimination technique (MIGET) and 2) a 15-breath multiple breath inert gas washout (MBW) technique in anesthetized pigs. With high tidal volume, ventilation/perfusion (V̇a/Q̇) mismatch was reduced (log SD Q̇ from 1.30 ± 0.11 to 1.09 ± 0.12, P < 0.05), and blood flow to lung units with V̇a/Q̇ ratios < 0.1 was significantly reduced (37 ± 4% of cardiac output to 7 ± 4%, P < 0.05). Dynamic compliance was twice as high during high-tidal-volume ventilation ( P = 0.002). MBW analysis revealed that, while heterogeneity of ventilation during bronchoconstriction was not significantly different between either low or high tidal volume (log SD V̇mbw = 1.39 ± 0.09 and 1.34 ± 0.02, respectively), preinspiratory lung volume (PILV) decreased by 42% with low-tidal-volume ventilation ( P < 0.05), whereas it did not change with high-tidal-volume ventilation. The higher PILV during high tidal volume is also consistent with Anafi and Wilson's model. In summary, the outcomes from MIGET, and to some extent the MBW, in our anesthetized and mechanically ventilated pigs are consistent with a bistable terminal airway model as proposed by Anafi and Wilson. However, our data do not allow exclusion of other mechanisms that may lead to improved ventilatory distribution when tidal volume is increased.

Mechanics of the human diaphragm during voluntary contraction: statics

1978 ◽  
Vol 44 (6) ◽  
pp. 829-839 ◽  
Author(s):  
A. Grassino ◽  
M. D. Goldman ◽  
J. Mead ◽  
T. A. Sears
Keyword(s):  
Volume Change ◽  
Lung Volume ◽  
Voluntary Contraction ◽  
Electromyographic Activity ◽  
Lung Volumes ◽  
Transdiaphragmatic Pressure ◽  
Rib Cage ◽  
The Relationship ◽  
Closed Airway

We related diaphragm electromyographic activity (Edi) to transdiaphragmatic pressure (Pdi) in man during graded inspiratory efforts. Estimates of rib cage and abdominal volume displacements were based on their anteroposterior (AP) diameter changes. The diaphragm was assumed to contract isometrically when subjects performed inspiratory efforts against a closed airway at specified abdominothoracic configurations, increasing Edi and Pdi while holding lung volume and rib case and abdominal AP diameters constant. The relationship between Pdi and Edi depends primarily on abdominothoracic configuration rather than lung volume. For equal increments in lung volume, the Pdi developed at constant Edi is four to eight times more sensitive to changes in abdominal than in rib cage AP diameter. We demonstrate an isofunctional state of the diaphragm at different lung volumes, when increases in lung volume and rib cage AP diameter are compensated for by slight decreases in abdominal AP diameter, resulting in a constant relationship between Edi and Pdi. We conclude that diaphragm shortening is reflected more directly in abdominal displacement than in lung volume change.

scholarly journals A case of vocal cord dysfunction with Takotsubo cardiomyopathy: is there a link?

2011 ◽  
Vol 1 (1) ◽  
pp. 8
Author(s):  
Xuan Ye ◽  
Sultana Aziza ◽  
Sean Gomes ◽  
William Lancashire ◽  
Paul S. Thomas
Keyword(s):  
Pulmonary Oedema ◽  
Vocal Cord ◽  
Takotsubo Cardiomyopathy ◽  
Vocal Cord Dysfunction ◽  
Haemodynamic Instability ◽  
Acute Pulmonary Oedema ◽  
Pathophysiological Mechanism ◽  
Pleural Effusions ◽  
Life Threatening ◽  
Closed Airway

Vocal cord dysfunction (VCD) is an underrecognised cause of dyspnoea as it is seldom life threatening, and also difficult to diagnose. However, there have been rare accounts of VCD, as in the present case, which have led to haemodynamic instability. This patient with VCD episodically developed acute pulmonary oedema, bilateral pleural effusions and Takotsubo cardiomyopathy, treated effectively with tracheostomy. This presentation hints at the possible existence of a common pathophysiological mechanism, namely, forced inspiration against a closed airway or sympathetic overstimulation.

Upper airway patency in the human infant: influence of airway pressure and posture

1980 ◽  
Vol 48 (3) ◽  
pp. 500-504 ◽  
Author(s):  
S. L. Wilson ◽  
B. T. Thach ◽  
R. T. Brouillette ◽  
Y. K. Abu-Osba
Keyword(s):  
Airway Pressure ◽  
Upper Airway ◽  
Surface Forces ◽  
Human Infant ◽  
Neck Flexion ◽  
Neck Extension ◽  
Airway Patency ◽  
Obstructive Apnea ◽  
Closing Pressure ◽  
Closed Airway

We have determined the influence of transmural pressure and neck posture on upper airway patency in infants after death. In natural resting postures, the airway was closed at transmural pressures not exceeding those normally seen during peak inspiratory airflow in the living infant, implying that a neuromuscular mechanism is necessary to maintain airway patency during life. Neck flexion raised closing pressure, making the airway more susceptible to collapse, whereas neck extension lowered closing pressure, making the airway more resistant to collapse. When the angle of flexion was kept constant, closing pressure was not significantly altered by turning the head or positioning the infant prone. Pressures above the corresponding closing pressure were required to reopen the closed airway, suggesting that the walls of the closed airway tended to adhere and implying that surface forces can impose an added load to airway-maintaining musculature during obstructive apnea in the living infant.

Reassessment of the interruption technique for measuring flow resistance in humans

1989 ◽  
Vol 67 (3) ◽  
pp. 933-937 ◽  
Author(s):  
G. Liistro ◽  
D. Stanescu ◽  
D. Rodenstein ◽  
C. Veriter
Keyword(s):  
Lung Disease ◽  
Healthy Subjects ◽  
Obstructive Lung Disease ◽  
Airflow Obstruction ◽  
Forced Expiratory Volume ◽  
Whole Body ◽  
Quiet Breathing ◽  
Flow Interruption ◽  
Whole Body Plethysmography ◽  
Closed Airway

We have previously produced evidence that, in patients with obstructive lung disease, compliance of extrathoracic airways is responsible for lack of mouth-to-alveolar pressure equilibration during respiratory efforts against a closed airway. The flow interruption method for measuring respiratory resistance (Rint) is potentially faced with the same problems. We reassessed the merits of the interruption technique by rendering the extrathoracic airways more rigid and by using a rapid shutter. We measured airway resistance (Raw) with whole body plethysmography during panting (at 2 Hz) and Rint during quiet breathing. Rint and Raw were expressed as specific airway (sGaw) and interruptive conductance (sGint), respectively. In nine healthy subjects (cheeks supported), sGint (0.140 +/- 0.050 s-1.cmH2O-1) was lower (P less than 0.02) than sGaw (0.182 +/- 0.043 s-1.cmH2O-1). By contrast, in 12 patients with severe obstructive lung disease (forced expiratory volume in 1 s/vital capacity = 41.0 +/- 19.8%), sGint (0.058 +/- 0.012 s-1.cmH2O-1) was higher (P less than 0.05) than sGaw (0.047 +/- 0.007 s-1.cmH2O-1), when the cheeks were supported. When the mouth floor was also supported, average values of sGaw (0.048 +/- 0.008 s-1.cmH2O-1) and sGint (0.049 +/- 0.014 s-1.cmH2O-1) became similar. In conclusion, we confirm previous findings in healthy subjects of higher values of Rint, with respect to Raw, probably because of differences in glottis opening between quiet breathing and panting. In airflow obstruction, supporting both the cheeks and the mouth floor decreased sGint, which became similar to sGaw.

scholarly journals Post-obstructive pulmonary edema from aspirated nuts

2017 ◽  
Vol 5 ◽  
pp. 2050313X1771739 ◽  
Author(s):  
Ahsan Bashir ◽  
Sabina Qureshi Ahmad ◽  
Joshua Silverman ◽  
Emily Concepcion ◽  
Haesoon Lee
Keyword(s):  
Foreign Body ◽  
Airway Obstruction ◽  
Pulmonary Edema ◽  
Early Recognition ◽  
Clinical History ◽  
Endoscopic Removal ◽  
Hemodynamic Changes ◽  
Mechanically Ventilated ◽  
Foreign Body Obstruction ◽  
Closed Airway

Objectives: Post-obstructive pulmonary edema is thought to occur from hemodynamic changes secondary to forced inspiration against the closed airway due to acute or chronic airway obstruction. We report a case of a 13 month-old boy who developed pulmonary edema from aspirated foreign body, nuts. Methods: He underwent emergency bronchoscopy to confirm the clinical diagnosis of aspirated nuts in the trachea and nuts were removed endoscopically. His trachea was then intubated and he was mechanically ventilated with oxygen. Results: He developed florid pulmonary edema early in the course with tracheal obstruction and during endoscopic removal of nuts. After removal of obstruction he was ventilated mechanically and pulmonary edema cleared rapidly. Conclusions: Aspirated nuts obstructing trachea can induce obstructive pulmonary edema. Early recognition of foreign body obstruction based on clinical history and its removal resolved pulmonary edema.

The Dangers of Sneezing: A Review of Injuries

2019 ◽  
Vol 33 (3) ◽  
pp. 331-337 ◽  
Author(s):  
Sean Setzen ◽  
Michael Platt
Keyword(s):  
Risk Factor ◽  
Upper Airway ◽  
Intrathoracic Pressure ◽  
Respiratory Compromise ◽  
Comprehensive Literature Review ◽  
Closed Glottis ◽  
Sudden Release ◽  
The Mean ◽  
Prior Trauma ◽  
Closed Airway

Background Sneezing is an almost universal daily phenomenon as a reflex to evacuate irritants from the nasal cavities. An autonomic-controlled buildup of intrathoracic pressure against a closed glottis followed by sudden release results in a burst of 1 kPa of air through the upper airway. Active intervention to limit a sneeze can be deleterious. Closure of the airway during a sneeze can result in over 20 times the airway pressures resulting in a variety of untoward events. This review summarizes all reported injuries that occurred as the result of a sneeze. Objective The objective of this review is to summarize the risks of closed-airway sneezing and determine if there are any trends which can help understand such injuries. Methods A comprehensive literature review was performed from 1948 to 2018 to identify all reports of sneeze-related injuries. Information was compiled from reports to gain insights into comorbidities and risk factors for sneeze injuries. Results There were 52 unique reports of sneeze-related injuries in the literature that were categorized into 6 areas of injury: intrathoracic, laryngeal/pharyngeal, ocular/orbital, intracranial/neurological, otologic, and other. The mean age of subjects who suffered a sneeze injury was 40 years old (range: 15–84 years), with 81% being male gender. Thirty percent had a risk factor for injury of prior trauma (5) or respiratory compromise (5). Conclusion A variety of injuries can occur during a sneeze, especially when a closed-airway sneeze is attempted, and high Valsalva pressure is transmitted to the other systems. Men are more at risk for these injuries with the majority occurring in patients with no known risk factor. When triggered, a sneeze should be allowed to proceed without intervention to prevent associated injuries.

Hypopharyngeal and neck cross-sectional changes monitored by inductive plethysmography

1990 ◽  
Vol 68 (6) ◽  
pp. 2649-2655 ◽  
Author(s):  
G. Liistro ◽  
D. Stanescu ◽  
G. Dooms ◽  
C. Veriter ◽  
G. Aubert-Tulkens ◽  
...  
Keyword(s):  
Computerized Tomography ◽  
Flow Rate ◽  
Significant Relationship ◽  
Sectional Area ◽  
Cross Sectional ◽  
Obstructive Apnea ◽  
Simultaneous Measurements ◽  
Mouth Pressure ◽  
Inductive Plethysmography ◽  
Closed Airway

We present a method to assess cross-sectional area (CSA) changes of the extrathoracic airways (EA) by using an inductive plethysmograph (IP) band placed around the upper part of the neck. Measurements of mouth pressure (Pm) (or flow rate, V) and neck CSA changes during respiratory efforts against a high (or infinite) resistance have shown a highly significant relationship between Pm changes (or V changes, respectively), reflecting CSA changes of the EA and CSA changes of the neck. Simultaneous measurements of CSA of the neck (by IP) and of EA (by computerized tomography) during sustained inspiratory and expiratory efforts against a closed airway showed a high correlation between changes in the former and latter structures. Changes in CSA of the neck were larger with positive than negative transmural pressures, in keeping with the known larger compliance of this airway during expiration. We found this method helpful to assess the behavior of the EA during obstructive apnea episodes, hypopneas, and snoring.

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