The use of lipid microtubes as a novel slow-release delivery system for laryngeal injection

2011 ◽  
Vol 121 (6) ◽  
pp. 1237-1243 ◽  
Author(s):  
Vasantha L. Kolachala ◽  
Eric E. Berg ◽  
Samantha Shams ◽  
Vivek Mukhatyar ◽  
Viranuj Sueblinvong ◽  
...  
Keyword(s):  
2018 ◽  
Vol 42 (19) ◽  
pp. 15538-15540 ◽  
Author(s):  
Kellie L. Weeks ◽  
Kyle R. Rutkowski ◽  
Arnold A. Morales Loyola ◽  
Gregory R. Boyce

The use of vitamin B6 derivatives as a chemical delivery system for volatile alcohols initiated by neutral water is described.


1998 ◽  
Vol 14 (3) ◽  
pp. 112-118 ◽  
Author(s):  
A. R. Hunter ◽  
E. E. J. Kirk ◽  
D. H. Robinson ◽  
T. B. Kardos
Keyword(s):  

2018 ◽  
Vol 69 (9) ◽  
pp. 2315-2317
Author(s):  
Ramona Daniela Pavaloiu ◽  
Fawzia Sha At ◽  
Corina Bubueanu ◽  
Georgeta Neagu ◽  
Adrian Albulescu ◽  
...  

The aim of this study was to develop a delivery system for polyphenols from an extract of Echinacea purpurea leaves, based on liposomes. Liposomes loaded with Echinacea purpurea were prepared and characterized in terms of entrapment efficiency, size, polydispersity index, stability and release behavior. Results showed good entrapment efficiency, small sizes, low polydispersity index and good stability over 90 days at 4oC. Also, the liposomal formulations presented reduced burst release and slow release of polyphenols compared with free extract. Therefore, liposomes offer a great potential in the development of drug delivery systems for polyphenols.


2013 ◽  
Vol 320 ◽  
pp. 495-504 ◽  
Author(s):  
Guo Jing Gou ◽  
Li E Dong ◽  
Feng Juan Bao ◽  
Zhi Yu Wang ◽  
Lin Jiao ◽  
...  

This paper reviewed our research progress in respects of th intercalation law of acetylsalicylic acid (ASP) with magnesium aluminate layered double hydroxide (LDH), the drug release mechanism and the tablet preparation effect of LDH-ASP system. We also discussed the propositions about the composite assembly rules, slow-release mechanism, and dosage form processing of the layered double hydroxide drug delivery system. Intercalation way and drug structure should be taken into consideration in assembly LDH-drugs system. The characteristic parameter of the composite LDH-drug reflected finely their loading efficiency and correlated definitely with drug release property. It had been found that the release rate and extent of intercalated drug was closely linked to the retarding status of LDH interlayer, which was dependent on the exchange mole ratio of n(drug) with n[HnPO4(3-n)-]. In addition, the grafting reaction and phase transformation degree of LDH layer was hinged on the acidity of solution. The slow-release function of the LDH-drug system could be improved significantly by compositing with dextran (DET). A sustained-release skeleton tablet was producted with DET-LDH-ASP drug delivery system and hydrophilic gel material HPMC, which could effectively overcome the "first pass effect" and " burst release problem" of LDH-drug oral agents. The slow-release effect of LDH drug delivery system could be ulteriorly improved in systemic circulation environments, attributed to the triple control of HPMC-DET-LDH, DET-LDH-drugs three-level supramolecular assembly and the special circulation in vivo. Key words: Layered double hydroxide, Supramolecular assembly, Release control, Slow controlled release drug delivery system


2010 ◽  
Vol 46 (8) ◽  
pp. 2587-2599 ◽  
Author(s):  
Baljit Singh ◽  
Nisha Sharma ◽  
Vikrant Sharma

2015 ◽  
Vol 31 (2) ◽  
pp. 223-230 ◽  
Author(s):  
Anindita Laha ◽  
Utkarsh Bhutani ◽  
Kishalay Mitra ◽  
Saptarshi Majumdar

1995 ◽  
Vol 115 (1) ◽  
pp. 87-93 ◽  
Author(s):  
Naohisa Katayama ◽  
Rika Tanaka ◽  
Yumiko Ohno ◽  
Chiaki Ueda ◽  
Takeshi Houjou ◽  
...  

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