Experimental determination of threshold dose in photodynamic therapy in normal rat liver

2007 ◽  
Vol 4 (6) ◽  
pp. 469-475 ◽  
Author(s):  
J Ferreira ◽  
L T Moriyama ◽  
C Kurachi ◽  
C Sibata ◽  
O Castro e Silva Jr. ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Experimental Determination ◽  
Rat Liver ◽  
Threshold Dose ◽  
Normal Rat

scholarly journals Experimental Determination of the Threshold Dose for Bifidogenic Activity of Dietary 1-Kestose in Rats

Foods ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 4 ◽  
Author(s):  
Ayako Watanabe ◽  
Yoshihiro Kadota ◽  
Hijiri Yokoyama ◽  
Shunya Tsuruda ◽  
Rina Kamio ◽  
...  
Keyword(s):  
Small Intestine ◽  
Experimental Determination ◽  
Gut Bacteria ◽  
Threshold Dose ◽  
Minimum Dose

1-Kestose is a non-digestible oligosaccharide consisting of glucose linked to two fructose units. While 1-kestose is not digested in the small intestine of mammals, it is fermented in the ceca and colon, where the growth of bifidobacteria is promoted. In the present study, we assessed the threshold dose of dietary 1-kestose that increased cecal bifidobacterial levels in rats. Rats were fed experimental diets containing 0% to 0.3% 1-kestose for four weeks. The levels of the genus Bifidobacterium and total gut bacteria were significantly increased in cecal samples of rats fed the 0.3% 1-kestose diet. Further, a significant correlation between the dose of 1-kestose and the levels of cecal Bifidobacterium and total gut bacteria was observed. The minimum dose of dietary 1-kestose to induce significant bifidogenic activity in rats was 0.3% by weight in the diet.

Interstitial Photodynamic Therapy in Normal Rat Liver

2010 ◽  
Author(s):  
Leandro M. Negreiros ◽  
Lilian T. Moriyama ◽  
Luis Gustavo Sabino ◽  
Clóvis Grecco ◽  
Emery C. Lins ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Rat Liver ◽  
Interstitial Photodynamic Therapy ◽  
Normal Rat

INTRACELLULAR DISTRIBUTION OF DESOXYRIBONUCLEO-DEPOLYMERASE IN NORMAL RAT LIVER, LIVER TUMOR, AND LIVER OF ANIMALS FED p-DIMETHYLAMINOAZOBENZENE

1954 ◽  
Vol 32 (1) ◽  
pp. 35-40 ◽  
Author(s):  
Gaston de Lamirande ◽  
Claude Allard ◽  
Antonio Cantero
Keyword(s):  
Rat Liver ◽  
Liver Tumor ◽  
Cell Activity ◽  
Mitotic Rate ◽  
Intracellular Distribution ◽  
Nuclear Fraction ◽  
Normal Rat ◽  
High Level ◽  
Soluble Material

The intracellular distribution of desoxyribonucleodepolymerase (DNase) has been investigated in the liver of animals fed p-dimethylaminoazobenzene (DAB), in liver freed from tumor, and in DAB induced tumor. The method is based on the determination of acid soluble material containing phosphorus, liberated by the action of the enzyme upon highly polymerized DNA. Results indicated that the nuclear DNase particularly accounts for a very low percentage of the whole cell activity in normal rat liver, whereas in nuclei of liver of DAB fed rats and of tumor the activity is increased to a high level. These facts suggest a possible correlation between the activity of DNase in the nuclear fraction and the mitotic rate of the tissue.

Determination of threshold dose with delta-aminolevulinic acid-induced porphyrins for effective photodynamic therapy

1994 ◽  
Author(s):  
Clemens Fritsch ◽  
Christoph Abels ◽  
Klaus Bolsen ◽  
Thomas Ruzicka ◽  
Alwin E. Goetz ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Aminolevulinic Acid ◽  
Threshold Dose

scholarly journals Reply to Comment on Watanabe, A.; Kadota, Y.; Yokoyama, H.; Tsuruda, S.; Kamio, R.; Tochio, T.; Shimomura, Y.; Kitaura, Y. Experimental Determination of the Threshold Dose for Bifidogenic Activity of Dietary 1-Kestose in Rats. Foods 2020, 9, 4

Foods ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 527
Author(s):  
Ayako Watanabe ◽  
Yoshihiro Kadota ◽  
Takumi Tochio ◽  
Yoshiharu Shimomura ◽  
Yasuyuki Kitaura
Keyword(s):  
Experimental Determination ◽  
Threshold Dose

The manuscript entitled “Comment on Experimental Determination of the Threshold Dose for Bifidogenic Activity of Dietary 1-Kestose in Rats” by Shen et al [...]

Determination of Threshold Dose of Photodynamic Therapy to Measure Superficial Necrosis

2009 ◽  
Vol 27 (1) ◽  
pp. 93-99 ◽  
Author(s):  
R.C.M.C. Ferraz ◽  
J. Ferreira ◽  
P.F.C. Menezes ◽  
C.H. Sibata ◽  
O. Castro e Silva ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Threshold Dose

scholarly journals Photodynamic therapy with porphyrin and phthalocyanine sensitisation: Quantitative studies in normal rat liver

1986 ◽  
Vol 54 (1) ◽  
pp. 43-52 ◽  
Author(s):  
S G Bown ◽  
C J Tralau ◽  
P D Coleridge Smith ◽  
D Akdemir ◽  
T J Wieman
Keyword(s):  
Photodynamic Therapy ◽  
Rat Liver ◽  
Quantitative Studies ◽  
Normal Rat

scholarly journals Comment on Experimental Determination of the Threshold Dose for Bifidogenic Activity of Dietary 1-Kestose in Rats. Foods 2020, 9, 4

Foods ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 519
Author(s):  
Yihao Shen ◽  
Yang Shi ◽  
Zhongke Sun
Keyword(s):  
Experimental Determination ◽  
Threshold Dose ◽  
Dose Effect ◽  
Bifidogenic Effect

Currently, our group is undertaking a program trying to evaluate the bifidogenic effect/activity of different prebiotics and their dose-effect relationships [...]

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