Cost-efficient selection of a marker panel in genetic studies

2011 ◽  
Vol 76 (1) ◽  
pp. 88-94 ◽  
Author(s):  
Jamie S. Sanderlin ◽  
Nicole Lazar ◽  
Michael J. Conroy ◽  
Jaxk Reeves
Keyword(s):  
Genetic Studies ◽  
Marker Panel ◽  
Cost Efficient ◽  
Efficient Selection ◽  
Selection Of

scholarly journals A groupwise mutual information metric for cost efficient selection of a suitable reference in cardiac computational atlas construction

2010 ◽  
Author(s):  
Corné Hoogendoorn ◽  
Tristan Whitmarsh ◽  
Nicolas Duchateau ◽  
Federico M. Sukno ◽  
Mathieu De Craene ◽  
...  
Keyword(s):  
Mutual Information ◽  
Atlas Construction ◽  
Information Metric ◽  
Cost Efficient ◽  
Suitable Reference ◽  
Efficient Selection ◽  
Selection Of

scholarly journals COST-EFFICIENT SELECTION OF STRESS TEST FOR LOW-RISK CHEST PAIN

2015 ◽  
Vol 65 (10) ◽  
pp. A122
Author(s):  
Joseph Gibbs ◽  
Carlos Calle-Muller ◽  
Matthew Cerasale ◽  
Tarun Jain ◽  
Sagger Mawri ◽  
...  
Keyword(s):  
Chest Pain ◽  
Stress Test ◽  
Low Risk ◽  
Cost Efficient ◽  
Efficient Selection ◽  
Selection Of

Characterization and cost-efficient selection of NoC topologies for general purpose CMPs

2013 ◽  
Author(s):  
Marta Ortín ◽  
Alexandra Ferrerón ◽  
Jorge Albericio ◽  
Darío Suárez ◽  
María Villarroya-Gaudó ◽  
...  
Keyword(s):  
General Purpose ◽  
Cost Efficient ◽  
Efficient Selection ◽  
Selection Of

scholarly journals Network Analysis Based on Unique Spectral Features Enables an Efficient Selection of Genomically Diverse Operational Isolation Units

2021 ◽  
Vol 9 (2) ◽  
pp. 416
Author(s):  
Charles Dumolin ◽  
Charlotte Peeters ◽  
Evelien De Canck ◽  
Nico Boon ◽  
Peter Vandamme
Keyword(s):  
Network Analysis ◽  
Hierarchical Clustering ◽  
Mass Spectra ◽  
Spectral Features ◽  
Maldi Tof ◽  
Maldi Tof Mass Spectra ◽  
Diversity Studies ◽  
Technical Sample ◽  
Efficient Selection ◽  
Selection Of

Culturomics-based bacterial diversity studies benefit from the implementation of MALDI-TOF MS to remove genomically redundant isolates from isolate collections. We previously introduced SPeDE, a novel tool designed to dereplicate spectral datasets at an infraspecific level into operational isolation units (OIUs) based on unique spectral features. However, biological and technical variation may result in methodology-induced differences in MALDI-TOF mass spectra and hence provoke the detection of genomically redundant OIUs. In the present study, we used three datasets to analyze to which extent hierarchical clustering and network analysis allowed to eliminate redundant OIUs obtained through biological and technical sample variation and to describe the diversity within a set of spectra obtained from 134 unknown soil isolates. Overall, network analysis based on unique spectral features in MALDI-TOF mass spectra enabled a superior selection of genomically diverse OIUs compared to hierarchical clustering analysis and provided a better understanding of the inter-OIU relationships.

Sign in / Sign up

Export Citation Format

Share Document