Reliability and Convergent Construct Validity of Quantitative Ultrasound for Synovitis, Meniscal Extrusion, and Osteophyte in Knee Osteoarthritis With MRI

2021 ◽  
Author(s):  
Win Min Oo ◽  
James M. Linklater ◽  
Kim L. Bennell ◽  
Matthew S. Daniel ◽  
Danielle Pryke ◽  
...  
Keyword(s):  
Construct Validity ◽  
Knee Osteoarthritis ◽  
Quantitative Ultrasound ◽  
Meniscal Extrusion ◽  
Convergent Construct Validity

scholarly journals Cross-cultural adaptation, reliability and validity of the Fremantle Knee Awareness Questionnaire in Italian subjects with painful knee osteoarthritis

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Marco Monticone ◽  
Cristiano Sconza ◽  
Igor Portoghese ◽  
Tomohiko Nishigami ◽  
Benedict M. Wand ◽  
...  
Keyword(s):  
Construct Validity ◽  
Knee Osteoarthritis ◽  
Pain Intensity ◽  
Internal Consistency ◽  
Structural Validity ◽  
Retest Reliability ◽  
Knee Oa ◽  
Pain Catastrophising ◽  
Test Retest Reliability ◽  
Painful Knee

Abstract Background and aim Growing attention is being given to utilising physical function measures to better understand and manage knee osteoarthritis (OA). The Fremantle Knee Awareness Questionnaire (FreKAQ), a self-reported measure of body-perception specific to the knee, has never been validated in Italian patients. The aims of this study were to culturally adapt and validate the Italian version of the FreKAQ (FreKAQ-I), to allow for its use with Italian-speaking patients with painful knee OA. Methods The FreKAQ-I was developed by means of forward–backward translation, a final review by an expert committee and a test of the pre-final version to evaluate its comprehensibility. The psychometric testing included: internal structural validity by Rasch analysis; construct validity by assessing hypotheses of FreKAQ correlations with the knee injury and osteoarthritis outcome score (KOOS), a pain intensity numerical rating scale (PI-NRS), the pain catastrophising scale (PCS), and the Hospital anxiety and depression score (HADS) (Pearson’s correlations); known-group validity by evaluating the ability of FreKAQ scores to discriminate between two groups of participants with different clinical profiles (Mann–Whitney U test); reliability by internal consistency (Cronbach’s alpha) and test–retest reliability (intraclass correlation coefficient, ICC2.1); and measurement error by calculating the minimum detectable change (MDC). Results It took one month to develop a consensus-based version of the FreKAQ-I. The questionnaire was administered to 102 subjects with painful knee OA and was well accepted. Internal structural validity confirmed the substantial unidimensionality of the FreKAQ-I: variance explained was 53.3%, the unexplained variance in the first contrast showed an eigenvalue of 1.8, and no local dependence was detected. Construct validity was good as all of the hypotheses were met; correlations: KOOS (rho = 0.38–0.51), PI-NRS (rho = 0.35–0.37), PCS (rho = 0.47) and HADS (Anxiety rho = 0.36; Depression rho = 0.43). Regarding known-groups validity, FreKAQ scores were significantly different between groups of participants demonstrating high and low levels of pain intensity, pain catastrophising, anxiety, depression and the four KOOS subscales (p ≤ 0.004). Internal consistency was acceptable (α = 0.74) and test–retest reliability was excellent (ICC = 0.92, CI 0.87–0.94). The MDC95 was 5.22 scale points. Conclusion The FreKAQ-I is unidimensional, reliable and valid in Italian patients with painful knee OA. Its use is recommended for clinical and research purposes.

scholarly journals Translation, cross-cultural adaptation and validation of the English Lequesne Algofunctional index in to Bengali

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Tarek Mahmood ◽  
Minhaj Rahim Choudhury ◽  
Md Nazrul Islam ◽  
Syed Atiqul Haq ◽  
Md Abu Shahin ◽  
...  
Keyword(s):  
Construct Validity ◽  
Knee Osteoarthritis ◽  
Correlation Coefficient ◽  
Internal Consistency ◽  
Cultural Adaptation ◽  
Convergent Validity ◽  
Divergent Validity ◽  
Retest Reliability ◽  
Knee Oa ◽  
Test Retest Reliability

Abstract Background This study was focused on translation and cultural adaptation of the English Lequesne Algofunctional index (LAI) into Bengali for patients with primary knee osteoarthritis (OA) and testing reliability and validity of the Bengali version of the LAI. Methods This study was carried out in the Department of Rheumatology, BSM Medical University, Dhaka, Bangladesh. Using the forward–backward method the English LAI was translated into Bengali including cultural adaptation. For pretesting, A sample of 40 patients with primary knee osteoarthritis were screened using the Bengali version of LAI. Following the pretest, 130 consecutive patients with symptomatic knee OA completed the interviewer administered Bengali LAI, the validated Bengali version of SF-36, Visual Analogue Scale for Pain, Distance Walked and Activities of Daily Living. For the retest 60 randomly selected patients from the cohort were administered the Bengali LAI 7 days later. An item by item analysis was performed. Internal consistency was assessed by Cronbach’s alpha, test–retest reliability by intraclass correlation coefficient (ICC) and Kappa coefficient, construct validity was measured using the Spearman rank correlation coefficient. Results It took 3.25 ± 0.71 min to complete the Bengali LAI and the mean score was 9.23 ± 4.58. For the Bengali LAI Cronbach’s alpha score was 0.88, test–retest reliability assessed by ICC was 0.97. For construct validity, excellent convergent validity was achieved (ρ = 0.93) but the divergent validity was moderate (ρ = 0.43). Conclusions The Bengali LAI showed excellent convergent validity, internal consistency and test–retest reliability, only the divergent validity was moderate. So, the Bengali LAI can be applied as a HRQoL assessment tool for primary knee OA patients.

scholarly journals ANALYTICAL CONSIDERATIONS OF DEVELOPING A PHENOTYPIC AGING MEASURE: THE CONCEPTUAL FRAMEWORK MUST COME FIRST!

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S579-S580
Author(s):  
Michelle Shardell ◽  
Michelle Shardell ◽  
Pei-Lun Kuo ◽  
Jennifer Schrack ◽  
Eleanor M Simonsick ◽  
...  
Keyword(s):  
Construct Validity ◽  
Latent Variable ◽  
Structural Model ◽  
Chronological Age ◽  
Model Framework ◽  
Domain Specific ◽  
Genes And Environment ◽  
Convergent Construct Validity ◽  
Baltimore Longitudinal Study ◽  
Using Data

Abstract We propose a latent structural model framework where phenotypic aging is a latent variable influenced by chronological age, genes and environment. Within this framework, phenotypic age influences aging-related outcomes and is reflected by latent domains of aging (body composition, energetics, homeostasis, and neural functioning) reflected by biomarkers. First, we validate the framework by selecting age-associated domain-specific biomarkers and assessing internal consistency and convergent construct validity (Cronbach’s alpha). Using data from the Baltimore Longitudinal Study of Aging, within-domain Cronbach’s alphas ranged from 0.80 to 0.92, supporting convergent construct validity. Second, we evaluate two broad methods for combining biomarkers into one phenotypic age measure customized to different objectives: 1) confirmatory factor analysis of chronological age-adjusted biomarkers to create a measure to identify pleiotropic genetic and environmental mechanisms, and 2) machine-learning methods to create a measure optimizing predictive and concurrent criterion validity. This framework will enable evaluation of candidate biological mechanisms of aging.

scholarly journals Factors associated with longitudinal change of meniscal extrusion in overweight women without clinical signs of knee osteoarthritis

2019 ◽  
Vol 27 ◽  
pp. S337-S338
Author(s):  
J.A. van der Voet ◽  
D. Wesselius ◽  
D. Vroegindeweij ◽  
E.H. Oei ◽  
S.M. Bierma - Zeinstra ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Clinical Signs ◽  
Longitudinal Change ◽  
Meniscal Extrusion ◽  
Overweight Women ◽  
Factors Associated

scholarly journals Do body mass index and knee osteoarthritis status affect meniscal extrusion and size?

2019 ◽  
Vol 27 ◽  
pp. S368 ◽  
Author(s):  
I.P. Munugoda ◽  
D.A. Aitken ◽  
W. Wirth ◽  
F. Eckstein
Keyword(s):  
Body Mass Index ◽  
Knee Osteoarthritis ◽  
Body Mass ◽  
Meniscal Extrusion

scholarly journals Questionnaire measuring patient participation in health care: Scale development and psychometric evaluation

2020 ◽  
Vol 19 (7) ◽  
pp. 600-608
Author(s):  
Selina Kikkenborg Berg ◽  
Jane Færch ◽  
Pernille Fevejle Cromhout ◽  
Marianne Tewes ◽  
Preben Ulrich Pedersen ◽  
...  
Keyword(s):  
Health Care ◽  
Factor Analysis ◽  
Construct Validity ◽  
Factor Structure ◽  
Internal Consistency ◽  
Patient Participation ◽  
Cardiac Disease ◽  
Psychometric Evaluation ◽  
Mixed Group ◽  
Convergent Construct Validity

Background: Patient participation in treatment and care is often encouraged and is desirable because of its proven positive impact on treatment, quality of care and patient safety. Aims: To develop an instrument to measure patient participation in health care and to investigate the measurement properties of the Patient Participation Questionnaire (PPQ). Methods: A literature review was conducted to develop a model of patient participation. The PPQ was constructed consisting of 17 items organized into four subscales. Psychometric evaluation of factor structure, convergent construct validity by hypothesis testing and analyses of internal consistency using Cronbach’s alpha were performed on data from a hospitalised mixed group of patients with cardiac disease, pulmonary disease and cancer ( N=378 patients). Results: Confirmatory factor analysis did not show a clear model fit, which is why an exploratory factor analysis was performed, suggesting a different four subscale structure consisting of a total of 16 items. The four subscales were labelled Shared decision power, Adapted and individualized knowledge, Collaboration and Human approach. There were strong ceiling effects on all items. Analysis of convergent construct validity showed a moderate correlation (0.59) between the PPQ and another instrument measuring patient participation. Internal consistency for the total PPQ score was high: 0.89. Conclusion: In a mixed group of patients with cardiac disease, pulmonary disease and cancer, the PPQ showed promising psychometric properties in terms of factor structure, convergent construct validity and internal consistency. The PPQ may be used to shed light on the experience of patient participation and guide quality improvements.

Cross-cultural adaptation, validity, and reliability of the Neck OutcOme Score (NOOS-Ar) among the Saudi Arabian populace

2020 ◽  
pp. 1-10
Author(s):  
Mazen Alqahtani
Keyword(s):  
Construct Validity ◽  
Psychometric Properties ◽  
Internal Consistency ◽  
Minimal Detectable Change ◽  
Detectable Change ◽  
Everyday Activity ◽  
Retest Reliability ◽  
Outcome Score ◽  
Convergent Construct Validity ◽  
Test Retest Reliability

BACKGROUND: To date the Neck OutcOme Score (NOOS) was not cross-culturally adapted, validated or available in the Arabic language, although it was available in other languages. OBJECTIVE: To translate and cross-culturally adapt the Arabic version of the Neck OutcOme Score (NOOS-Ar) and study its psychometric properties. METHODS: A sample of 146 subjects with chronic neck pain filled in the NOOS-Ar questionnaire to determine the Cronbach’s alpha (α) for internal consistency, test-retest reliability by intraclass correlation coefficients(2,1) [ICC(2,1)], inter-item correlation, measurement error by coefficient of variance and minimal detectable change, ceiling and floor effects, convergent construct validity with visual analog scale (VAS) by Spearman’s rank correlation coefficient (ρ) and factor analysis to calculate and determine its psychometric properties. RESULTS: Excellent internal consistency (Cronbach’s α> 0.9) and test-retest reliability [ICC(2,1)> 0.9] were observed in NOOS-Ar. None of the five subscales of the NOOS-Ar showed a floor or ceiling effect. The coefficient of variance was generally high, but the minimal detectable change was within the acceptable range (< 30%). The ‘everyday activity and pain’ and ‘symptoms’ subscales of the NOOS-Ar, showed a moderate correlation with VAS. CONCLUSION: The NOOS-Ar is highly reliable and has a moderate to good degree of convergent construct validity with VAS with no floor or ceiling effects.

scholarly journals Baseline meniscal extrusion associated with incident knee osteoarthritis after 30 months in overweight and obese women

2017 ◽  
Vol 25 (8) ◽  
pp. 1299-1303 ◽  
Author(s):  
J.A. van der Voet ◽  
J. Runhaar ◽  
P. van der Plas ◽  
D. Vroegindeweij ◽  
E.H. Oei ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Obese Women ◽  
Meniscal Extrusion

scholarly journals Comparison of Diagnostic Performance of Semi-Quantitative Knee Ultrasound and Knee Radiography with MRI: Oulu Knee Osteoarthritis Study

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Jana Podlipská ◽  
Ali Guermazi ◽  
Petri Lehenkari ◽  
Jaakko Niinimäki ◽  
Frank W. Roemer ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Knee Osteoarthritis ◽  
Diagnostic Performance ◽  
Structural Changes ◽  
Morphological Changes ◽  
Cost Effective ◽  
Conventional Radiography ◽  
Joint Space ◽  
Meniscal Extrusion ◽  
Knee Oa

Abstract Osteoarthritis (OA) is a common degenerative musculoskeletal disease highly prevalent in aging societies worldwide. Traditionally, knee OA is diagnosed using conventional radiography. However, structural changes of articular cartilage or menisci cannot be directly evaluated using this method. On the other hand, ultrasound is a promising tool able to provide direct information on soft tissue degeneration. The aim of our study was to systematically determine the site-specific diagnostic performance of semi-quantitative ultrasound grading of knee femoral articular cartilage, osteophytes and meniscal extrusion, and of radiographic assessment of joint space narrowing and osteophytes, using MRI as a reference standard. Eighty asymptomatic and 79 symptomatic subjects with mean age of 57.7 years were included in the study. Ultrasound performed best in the assessment of femoral medial and lateral osteophytes, and medial meniscal extrusion. In comparison to radiography, ultrasound performed better or at least equally well in identification of tibio-femoral osteophytes, medial meniscal extrusion and medial femoral cartilage morphological degeneration. Ultrasound provides relevant additional diagnostic information on tissue-specific morphological changes not depicted by conventional radiography. Consequently, the use of ultrasound as a complementary imaging tool along with radiography may enable more accurate and cost-effective diagnostics of knee osteoarthritis at the primary healthcare level.

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