scholarly journals Evaluation of Common Carotid Stiffness via Echo Tracking in Hypertensive Patients Complicated by Acute Aortic Dissection

2020 ◽  
Author(s):  
Wenhui Gu ◽  
Juan Wu ◽  
Yongkai Pei ◽  
Jiamei Ji ◽  
Haibo Wu ◽  
...  
Keyword(s):  
Aortic Dissection ◽  
Acute Aortic Dissection ◽  
Hypertensive Patients ◽  
Carotid Stiffness ◽  
Echo Tracking

The coexistence of acute aortic dissection with autosomal dominant polycystic kidney disease - description of two hypertensive patients

2004 ◽  
Vol 13 (5) ◽  
pp. 283-286 ◽  
Author(s):  
Mariola Pe¸czkowska ◽  
Andrzej Januszewicz ◽  
Władysław Grzeszczak ◽  
Dariusz Moczulski ◽  
Hanna Janaszek-sitkowska ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Aortic Dissection ◽  
Polycystic Kidney Disease ◽  
Autosomal Dominant ◽  
Acute Aortic Dissection ◽  
Polycystic Kidney ◽  
Hypertensive Patients ◽  
Autosomal Dominant Polycystic Kidney

scholarly journals Impact of hypertension on short- and long-term survival of Patients Who Underwent Emergency Surgery for Type A Acute Aortic Dissection

2020 ◽  
Author(s):  
Dongjin Wang ◽  
Zhigang Wang ◽  
Tao Chen ◽  
Min Ge ◽  
Cheng Chen ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Aortic Dissection ◽  
Clinical Characteristics ◽  
Acute Aortic Dissection ◽  
Term Survival ◽  
Hypertensive Patients ◽  
Long Term Survival ◽  
Propensity Scoring ◽  
Significant Difference

Abstract ObjectiveTo explore the clinical characteristics and prognosis of patients with hypertension underwent emergency surgery for type A acute aortic dissection (TA-AAD).MethodsThe present study enrolled 712 consecutive patients diagnosed with TA-AAD who were admitted to our hospital between January 2014 to December 2018. All patients accepted aortic repair surgery during hospitalization. The cohort was separated into two groups based on if they were diagnosed with hypertension upon administration. Before analyzing the short-term outcomes, baseline characteristics were matched for propensity scores. Patients’ clinical characteristics were compared and analyzed before and after propensity scoring. To identify predictors for long-term mortality rate, Kaplan-Meier survival estimation and Cox proportional hazard analysis were performed.ResultsThe 492 patients (69.1% of all patients in the cohort) included in the hypertensive group were generally older and heavier than patients in the non-hypertensive group. Between two groups, preoperative leukocyte count and serum creatinine level were found significant different (P < 0.05). After propensity scoring, 128 pairs (256 patients) were successfully matched. Our analysis showed that there was no significant difference of ventilation duration, 30-day mortality rate, intensive care unit (ICU) stay time and hospitalization time between these patients. However, our observation from surgeries suggested that hypertensive patients presented with less intraoperative aortic valve involvement.There was a significant difference in long-term survival rate (P=0.037) between two groups and Cox regression analysis demonstrated that hypertension was an independent risk factor (hazard ratio [HR], 2.290; 95% confidence interval [CI], 1.013-5.178; P=0.046).Conclusions Our data suggested that TA-AAD patients complicated with hypertension were generally older and heavier compared to non-hypertensive patients. The hypertension diagnosed upon hospital administration was an independent risk factors for long-term survival in TA-AAD patients but did not influence the 30-day mortality rate.

scholarly journals Predictors for the development of preoperative oxygenation impairment in acute aortic dissection in hypertensive patients

2020 ◽  
Author(s):  
Xuemin Zhao ◽  
Mengjun Bie
Keyword(s):  
Body Temperature ◽  
Aortic Dissection ◽  
Acute Aortic Dissection ◽  
Linear Regression Analysis ◽  
Oxygenation Index ◽  
Operating Characteristics ◽  
Laboratory Findings ◽  
Hypertensive Patients ◽  
Serum Crp ◽  
Oxygenation Impairment

Abstract Background Acute aortic dissection (AAD) is an acute life-threatening cardiovascular disease, which is frequently complicated with oxygenation impairment (OI). We aim to investigate predictors of the development of OI in the patients with AAD.Methods We retrospectively collected clinical data of AAD in hypertensive patients from July 2012 to March 2020. The patients included in this study were divided into OI (+) group (oxygenation index≤200) and OI (-) group (oxygenation index>200). Both groups were compared according to demographic and clinical characteristics, and laboratory findings. Characteristics of hypertension in the patients with AAD were described. Predictors for the development of OI were assessed. And cutoff values were determined by receiver operating characteristics (ROC) curve.Results A total of 208 patients were included in this study and the incidence of OI was 32.2%. In OI (+) group, patients had significantly higher peak body temperature (37.85±0.60 vs 37.64±0.44℃, P= .005), higher levels of CRP (42.70±28.27 vs 13.90±18.70mg/L, P= .000) and procalcitonin (1.07±3.92 vs 0.31±0.77ug/L, P= .027), and lower levels of albumin (34.21±5.65 vs 37.73±4.70g/L, P= .000). Spearman’s rank correlation test showed that the minimum oxygenation index was positively correlated with albumin, and was negatively correlated with the peak body temperature, serum CRP, procalcitonin, BNP and troponin. The stepwise multiple linear regression analysis showed that the peak body temperature, serum CRP and albumin were independently associated with development of OI. An optimal cutoff value for CRP for predicting OI was ≥9.20 mg/L, with a sensitivity of 91.0% and a specificity of 61.0%.Conclusions The peak body temperature, serum CRP and albumin were independent predictors of OI development in the patients with AAD. The serum CRP on admission≥9.20 mg/L might be a valuable and reliable indicator in predicting the development of OI.

scholarly journals Predictors for the development of preoperative oxygenation impairment in acute aortic dissection in hypertensive patients

2020 ◽  
Author(s):  
Xuemin Zhao ◽  
Mengjun Bie
Keyword(s):  
Body Temperature ◽  
Aortic Dissection ◽  
Acute Aortic Dissection ◽  
Linear Regression Analysis ◽  
Oxygenation Index ◽  
Operating Characteristics ◽  
Laboratory Findings ◽  
Hypertensive Patients ◽  
Serum Crp ◽  
Oxygenation Impairment

Abstract Background Acute aortic dissection (AAD) is an acute life-threatening cardiovascular disease, which is frequently complicated with oxygenation impairment (OI). Objective We aim to investigate predictors of the development of OI in the patients with AAD. Methods We retrospectively collected clinical data of AAD in hypertensive patients from July 2012 to March 2020. The patients included in this study were divided into OI (+) group (oxygenation index ≤ 200) and OI (-) group (oxygenation index > 200). Both groups were compared according to demographic and clinical characteristics, and laboratory findings. Characteristics of hypertension in the patients with AAD were described. Predictors for the development of OI were assessed. And cutoff values were determined by receiver operating characteristics (ROC) curve. Results A total of 208 patients were included in this study and the incidence of OI was 32.2%. In OI (+) group, patients had significantly higher peak body temperature (37.85 ± 0.60 vs 37.64 ± 0.44℃, P = .005), higher levels of CRP (42.70 ± 28.27 vs 13.90 ± 18.70 mg/L, P = .000) and procalcitonin (1.07 ± 3.92 vs 0.31 ± 0.77ug/L, P = .027), and lower levels of albumin (34.21 ± 5.65 vs 37.73 ± 4.70 g/L, P = .000). Spearman’s rank correlation test showed that the minimum oxygenation index was positively correlated with albumin, and was negatively correlated with the peak body temperature, serum CRP, procalcitonin, BNP and troponin. The stepwise multiple linear regression analysis showed that the peak body temperature, serum CRP and albumin were independently associated with development of OI. An optimal cutoff value for CRP for predicting OI was ≥ 9.20 mg/L, with a sensitivity of 91.0% and a specificity of 61.0%. Conclusions The peak body temperature, serum CRP and albumin were independent predictors of OI development in the patients with AAD. The serum CRP on admission ≥ 9.20 mg/L might be a valuable and reliable indicator in predicting the development of OI.

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