scholarly journals Three‐Dimensional Subharmonic Aided Pressure Estimation for Assessing Arterial Plaques in a Rabbit Model

2018 ◽  
Vol 38 (7) ◽  
pp. 1865-1873 ◽  
Author(s):  
Kibo Nam ◽  
Ji‐Bin Liu ◽  
John R. Eisenbrey ◽  
Maria Stanczak ◽  
Priscilla Machado ◽  
...  
Keyword(s):  
Rabbit Model ◽  
Three Dimensional ◽  
Pressure Estimation ◽  
Arterial Plaques

scholarly journals Implant-based three-dimensional superimposition of the growing mandible in a rabbit model

2015 ◽  
Vol 38 (5) ◽  
pp. 546-552 ◽  
Author(s):  
Andrew L. Parton ◽  
Warwick J. Duncan ◽  
Marcelo E. Oliveira ◽  
Oscar Key ◽  
Mauro Farella
Keyword(s):  
Rabbit Model ◽  
Three Dimensional

A Novel Animal Model for Three-Dimensional Horizontal and Vertical Bone Regeneration Using Osseous Shell Technique: A Pre-clinical In-Vivo Study in Rabbits

2021 ◽  
Author(s):  
Mohammad Kamal ◽  
Sara Al-Obaidly ◽  
Bernd Lethaus ◽  
Alexander K. Bartella
Keyword(s):  
Animal Model ◽  
Bone Regeneration ◽  
Bone Grafting ◽  
Rabbit Model ◽  
Three Dimensional ◽  
Materials Testing ◽  
Bone Augmentation ◽  
Mandibular Ramus ◽  
Skeletal Defects

Abstract Background: Bone grafting is commonly used for reconstructing skeletal defects in the craniofacial region. Several bone augmentation models were developed to optimize bone regeneration in both vertical and horizontal dimesions. Aim: The aim of this study was to develop a surgical animal model for establishing a three-dimensional (3D) grafting environment in the animal's mandibular ramus for horizontal and vertical bone regeneration using osseous shell technique, as in human patients. Materials and methods: Initial osteological and imaging survey were performed on a postmortem skull of a New Zealand White (NZW) rabbit skull, Oryctolagus cuniculus, for feasibility assessment for performing the surgical procedure. 3D osseus defect was created in the mandibular ramus through a submandibular incision and the osseous shell plates were stabilized with osteosynthesis fixation screws and defect filled with particular bone grafting material. The in-vivo surgical procedures were conducted in four 8-week-old NZW rabbits utilising two osseous shell materials: xenogenic human cortical plates, and autogenous rabbit cortical plates, and the created 3D defects were filled using xenograft and allograft bone grafting materials. The healed defects were evaluated for bone regeneration after 12 weeks using histological and Cone Beam Computed Tomography (CBCT) imaging analysis. Results: Clinical analysis at 12 weeks after surgery revealed the stability of the 3D grafted bone augmentation defects using the osseous shell technique. Imaging and histological analyses confirmed the effectiveness of this model in assessing bone regeneration. Conclusion: The rabbit model is an efficient and reliable biological method for creating a seizable three-dimensional horizontal and vertical bone regeneration model in the mandibular ramus using osseous shell technique for testing various bone-substitute materials testing without compromising the health of the animal. The filled defects could be analyzed for osteogenesis, quantification of bone formation, and healing potential, using histomorphometric analysis, in addition to 3D morphologic evaluation using radiation imaging.

OS047. Quantification of placental vascularization in a rabbit model ofIUGR with three-dimensional power doppler angiography

2012 ◽  
Vol 2 (3) ◽  
pp. 202-203
Author(s):  
E. Lecarpentier ◽  
O. Morel ◽  
A. Tarrade ◽  
E. Gayat ◽  
P. Chavatte Palmer ◽  
...  
Keyword(s):  
Power Doppler ◽  
Rabbit Model ◽  
Three Dimensional

EVALUATION OF THREE DIMENSIONAL CONSTRUCT ENGINEERED FROM POLY(LACTIC-CO-GLYCOLIC ACID)/FIBRIN HYBRID SCAFFOLD USING RABBIT BONE MARROW MESENCHYMAL STEM CELLS FOR OSTEOCHONDRAL DEFECT REPAIR

2015 ◽  
Vol 77 (25) ◽  
Author(s):  
Rozlin Abdul Rahman ◽  
Norhamiza Mohamad Sukri ◽  
Noorhidayah Md Nazir ◽  
Muhammad Aa’zamuddin Ahmad Radzi ◽  
Ahmad Hafiz Zulkifly ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Glycolic Acid ◽  
Osteochondral Defect ◽  
Rabbit Model ◽  
Three Dimensional ◽  
Marker Genes ◽  
Repair Capacity ◽  
Marrow Mesenchymal Stem Cells

Articular cartilage has poor repair capacity due to its avascular and aneural properties and has relatively few cells. This study investigated the ability of autologous implantation approach using three dimensional (3D) constructs engineered from bone marrow mesenchymal stem cells (BMSCs) seeded on poly(lactic-co-glycolic acid) (PLGA) with or without fibrin as cells carrier for the repair of osteochondral defect in rabbit model. The engineered 3D constructs – PLGA/Fibrin/BMSCs and PLGA/BMSCs – were cultured for 3 weeks in vitro and implanted autologously to the osteochondral defect created in the rabbit knee. The in vivo constructs were harvested and evaluated by means of gross observation, histology assessment, gene expression study, sulphated glycosaminoglycan (sGAG) production assay and biomechanical evaluation at 6 and 12 weeks post implantation. The results showed that the osteochondral defects treated with the PLGA/Fibrin/BMSCs constructs exhibited better repairment, more cartilaginous extracellular matrix, higher sGAG production, superior compressive strength and more intense expression of chondrogenic marker genes than the PLGA/BMSCs group. This study suggested that the PLGA/Fibrin/BMSCs has the potential to treat osteochondral defect and may be presented as a viable therapeutic option for those who would be in need from the life-extending benefits of tissue replacement or repair.

scholarly journals Evaluation of Three-Dimensional Chitosan-Agarose-Gelatin Cryogel Scaffold for the Repair of Subchondral Cartilage Defects: AnIn VivoStudy in a Rabbit Model

2014 ◽  
Vol 20 (23-24) ◽  
pp. 3101-3111 ◽  
Author(s):  
Ankur Gupta ◽  
Sumrita Bhat ◽  
Pankaj R. Jagdale ◽  
Bhushan P. Chaudhari ◽  
Lars Lidgren ◽  
...  
Keyword(s):  
Rabbit Model ◽  
Three Dimensional ◽  
Cartilage Defects

Noninvasive three-dimensional cardiac activation imaging on a rabbit model

2009 ◽  
Author(s):  
Chengzong Han ◽  
Chenguang Liu ◽  
S. Pogwizd ◽  
Bin He
Keyword(s):  
Rabbit Model ◽  
Three Dimensional

Quantification of utero-placental vascularization in a rabbit model of IUGR with three-dimensional power Doppler angiography

Placenta ◽  
2012 ◽  
Vol 33 (10) ◽  
pp. 769-775 ◽  
Author(s):  
E. Lecarpentier ◽  
O. Morel ◽  
A. Tarrade ◽  
M. Dahirel ◽  
M. Bonneau ◽  
...  
Keyword(s):  
Power Doppler ◽  
Rabbit Model ◽  
Three Dimensional
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