High-Frequency Ultrasound Investigation of Port-Wine Stains: Hemodynamic Features Revealed By 10- and 22-MHz Transducers

2018 ◽  
Vol 38 (3) ◽  
pp. 641-648 ◽  
Author(s):  
Xia Gong ◽  
Wenxin Yu ◽  
Jia Li ◽  
Angang Ding ◽  
Ping Xiong ◽  
...  
2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Ahmad Taha Khalaf ◽  
Yonghong Sun ◽  
Fang Wang ◽  
Minmin Sheng ◽  
Yan Li ◽  
...  

This study aims at exploring the clinical efficacy and sonographic changes of photodynamic therapy (PDT) using Hematoporphyrin Monomethyl Ether (HMME) for the treatment of port-wine stains (PWS). Forty-five patients with PWS were recruited between March 2017 and June 2018 from the Department of Dermatology of The Third Affiliated Hospital of Soochow University. Five cases were of the pink type, thirty-nine cases were of the purple-red type, and one case was of the thickened type. All patients received three treatment sessions of PDT. After covering normal skin outside the treated area, patients received an intravenous injection of 5 mg/kg HMME within 20 minutes. The affected areas were exposed to a 532 nm LED light and were kept vertically at a distance of 10 cm. The irradiation energy density was set between 80 and 110 J/cm2 in 15-minute sessions. Intermittent power density adjustment was performed at a rate of 5 mW/cm2, and the treatment was withheld when the endpoint reaction appeared. Three follow-ups were performed before and after treatment, respectively, and the efficacy, thickness, and density of skin before and after treatment were evaluated with high-frequency ultrasound. The overall efficacy rate was 97.78% in forty-five cases after treatment for three sessions. Efficacy was related to age (P=0.029) and lesion severity (P<0.001). There were significant differences in the efficacy between the groups of <18 years old, 18-29 years old, and >29 years old (P=0.029). A marked decrease in the numbers of distorted enlarged blood vessels per unit of the lesion was observed under high-frequency ultrasound. There were significant differences in skin thickness and skin density before and after treatment (F=14.528, 5.428, P<0.001). The swelling was reported to varying degrees in the treated areas in 23 patients with cheek lesion and in 6 frontal lesions. Hyperpigmentation after inflammation was observed in four patients that faded spontaneously after two months. In conclusion, photodynamic therapy for the treatment of PWS using HMME is effective and safe with few adverse reactions. Moreover, monitoring the changes in skin thickness and density of lesion tissue using high-frequency ultrasound can objectively evaluate the clinical efficacy of HMME photodynamic therapy and provide the basis for the formulation of individualized photodynamic therapy.


Reumatismo ◽  
2019 ◽  
Vol 71 (3) ◽  
pp. 160-162 ◽  
Author(s):  
B. Ruaro ◽  
M. Cutolo ◽  
E. Alessandri ◽  
F. Zaottini ◽  
R. Picasso ◽  
...  

Patellar tendinopathy, or Jumper’s knee, is a painful knee condition caused by inflammation of the patella tendon. This condition is most frequently observed in subjects who play sports that require repetitive regular jumping. Jumper’s knee is frequently misdiagnosed as a minor injury and many athletes, like our patient, keep on training and competing and either tend to ignore the injury or attempt to treat it themselves. However, jumper’s knee is a serious condition that requires a correct and timely diagnosis, which often necessitates ultrasound investigation in order to start the most appropriate treatment.


2000 ◽  
Vol 11 (5) ◽  
pp. 297-302 ◽  
Author(s):  
M Micallef ◽  
W C Torreggiani ◽  
M Hurley ◽  
W W Dinsmore ◽  
B Hogan

The objectives of this study were to: (1) establish the causes of scrotal swelling in the hospital catchment population; (2) define the role of high frequency ultrasound examination in the management of scrotal swelling. A retrospective study of 582 patients who had high frequency ultrasound examination was carried out. Those requiring more information on perfusion had colour doppler examination. Forty-four per cent of examinations were performed for scrotal swelling. The cause of the scrotal swelling was mainly extratesticular (75% of all scrotal swellings), hydrocele being the commonest. Of the intratesticular causes, infection (50.8%) and tumour (20.6%) were the commonest. In conclusion ultrasound examination distinguishes extratesticular (almost always benign) from intratesticular (potentially malignant) causes of scrotal swelling. Infection, trauma and torsion mimic the ultrasound appearance of tumour as do rare benign entities.


Medicine ◽  
2019 ◽  
Vol 98 (37) ◽  
pp. e17111 ◽  
Author(s):  
Xiang-qin Gao ◽  
Xiao-mei Xue ◽  
Jian-kang Zhang ◽  
Fei Yan ◽  
Qiu-xia Mu

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