scholarly journals An anticopper antiangiogenic approach for advanced cancer in spontaneously occurring tumors using tetrathiomolybdate: A pilot study in a canine animal model

2004 ◽  
Vol 17 (1) ◽  
pp. 9-20 ◽  
Author(s):  
Michael S. Kent ◽  
Bruce R. Madewell ◽  
Gillian Dank ◽  
Robert Dick ◽  
Sofia D. Merajver ◽  
...  
Keyword(s):  
Animal Model ◽  
Pilot Study ◽  
Advanced Cancer

scholarly journals Shifting Palliative Care Paradigm in Primary Care From Better Death to Better End-of-Life : A Swiss Pilot Study

2021 ◽  
Author(s):  
Johanna Sommer ◽  
Christopher Chung ◽  
Dagmar M. Haller ◽  
Sophie Pautex
Keyword(s):  
Quality Of Life ◽  
Primary Care ◽  
Palliative Care ◽  
Pilot Study ◽  
End Of Life ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Communication Skills ◽  
Advanced Cancer Patients

Abstract Background: Patients suffering from advanced cancer often loose contact with their primary care physician (PCP) during oncologic treatment and palliative care is introduced very late.The aim of this pilot study was to test the feasibility and procedures for a randomized trial of an intervention to teach PCPs a palliative care approach and communication skills to improve advanced cancer patients’ quality of life. Methods: Observational pilot study in 5 steps. 1) Recruitment of PCPs. 2) Intervention: training on palliative care competencies and communication skills addressing end-of-life issues.3) Recruitment of advanced cancer patients by PCPs. 4) Patients follow-up by PCPs, and assessment of their quality of life by a research assistant 5) Feedback from PCPs using a semi-structured focus group and three individual interviews with qualitative deductive theme analysis.Results: 8 PCPs were trained. PCPs failed to recruit patients for fear of imposing additional loads on their patients. PCPs changed their approach of advanced cancer patients. They became more conscious of their role and responsibility during oncologic treatments and felt empowered to take a more active role picking up patient’s cues and addressing advance directives. They developed interprofessional collaborations for advance care planning. Overall, they discovered the role to help patients to make decisions for a better end-of-life.Conclusions: PCPs failed to recruit advanced cancer patients, but reported a change in paradigm about palliative care. They moved from a focus on helping patients to die better, to a new role helping patients to define the conditions for a better end-of-life.Trial registration : The ethics committee of the canton of Geneva approved the study (2018-00077 Pilot Study) in accordance with the Declaration of Helsinki

Methylphenidate for fatigue in advanced cancer: A prospective open-label pilot study

2001 ◽  
Vol 18 (3) ◽  
pp. 187-192 ◽  
Author(s):  
Nabeel Sarhill ◽  
Declan Walsh ◽  
Kristine A. Nelson ◽  
Jade Homsi ◽  
Susan LeGrand ◽  
...  
Keyword(s):  
Pilot Study ◽  
Advanced Cancer ◽  
Open Label

The daily dynamics of loss orientation and life engagement in advanced cancer: A pilot study to characterise patterns of adaptation at the end of life

2018 ◽  
Vol 27 (4) ◽  
pp. e12842 ◽  
Author(s):  
S. Vehling ◽  
D. Gerstorf ◽  
F. Schulz-Kindermann ◽  
K. Oechsle ◽  
R. Philipp ◽  
...  
Keyword(s):  
Pilot Study ◽  
End Of Life ◽  
Advanced Cancer ◽  
Life Engagement

Parents With Advanced Cancer: Worries About Their Children’s Unspoken Concerns

2020 ◽  
pp. 104990912096912
Author(s):  
Mary Ellen Shands ◽  
Frances Marcus Lewis
Keyword(s):  
Content Analysis ◽  
Grounded Theory ◽  
Pilot Study ◽  
Advanced Cancer ◽  
Telephone Intervention ◽  
Incurable Cancer ◽  
Emotional Burden ◽  
Cancer Data ◽  
Study Results ◽  
Parent Concerns

Background: Parents with advanced cancer struggle initiating conversations with their children about the cancer. When parents do not have the tools to talk with their children, they silently watch their children attempt to navigate their illness but can only wonder but not know what their children are thinking. The objective of the current study is to describe, from parents living with advanced cancer, the worries and concerns parents wonder their child holds, but has not spoken, about the parent’s cancer. Methods: Twenty-seven parents with incurable cancer enrolled in a 5 session telephone intervention pilot study during which they were asked, “What questions do you have about what your child is thinking or feeling about the cancer?” Data were transcribed and inductively coded using content analysis methods adapted from grounded theory. Results: Analysis yielded 14 categories of parent concerns organized into 6 larger conceptual domains: Being Concerned and Scared about My Cancer; Worrying about Me; Changing How We Talk and Live Day-to-Day; Not Knowing What Will Happen; Having Unanswered Questions about My Cancer; and Understanding My Disease Is Terminal. Conclusions: Study results add to our understanding of the magnitude of the emotional burden parents with advanced cancer carry as they struggle to balance their diagnosis and treatment and their life as parents.

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