Preparative and scaled‐up separation of high‐purity α‐linolenic acid from perilla seed oil by conventional and pH‐zone refining counter current chromatography

2019 ◽  
Vol 42 (14) ◽  
pp. 2360-2370
Author(s):  
Tian Han ◽  
Guang Yang ◽  
Xueli Cao ◽  
Haoze Li ◽  
Hairun Pei ◽  
...  
Keyword(s):  
Linolenic Acid ◽  
High Purity ◽  
Seed Oil ◽  
Zone Refining ◽  
Counter Current ◽  
Perilla Seed

scholarly journals A Pilot Study: Effects of Dietary Supplementation with α-Linolenic Acid-Enriched Perilla Seed Oil on Bronchial Asthma

1997 ◽  
Vol 46 (3) ◽  
pp. 181-185 ◽  
Author(s):  
Kozo Ashida ◽  
Fumihiro Mitsunobu ◽  
Takashi Mifune ◽  
Yasuhiro Hosaki ◽  
Satoshi Yokota ◽  
...  
Keyword(s):  
Pilot Study ◽  
Linolenic Acid ◽  
Bronchial Asthma ◽  
Seed Oil ◽  
Dietary Supplementation ◽  
Perilla Seed

Production of Structured Triacylglycerols from Perilla Seed Oil and Tripalmitin Catalyzed by Lipozyme RM IM

2014 ◽  
Vol 1033-1034 ◽  
pp. 777-780
Author(s):  
Xu Dong Wang ◽  
Xi Liu ◽  
Xing Yu Zhao ◽  
Wei Jie Zhu ◽  
Jun Wang
Keyword(s):  
Fatty Acids ◽  
Linolenic Acid ◽  
Seed Oil ◽  
Acyl Donor ◽  
Omega 3 ◽  
Urea Complexation ◽  
Lipozyme Rm Im ◽  
Alkali Hydrolysis ◽  
Structured Triacylglycerols ◽  
Perilla Seed

Unsaturated free fatty acids (UFFAs), which are rich inα-linolenic and omega-3 fatty acids, were obtained by alkali hydrolysis and urea complexation methods from perilla seed oil and used as the acyl donor to produce structured triacylglycerols (STAGs) catalyzed by Lipozyme RM IM. The results indicated that the content ofα-linolenic acid was increased to 73.16 % after urea complexation methods. The highest incorporation rate ofα-linolenic acid was 58.78 %, which were achieved under the optimum conditions: a molar mass ratio of tripalmitin to UFFAs of 1:12, a reaction time of 48 h and a temperature of 60 °C.

Outcomes of Perilla Seed Oil as an Additional Neuroprotective Therapy in Patients with Mild to Moderate Dementia: A Randomized Control Trial

2019 ◽  
Vol 16 (2) ◽  
pp. 146-155
Author(s):  
Chuntida Kamalashiran ◽  
Kusuma Sriyakul ◽  
Junya Pattaraarchachai ◽  
Sombat Muengtaweepongsa
Keyword(s):  
Cognitive Function ◽  
Randomized Control Trial ◽  
Seed Oil ◽  
Ldl Cholesterol ◽  
Neuroprotective Effects ◽  
Moderate Dementia ◽  
Neuroprotective Therapy ◽  
Randomized Control ◽  
Experimental Group ◽  
Perilla Seed

Background: Dementia is a common medical disorder in the elderly. Oxidative stress plays a major role in the process of cognitive decline in dementia. Perilla seed oil demonstrates its neuroprotective effects via anti-oxidative mechanisms against dementia. We investigate neuroprotective effects of perilla seed oil as an additional treatment in patients with mild to moderate dementia. </P><P> Method: A double-blind, randomized-control trial (perilla seed oil versus placebo) in patients with mild to moderate dementia was conducted. Perilla seed oil or placebo was added on with standard treatment for six months. Cognitive function was compared at nine months after enrollment. </P><P> Result: 182 patients, with 94 in the experimental group and 88 in the placebo group, were able to complete the study. Cognitive function is not significantly different compared between groups. However, the total cholesterol and LDL cholesterol were significantly lower in the experimental group. Perilla seed oil had no adverse effect to kidney, liver, blood components or glucose metabolism. Conclusion: Perilla seed oil as additional neuroprotective therapy in patients with mild to moderate dementia does not improve cognitive function. Perilla seed oil significantly reduced total cholesterol and LDL cholesterol. A clinical trial is needed to prove the benefit of cholesterol-lowering effects with perilla seed oil in human.

scholarly journals Research Status of High-Purity Metals Prepared by Zone Refining

Materials ◽  
2021 ◽  
Vol 14 (8) ◽  
pp. 2064
Author(s):  
Liang Yu ◽  
Xiaoan Kang ◽  
Luona Chen ◽  
Kun Luo ◽  
Yanli Jiang ◽  
...  
Keyword(s):  
Parameter Optimization ◽  
Future Development ◽  
High Purity ◽  
Impurity Content ◽  
Physical Method ◽  
Zone Refining ◽  
Relevant Research ◽  
Research Status ◽  
Analysis Methods ◽  
Theoretical Foundations

The zone refining method is a physical method for effectively purifying metals. Increasing yield and reducing impurity content have always been the focus of its research. This article systematically summarizes the relevant research on the production of high-purity metals by zone refining, including mechanisms, parameter optimization, zone refining types, analysis methods, limitations, and future development directions, and it provides relevant theoretical foundations for the production of high-purity metals as well.

scholarly journals Perilla Seed Oil Enhances Cognitive Function and Mental Health in Healthy Elderly Japanese Individuals by Enhancing the Biological Antioxidant Potential

Foods ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1130
Author(s):  
Michio Hashimoto ◽  
Kentaro Matsuzaki ◽  
Shahdat Hossain ◽  
Tomoko Ito ◽  
Harumi Wakatsuki ◽  
...  
Keyword(s):  
Mental Health ◽  
Cognitive Function ◽  
Plasma Membranes ◽  
Seed Oil ◽  
Antioxidant Potential ◽  
Control Group ◽  
Healthy Elderly ◽  
Age Related ◽  
Elderly Japanese ◽  
Perilla Seed

Oxidative stress plays an important role in age-associated cognitive decline. We recently reported that dietary intake of perilla seed oil (PO), a rich source of α-linolenic acid (LNA, C18:3, ω-3), helps in maintaining good mental health in adults. This study aimed to investigate the impacts of dietary PO intake on cognitive functions and mental health in healthy, elderly Japanese individuals. Seventy-five healthy volunteers aged 64–84 years were randomly divided into two groups: a control group and a PO-administered group. At baseline and at 12 months of intervention, cognitive function, mental health condition, fatty acid profile of the red blood cell plasma membranes (RBC-PM), and serum biochemical parameters were evaluated. Results showed that serum biological antioxidant potential and LNA levels in the RBC-PM at 12 months after the trial were significantly higher in the PO group compared to the control group. Further, both the cognitive function measures, as evaluated by the Frontal Assessment Battery test and the apathy scores, tended to be improved after 12 months in the PO group. Our results demonstrate that dietary PO intake enhances the antioxidant potential and prevents the age-related cognitive and mental decline in healthy elderly individuals by enhancing the blood LNA levels.

Large-scale separation of alkaloids from Corydalis decumbens by pH-zone-refining counter-current chromatography

2006 ◽  
Vol 1115 (1-2) ◽  
pp. 267-270 ◽  
Author(s):  
Xiao Wang ◽  
Yanling Geng ◽  
Fuwei Li ◽  
Xingang Shi ◽  
Jianhua Liu
Keyword(s):  
Large Scale ◽  
Zone Refining ◽  
Scale Separation ◽  
Counter Current
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