Simultaneous determination of selected estrogenic endocrine disrupting chemicals and bisphenol A residues in whole milk using fabric phase sorptive extraction coupled to HPLC-UV detection and LC-MS/MS

2018 ◽  
Vol 42 (2) ◽  
pp. 598-608 ◽  
Author(s):  
Rodolfo Mesa ◽  
Abuzar Kabir ◽  
Victoria Samanidou ◽  
Kenneth G. Furton
Keyword(s):  
Bisphenol A ◽  
Simultaneous Determination ◽  
Endocrine Disrupting Chemicals ◽  
Uv Detection ◽  
Sorptive Extraction ◽  
Whole Milk ◽  
Endocrine Disrupting ◽  
Estrogenic Endocrine Disrupting Chemicals

The Combination of 17-Estradiol and Bisphenol A Weaken their Respective Action

2010 ◽  
Vol 113-116 ◽  
pp. 2220-2223
Author(s):  
Lang Lang ◽  
Gaung Ming Zhang ◽  
Yu Li
Keyword(s):  
Cell Cycle ◽  
Bisphenol A ◽  
Cancer Cell ◽  
Endocrine Disrupting Chemicals ◽  
Estrogen Receptor Α ◽  
S Phase ◽  
Cancer Cell Growth ◽  
Endocrine Disrupting ◽  
Mcf 7

17-Estradiol (E2) and Bisphenol A (BPA) are important endocrine disrupting chemicals (EDCs). In this work, cell proliferation assay using cell cycle analysis method and determination of estrogen receptor α protein was used to investigated the mechanism and effects respectively and in mixture of the two EDCs in stimulating the growth of human breast cancer MCF-7 cell When the concentration of E2 and BPA were 10-12mol/L and 10-8mol/L respectively, E2 and BPA could reduce the express of ERα protein by activated ERα pathway, accelerated the cell cycle, decreased the percentages of cells in G0/1 phase, increased the percentages of cells in S phase at 48 h, and thus promoted the cancer cell growth. However, the combination effect of these two compounds did not induce the growth of cancer cell and the mixture reduced the ratio in S phase compared with E2 or BPA alone, which lead to weakening of the proliferation ability. There was a significant interaction between BPA and E2 and such a weakening effect had not been reported before.

Effect of Polyphosphate on Removal of Endocrine-Disrupting Chemicals of Nonylphenol and Bisphenol-A by Activated Carbons

2005 ◽  
Vol 40 (4) ◽  
pp. 484-490 ◽  
Author(s):  
Keun J. Choi ◽  
Sang G. Kim ◽  
Chang W. Kim ◽  
Seung H. Kim
Keyword(s):  
Activated Carbon ◽  
Bisphenol A ◽  
Surface Charge ◽  
Activated Carbons ◽  
Endocrine Disrupting Chemicals ◽  
Dipole Interaction ◽  
High Affinity ◽  
Calcium Polyphosphate ◽  
Endocrine Disrupting ◽  
Positively Charged

Abstract This study examined the effect of polyphosphate on removal of endocrine-disrupting chemicals (EDCs) such as nonylphenol and bisphenol-A by activated carbons. It was found that polyphosphate aided in the removal of nonylphenol and bisphenol- A. Polyphosphate reacted with nonylphenol, likely through dipole-dipole interaction, which then improved the nonylphenol removal. Calcium interfered with this reaction by causing competition. It was found that polyphosphate could accumulate on carbon while treating a river. The accumulated polyphosphate then aided nonylphenol removal. The extent of accumulation was dependent on the type of carbon. The accumulation occurred more extensively with the wood-based used carbon than with the coal-based used carbon due to the surface charge of the carbon. The negatively charged wood-based carbon attracted the positively charged calcium-polyphosphate complex more strongly than the uncharged coal-based carbon. The polyphosphate-coated activated carbon was also effective in nonylphenol removal. The effect was different depending on the type of carbon. Polyphosphate readily attached onto the wood-based carbon due to its high affinity for polyphosphate. The attached polyphosphate then improved the nonylphenol removal. However, the coating failed to attach polyphosphate onto the coal-based carbon. The nonylphenol removal performance of the coal-based carbon remained unchanged after the polyphosphate coating.

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