Electrospun polyethylene terephthalate/graphene oxide nanofibrous membrane followed by HPLC for the separation and determination of tamoxifen in human blood plasma

2017 ◽  
Vol 40 (17) ◽  
pp. 3383-3391 ◽  
Author(s):  
Hassan Sereshti ◽  
Sadjad Bakhtiari ◽  
Hamid Najarzadekan ◽  
Soheila Samadi
Keyword(s):  
Graphene Oxide ◽  
Blood Plasma ◽  
Polyethylene Terephthalate ◽  
Human Blood ◽  
Nanofibrous Membrane ◽  
Human Blood Plasma

Molecular Imprinted Graphene Oxide Nanocomposite for Optical Sensing of Nicotine in Human Blood Plasma

2020 ◽  
Vol 42 (6) ◽  
pp. 856-856
Author(s):  
Sehrish Qazi Sehrish Qazi ◽  
Huma Shaikh Huma Shaikh ◽  
Ayaz Ali Memon Ayaz Ali Memon ◽  
and Shahabuddin Memon and Shahabuddin Memon
Keyword(s):  
Graphene Oxide ◽  
Human Plasma ◽  
Human Blood ◽  
Optical Sensor ◽  
Single Layer ◽  
Human Blood Plasma ◽  
Buffer Concentration ◽  
Imprinted Polymer ◽  
Ft Ir

Among all psychotropic alkaloids, nicotine is more addictive, carcinogenic and capable of causing many health problems. This work is based on the development of highly robust, cheap, reliable, selective and sensitive nicotine imprinted graphene oxide nanocomposite (ImpGO nanocomposite) based optical sensor for determination of nicotine in human plasma. The ImpGO nanocomposite has been thoroughly characterized using different techniques i.e. FT-IR, SEM, TEM, Raman, etc. These characterizations revealed that ImpGO nanocomposite is comprised of single layer of graphene oxide successfully modified with imprinted polymer. The synthesized material was utilized to selectively determine nicotine using UV-vis spectrophotometer in BR buffer of 0.1 M at pH 3 and diluted human plasma. The effect of parameters such as buffer concentration, pH, amount of nanocomposite, etc on determination of nicotine using ImpGO nanocomposite were studied thoroughly. Thus, a sensitive optical method was developed for determination of nicotine in human plasma with linear range of 22-370 pM along with LOD and LOQ of 7 pM and 22 pM, respectively. The selectivity of sensor was evaluated using homologues of nicotine such as nicotine amide, caffeine and cotinine. The results obtained from biological samples showed that developed optical sensor is efficient in complex matrices of real sample.

scholarly journals The determination of nitrite and nitrate in human blood plasma by capillary electrophoresis.

1996 ◽  
Vol 40 (4) ◽  
pp. 175-181 ◽  
Author(s):  
Toshiko Ueda ◽  
Tsuyoshi Maekawa ◽  
Daikai Sadamitsu ◽  
Ryosuke Tsuruta ◽  
Kazuyuki Nakamura
Keyword(s):  
Capillary Electrophoresis ◽  
Blood Plasma ◽  
Human Blood ◽  
Human Blood Plasma

scholarly journals Development and validation of method for quantitative determination of sildenafil and n-desmethyl sildenafil by HPLC-MS/MS in human blood plasma

2017 ◽  
Vol 0 (1 (5)) ◽  
pp. 22-32 ◽  
Author(s):  
Igor Kuznetsov ◽  
Helen Naumenko ◽  
Nataliia Reznichenko ◽  
Andrey Kostiuk ◽  
Roman Savyak ◽  
...  
Keyword(s):  
Quantitative Determination ◽  
Blood Plasma ◽  
Human Blood ◽  
Human Blood Plasma ◽  
Development And Validation

Capillary electrophoresis coupled with chloroform-acetonitrile extraction for rapid and highly selective determination of cysteine and homocysteine levels in human blood plasma and urine

2017 ◽  
Vol 38 (20) ◽  
pp. 2646-2653 ◽  
Author(s):  
Alexander Vladimirovich Ivanov ◽  
Polina Olegovna Bulgakova ◽  
Edward Danielevich Virus ◽  
Maria Petrovna Kruglova ◽  
Valery Vasil'evich Alexandrin ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Blood Plasma ◽  
Human Blood ◽  
Human Blood Plasma ◽  
Selective Determination
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