Development of an automated dual‐mode supercritical fluid chromatography and reversed‐phase liquid chromatography mass‐directed purification system for small‐molecule drug discovery

Kanaka Hettiarachchi; May Kong; Andersen Yun; John R. Jacobsen; Qifeng Xue

doi:10.1002/jssc.201301366

Development of an automated dual‐mode supercritical fluid chromatography and reversed‐phase liquid chromatography mass‐directed purification system for small‐molecule drug discovery

Journal of Separation Science ◽

10.1002/jssc.201301366 ◽

2014 ◽

Vol 37 (7) ◽

pp. 775-781 ◽

Cited By ~ 6

Author(s):

Kanaka Hettiarachchi ◽

May Kong ◽

Andersen Yun ◽

John R. Jacobsen ◽

Qifeng Xue

Keyword(s):

Liquid Chromatography ◽

Drug Discovery ◽

Supercritical Fluid ◽

Supercritical Fluid Chromatography ◽

Reversed Phase ◽

Reversed Phase Liquid Chromatography ◽

Dual Mode ◽

Small Molecule Drug ◽

Purification System ◽

Phase Liquid

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Purification of lignans from Fructus Arctii using off-line two-dimensional supercritical fluid chromatography/reversed-phase liquid chromatography

Journal of Separation Science ◽

10.1002/jssc.201700139 ◽

2017 ◽

Vol 40 (16) ◽

pp. 3231-3238 ◽

Cited By ~ 8

Author(s):

Bichao Yang ◽

Huaxia Xin ◽

Feier Wang ◽

Jianfeng Cai ◽

Yanfang Liu ◽

...

Keyword(s):

Liquid Chromatography ◽

Supercritical Fluid ◽

Supercritical Fluid Chromatography ◽

Reversed Phase ◽

Two Dimensional ◽

Reversed Phase Liquid Chromatography ◽

Phase Liquid

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Separation of Piper kadsura Using Preparative Supercritical Fluid Chromatography Combined with Preparative Reversed-Phase Liquid Chromatography

Chromatographia ◽

10.1007/s10337-018-3544-y ◽

2018 ◽

Vol 81 (8) ◽

pp. 1181-1187 ◽

Cited By ~ 4

Author(s):

Huaxia Xin ◽

Zhuoshun Dai ◽

Jianfeng Cai ◽

Yanxiong Ke ◽

Jiatao Feng ◽

...

Keyword(s):

Liquid Chromatography ◽

Supercritical Fluid ◽

Supercritical Fluid Chromatography ◽

Reversed Phase ◽

Reversed Phase Liquid Chromatography ◽

Phase Liquid

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Simultaneous achiral-chiral analysis of pharmaceutical compounds using two-dimensional reversed phase liquid chromatography-supercritical fluid chromatography

Talanta ◽

10.1016/j.talanta.2015.10.054 ◽

2016 ◽

Vol 148 ◽

pp. 548-555 ◽

Cited By ~ 41

Author(s):

C.J. Venkatramani ◽

Mohammad Al-Sayah ◽

Guannan Li ◽

Meenakshi Goel ◽

James Girotti ◽

...

Keyword(s):

Liquid Chromatography ◽

Supercritical Fluid ◽

Supercritical Fluid Chromatography ◽

Pharmaceutical Compounds ◽

Reversed Phase ◽

Chiral Analysis ◽

Two Dimensional ◽

Reversed Phase Liquid Chromatography ◽

Phase Liquid

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Application of off-line two dimensional reversed-phase liquid chromatography/supercritical fluid chromatography to the separation of the seeds of Trichosanthes kirilowii Maxim

Chinese Journal of Chromatography ◽

10.3724/sp.j.1123.2017.03003 ◽

2017 ◽

Vol 35 (7) ◽

pp. 683

Author(s):

Yun YUAN ◽

Huaxia XIN ◽

Ziyue PENG ◽

Qing FU ◽

Yu JIN

Keyword(s):

Liquid Chromatography ◽

Supercritical Fluid ◽

Supercritical Fluid Chromatography ◽

Reversed Phase ◽

Two Dimensional ◽

Reversed Phase Liquid Chromatography ◽

Trichosanthes Kirilowii ◽

Phase Liquid

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On-line coupling of achiral Reversed Phase Liquid Chromatography and chiral Supercritical Fluid Chromatography for the analysis of pharmaceutical compounds

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2018.06.058 ◽

2018 ◽

Vol 159 ◽

pp. 237-244 ◽

Cited By ~ 14

Author(s):

Marion Iguiniz ◽

Estelle Corbel ◽

Nicolas Roques ◽

Sabine Heinisch

Keyword(s):

Liquid Chromatography ◽

Supercritical Fluid ◽

Supercritical Fluid Chromatography ◽

Pharmaceutical Compounds ◽

Reversed Phase ◽

Reversed Phase Liquid Chromatography ◽

On Line ◽

Phase Liquid ◽

Line Coupling

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The differences in matrix effect between supercritical fluid chromatography and reversed phase liquid chromatography coupled to ESI/MS

Analytica Chimica Acta ◽

10.1016/j.aca.2017.10.014 ◽

2018 ◽

Vol 1000 ◽

pp. 163-171 ◽

Cited By ~ 21

Author(s):

Alfred Svan ◽

Mikael Hedeland ◽

Torbjörn Arvidsson ◽

Curt E. Pettersson

Keyword(s):

Liquid Chromatography ◽

Supercritical Fluid ◽

Supercritical Fluid Chromatography ◽

Matrix Effect ◽

Reversed Phase ◽

Reversed Phase Liquid Chromatography ◽

Esi Ms ◽

Phase Liquid

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Considerations on comprehensive and off‐line supercritical fluid chromatography×reversed‐phase liquid chromatography for the analysis of triacylglycerols in fish oil

Journal of Separation Science ◽

10.1002/jssc.201000044 ◽

2010 ◽

Vol 33 (10) ◽

pp. 1504-1512 ◽

Cited By ~ 38

Author(s):

Isabelle François ◽

Alberto dos Santos Pereira ◽

Pat Sandra

Keyword(s):

Liquid Chromatography ◽

Fish Oil ◽

Supercritical Fluid ◽

Supercritical Fluid Chromatography ◽

Reversed Phase ◽

Reversed Phase Liquid Chromatography ◽

Phase Liquid

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Construction of an off-line two dimensional reversed-phase liquid chromatography/ultra-high performance supercritical fluid chromatography method for rapid and comprehensive analysis of Piper kadsura

The Journal of Supercritical Fluids ◽

10.1016/j.supflu.2017.03.004 ◽

2017 ◽

Vol 127 ◽

pp. 9-14 ◽

Cited By ~ 7

Author(s):

Huaxia Xin ◽

Qing Fu ◽

Yun Yuan ◽

Yanfang Liu ◽

Yanxiong Ke ◽

...

Keyword(s):

Liquid Chromatography ◽

Supercritical Fluid ◽

Supercritical Fluid Chromatography ◽

High Performance ◽

Reversed Phase ◽

Comprehensive Analysis ◽

Two Dimensional ◽

Reversed Phase Liquid Chromatography ◽

Chromatography Method ◽

Phase Liquid

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Comprehensive supercritical fluid chromatography×reversed phase liquid chromatography for the analysis of the fatty acids in fish oil

Journal of Chromatography A ◽

10.1016/j.chroma.2009.02.078 ◽

2009 ◽

Vol 1216 (18) ◽

pp. 4005-4012 ◽

Cited By ~ 58

Author(s):

Isabelle François ◽

Pat Sandra

Keyword(s):

Fatty Acids ◽

Liquid Chromatography ◽

Fish Oil ◽

Supercritical Fluid ◽

Supercritical Fluid Chromatography ◽

Reversed Phase ◽

Reversed Phase Liquid Chromatography ◽

Phase Liquid

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Construction of a new interface for comprehensive supercritical fluid chromatography×reversed phase liquid chromatography (SFC×RPLC)

Journal of Separation Science ◽

10.1002/jssc.200800267 ◽

2008 ◽

Vol 31 (19) ◽

pp. 3473-3478 ◽

Cited By ~ 32

Author(s):

Isabelle François ◽

Alberto dos Santos Pereira ◽

Frédéric Lynen ◽

Pat Sandra

Keyword(s):

Liquid Chromatography ◽

Supercritical Fluid ◽

Supercritical Fluid Chromatography ◽

Reversed Phase ◽

Reversed Phase Liquid Chromatography ◽

Phase Liquid

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