Simultaneous determination of dihydroxybenzene positional isomers by capillary electrochromatography using gold nanoparticles as stationary phase

2012 ◽  
Vol 35 (8) ◽  
pp. 1003-1009 ◽  
Author(s):  
Jian-Feng He ◽  
Fu-Jun Yao ◽  
Hong Cui ◽  
Xiang-Jun Li ◽  
Zhuo-Bin Yuan
Keyword(s):  
Gold Nanoparticles ◽  
Stationary Phase ◽  
Simultaneous Determination ◽  
Capillary Electrochromatography ◽  
Positional Isomers

Simultaneous determination of nucleoside and purine compounds in human urine based on a hydrophobic monolithic column using capillary electrochromatography

2015 ◽  
Vol 36 (21-22) ◽  
pp. 2727-2735 ◽  
Author(s):  
Zongbao Chen ◽  
Chuanghui Huang ◽  
Wei Liu ◽  
Lin Zhang ◽  
Ping Tong ◽  
...  
Keyword(s):  
Simultaneous Determination ◽  
Human Urine ◽  
Capillary Electrochromatography ◽  
Monolithic Column

scholarly journals Simultaneous determination of clobutinol hydrochloride and doxylamine succinate from syrups by RP HPLC using a new stationary phase containing embedded urea polar groups

2012 ◽  
Vol 48 (2) ◽  
pp. 315-323 ◽  
Author(s):  
Paulo Cesar Pires Rosa ◽  
Isabel Cristina Sales Fontes Jardim
Keyword(s):  
Stationary Phase ◽  
Simultaneous Determination ◽  
Reversed Phase ◽  
Hplc Method ◽  
Array Detector ◽  
Polar Groups ◽  
Ich Guidelines ◽  
Relative Standard ◽  
New Stationary Phase

A new, simple, fast, reproducible and sensitive reversed phase HPLC method, using a new stationary phase containing embedded urea polar groups, has been developed and validated for the simultaneous determination of clobutinol hydrochloride (CLO) and doxylamine succinate (DOX) in syrups. The determination was carried out on a C8 urea column (125 mm x 3.9 mm i.d., 5 µm particle size) synthetized at the Liquid Chomatography Laboratory (LabCrom) of the Chemistry Institute of Unicamp. The mobile phase consisted of a mixture of acetonitrile:methanol:phosphate buffer (pH 2.5) in the gradient mode. The diode array detector (DAD) was operated at 230 nm for CLO and 262 nm for DOX. The method showed adequate precision, with relative standard deviations (RSD) less than 1%. The presence of the excipients did not interfere in the results of the analysis. Accuracy was determined by adding standards of the drugs to a placebo and good recovery values were obtained. The analytical curves were linear (r² 0.9999 for CLO and 0.9998 for DOX) over a wide concentration range (2.4-336 µg mL-1 for CLO and 2.3-63 µg mL-1 for DOX). The solutions were stable for at least 72 hours at room temperature. The criteria for validation using the ICH guidelines were fulfilled.

Layer-by-layer self-assembly of polydopamine/gold nanoparticle/thiol coating as the stationary phase for open tubular capillary electrochromatography

2015 ◽  
Vol 7 (19) ◽  
pp. 8227-8234 ◽  
Author(s):  
Xiu-Ju Li ◽  
Qi-Feng Fu ◽  
Qi-Hui Zhang ◽  
Xue-Mei Jiang ◽  
Feng-Qing Yang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Stationary Phase ◽  
Gold Nanoparticle ◽  
Self Assembly ◽  
Capillary Electrochromatography ◽  
Phase Ratio ◽  
Layer By Layer ◽  
Novel Method ◽  
First Time ◽  
High Phase

A novel method for the preparation of permanent coating columns with a high phase ratio based on the multiple properties of PDA and LBL self-assembly of polydopamine/gold nanoparticles/thiols has been developed for the first time.

The Influence of Gold Nanoparticles on Simultaneous Determination of Uric Acid and Ascorbic Acid

2009 ◽  
Vol 43 (1) ◽  
pp. 22-33 ◽  
Author(s):  
Yanping Cui ◽  
Changzhu Yang ◽  
Wenhong Pu ◽  
Munetaka Oyama ◽  
Jingdong Zhang
Keyword(s):  
Gold Nanoparticles ◽  
Ascorbic Acid ◽  
Uric Acid ◽  
Simultaneous Determination
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