Development of a molecularly imprinted polymer for selective extraction of bisphenol A in water samples

2010 ◽  
Vol 33 (11) ◽  
pp. 1644-1651 ◽  
Author(s):  
Francesca Canale ◽  
Chiara Cordero ◽  
Claudio Baggiani ◽  
Patrizia Baravalle ◽  
Cristina Giovannoli ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Molecularly Imprinted Polymer ◽  
Water Samples ◽  
Selective Extraction ◽  
Imprinted Polymer ◽  
Molecularly Imprinted

scholarly journals A graphene oxide surface–molecularly imprinted polymer as a dispersive solid-phase extraction adsorbent for the determination of cefadroxil in water samples

RSC Advances ◽  
2017 ◽  
Vol 7 (54) ◽  
pp. 34077-34085 ◽  
Author(s):  
Xinwei Chen ◽  
Nengsheng Ye
Keyword(s):  
Graphene Oxide ◽  
Molecularly Imprinted Polymer ◽  
Water Samples ◽  
Solid Phase ◽  
Environmental Water ◽  
Selective Extraction ◽  
Oxide Surface ◽  
Imprinted Polymer ◽  
Molecularly Imprinted

Graphene oxide–functionalized molecularly imprinted polymer particles have been prepared for specific selective extraction and determination of cefadroxil in environmental water samples.

scholarly journals A Phenolphthalein-Dummy Template Molecularly Imprinted Polymer for Highly Selective Extraction and Clean-Up of Bisphenol A in Complex Biological, Environmental and Food Samples

Polymers ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1150 ◽  
Author(s):  
Jiajia Yang ◽  
Yun Li ◽  
Chaonan Huang ◽  
Yanna Jiao ◽  
Jiping Chen
Keyword(s):  
Bisphenol A ◽  
Molecularly Imprinted Polymer ◽  
Particle Diameter ◽  
Selective Extraction ◽  
Food Samples ◽  
Array Detector ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Dummy Template ◽  
Relative Standard

A molecularly imprinted polymer (MIP) for highly selective solid-phase extraction (SPE) of bisphenol A (BPA) was prepared using phenolphthalein (PP) as the novel dummy template by bulk polymerization. A particle diameter distribution of 40–60 μm, a specific surface area of 359.8 m2·g−1, and a total pore volume of 0.730 cm3·g−1 for the prepared PP-imprinted polymer (PPMIP) were obtained. Good selectivity and specific adsorption capacity for BPA of the prepared PPMIP were also demonstrated by the chromatographic evaluation and sorption experiments. The PPMIP as a SPE sorbent was evaluated for the selective extraction and clean-up of BPA from complex biological, environmental, and food samples. Meanwhile, an accurate and sensitive analytical method based on the PPMIP-SPE purification procedure coupled with high performance liquid chromatography-diode array detector (HPLC-DAD) detection has been successfully developed for the rapid determination of BPA from these samples, with detection limits of 1.3 ng·mL−1 for bovine serum and milk, 2.6 ng·mL−1 for human urine and edible oil, 5.2 ng·mL−1 for soybean sauce, and 1.3 ng·g−1 for sediment. The BPA recoveries at two different spiking levels were in the range of 82.1–106.9%, with relative standard deviation (RSD) values below 7.7%.

scholarly journals A Molecularly Imprinted Polymer for Selective Extraction of Phenolic Acids from Human Urine

2021 ◽  
Vol 11 (4) ◽  
pp. 1577
Author(s):  
Marco Mora-Granados ◽  
David González-Gómez ◽  
Jin Su Jeong ◽  
Alejandrina Gallego-Picó
Keyword(s):  
Phenolic Acids ◽  
Molecularly Imprinted Polymer ◽  
Human Urine ◽  
Limit Of Detection ◽  
Ph Dependence ◽  
Selective Extraction ◽  
Screening Methods ◽  
Specific Method ◽  
Imprinted Polymer ◽  
Molecularly Imprinted

Studies for monitoring the bioavailability of dietary flavonoid compounds generate great interest. Among them, low-molecular-weight phenolic acids, secondary metabolites present in colonic catabolism and urinary excretion, have been proposed as biomarkers of polyphenol intake. Using 4-hydroxyphenylacetic acid as a template, a molecularly imprinted polymer (MIP) was synthesized for selective extraction of these hydroxylated metabolites from human urine samples and posterior analysis in an HPLC-DAD-MS system. Polymers were characterized by Scanning electron microscopy (SEM), Attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR), Brunauer-Emmett-Teller (BET) method, and binding experiments. MIP presents specific recognition ability for template and analogues molecules. This capacity of recognition and the pH dependence of the binding strength was also studied. The method was validated over a concentration range of 0.25–40 mg/L, r2 > 0.995. In the optimized conditions, the recovery value was 94% with RSD 1.2%. The Limit of Detection (LOD) and Limit of Quantification (LOQ) were 1.22 and 3.69 mg/L, respectively. In our knowledge, it is the first time that this methodology is applied to analyze urinary catabolites of the polyphenol compound and to provide a specific method and simple analysis alternative. The selective extraction of these metabolites improves the application and results obtained by other less sensitive analysis methods than the validation method. It also facilitates the development of new screening methods.

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