Synergistic antitumor activity of combination chemotherapy with mitomycin C and cisplatin against human gastric cancer xenografts in nude mice

1994 ◽  
Vol 56 (4) ◽  
pp. 242-245 ◽  
Author(s):  
Yoshiro Saikawa ◽  
Tetsuro Kubota ◽  
Tsong-Hong Kuo ◽  
Toshiharu Furukawa ◽  
Suguru Kase ◽  
...  
1993 ◽  
Vol 54 (2) ◽  
pp. 98-102 ◽  
Author(s):  
Yoshiro Saikawa ◽  
Tetsuro Kubota ◽  
Tsong-Hong Kuo ◽  
Suguru Kase ◽  
Toshiharu Furukawa ◽  
...  

Author(s):  
Akira Tokunaga ◽  
Masahiko Onda ◽  
Takeshi Okuda ◽  
Tadashi Teramoto ◽  
Tsuyoshi Oguri ◽  
...  

2009 ◽  
Vol 15 (40) ◽  
pp. 5044 ◽  
Author(s):  
Chun-Gen Xing ◽  
Bao-Song Zhu ◽  
Xiao-Qing Fan ◽  
Hui-Hui Liu ◽  
Xun Hou ◽  
...  

1988 ◽  
Vol 58 (1) ◽  
pp. 42-45 ◽  
Author(s):  
S Fujimoto ◽  
M Ohta ◽  
RD Shrestha ◽  
M Kokubun ◽  
T Miyoshi ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-11
Author(s):  
Chen Yu ◽  
Ai-Jun Ji ◽  
Jian-Wei Lu ◽  
Shi-Jia Liu ◽  
Yu Sun

San Leng powder extract has been used as medicinal compound for the prevention and treatment of cancers. The antitumor activity of SLPE was determined by treating BALB/C mice harboring a human gastric cancer xenograft with SPLE for 17 days. Mice were also treated with fluorouracil (5-Fu, 25 mg/kg) or a combination of SLPE and 5-Fu. Our results indicate that the inhibition of tumor growth by SLPE might be due to a block in the cell cycle and the induction of apoptosis. These results suggest that SLPE might be useful in the treatment of gastric cancer.


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