Erythrocyte survival studies in a rat myelogenous leukemia

1982 ◽  
Vol 21 (3) ◽  
pp. 199-203
Author(s):  
Michael J. Derelanko ◽  
Richard C. Meagher ◽  
Joseph Lobue ◽  
Janine A. Khouri ◽  
Albert S. Gordon
Keyword(s):  
Myelogenous Leukemia ◽  
Erythrocyte Survival ◽  
Survival Studies

New possibilities in erythrocyte survival studies with the application of a Well-type germanium semiconductor detector

1991 ◽  
Vol 12 (5) ◽  
pp. 451-460 ◽  
Author(s):  
R. A. DE VRIES ◽  
S. J. OLDENBURG ◽  
T. THELOSEN ◽  
M. DE BRUIN ◽  
J. POORTMAN ◽  
...  
Keyword(s):  
Semiconductor Detector ◽  
Erythrocyte Survival ◽  
Survival Studies

scholarly journals The Use of 125I as a Membrane Protein Label for Erythrocyte Survival Studies

Blood ◽  
1974 ◽  
Vol 43 (4) ◽  
pp. 549-556 ◽  
Author(s):  
Martin Weintraub ◽  
Kenneth Gerson ◽  
Robert Silber
Keyword(s):  
Hydrogen Peroxide ◽  
Membrane Proteins ◽  
Membrane Protein ◽  
Erythrocyte Membrane ◽  
Red Cell ◽  
Cell Component ◽  
Erythrocyte Survival ◽  
Protein Label ◽  
Survival Studies ◽  
Erythrocyte Membrane Proteins

Abstract Radioactive iodide, incubated with erythrocytes in the presence of lactoperoxidase and hydrogen peroxide, is covalently bound to membrane proteins. Using this technique, rabbit erythrocytes were labeled with 125I, reinjected into the donors, and erythrocyte survivals determined. The values for the erythrocyte half-lives and the shape of the decay curves were comparable to those reported using DF32P. Following hemolysis of erythrocytes double labeled with 125I and 51Cr, radioactivity from both these isotopes appeared mainly in liver, lung, kidney, spleen, and urine. Enzymatic iodination provides a noneluting label of erythrocyte membrane proteins for the study of survival, sequestration and turnover of this red cell component.

DETERMINATION OF ERYTHROCYTE SURVIVAL IN NEWBORN INFANTS BY MEANS OF CR51-LABELLED ERYTHROCYTES

PEDIATRICS ◽  
1961 ◽  
Vol 27 (3) ◽  
pp. 354-361 ◽  
Author(s):  
Eugene Kaplan ◽  
Ku Shin Hsu
Keyword(s):  
Life Span ◽  
Precise Measurement ◽  
Newborn Infants ◽  
Full Term ◽  
Term Infants ◽  
Erythrocyte Survival ◽  
Apparent Reduction ◽  
Placental Blood ◽  
Survival Studies

There is no difference in the rate of Cr51 elution from intact cord or adult erythrocytes Variable results of survival studies suggest that placental blood is unsuited for valid and precise measurement of erythrocyte life span. Decreased survival is not present for the erythrocytes of the normal full-term newborn infant in the first 5 days of life when compared with the adult. In the premature infant of the same age shortened life span is found of erythrocytes produced in utero. This may contribute in some degree to the characteristic increase in severity of premature anemia and hyperbilirbinemia. The apparent reduction in erythrocyte life span during the second and third months of life in both premature and full-term infants ma reflect an older erythrocyte population resultant from decreased erythropoiesis in the first weeks of life.

Erythrocyte Survival Studies in Experimental Molybdenosis of Sheep.

1961 ◽  
Vol 107 (4) ◽  
pp. 924-926 ◽  
Author(s):  
J. J. Kaneko ◽  
C. E. Cornelius ◽  
N. F. Baker
Keyword(s):  
Erythrocyte Survival ◽  
Survival Studies

Pathophysiology of ovine trypanosomiasis: ferrokinetics and erythrocyte survival studies

1992 ◽  
Vol 53 (1) ◽  
pp. 80-86 ◽  
Author(s):  
E. Katunguka-Rwakishaya ◽  
M. Murray ◽  
P.H. Holmes
Keyword(s):  
Erythrocyte Survival ◽  
Survival Studies

IN VIVO  ERYTHROCYTE SURVIVAL STUDIES AFTER IN-LINE MICROWAVE WARMING

1991 ◽  
Vol 75 (3) ◽  
pp. A1115-A1115
Author(s):  
R. J. Connolly ◽  
M. J. Allen ◽  
K. Ramberg ◽  
R. Grabowy ◽  
K. Carr ◽  
...  
Keyword(s):  
Erythrocyte Survival ◽  
Survival Studies

scholarly journals Survival Studies of Thalassemic Erythrocytes Transfused into Donors, into Subjects with Thalassemia Minor and into Normal and Splenectomized Subjects

Blood ◽  
1958 ◽  
Vol 13 (8) ◽  
pp. 803-810 ◽  
Author(s):  
C. VULLO ◽  
A. M. TUNIOLI
Keyword(s):  
Normal Subjects ◽  
Thalassemia Major ◽  
Red Cells ◽  
Survival Curves ◽  
Normal Spleen ◽  
Thalassemia Minor ◽  
Wide Range ◽  
Erythrocyte Survival ◽  
Red Cell Survival ◽  
Survival Studies

Abstract The analysis of the curves of thalassemic red cell survival studied in children suffering from thalassemia major, in subjects with thalassemia minor, in normal splenectomized subjects and in healthy persons shows: (a) thalassemic erythrocytes show a marked shortening of life span, with a wide range of half life from case to case; (b) thalassemic erythrocytes survive longer in patients with thalassemia major and minor than in normal subjects; (c) the behavior of thalassemic erythrocyte survival curves in the anemic patients and in the normal splenectomized cases is almost similar. On the basis of these results, the authors emphasize that: (1) valuable data on the seriousness of the hemolytic process in thalassemia major can be drawn only from autotransfusion studies; (2) in both thalassemia major and minor the spleen has less hemolytic activity on thalassemic red cells than in normal subjects; (3) since survival curves between anemic and normal subjects differ principally in the initial component where the most abnormal red cells are destroyed by the normal spleen, it is probable that the spleen of Patients with thalassemia major is not so greatly active against these cells.

The Life Span and Osmotic Fragility of Erythrocytes in Mice Bearing Benzo(a) Pvrene — Induced Fibrosarcoma

1984 ◽  
Vol 39 (1-2) ◽  
pp. 198-200 ◽  
Author(s):  
M. R. Ray ◽  
J. Roy Chowdhury
Keyword(s):  
Life Span ◽  
Marked Reduction ◽  
Osmotic Fragility ◽  
Tumor Burden ◽  
Red Cell ◽  
Erythrocyte Survival ◽  
Hypotonic Hemolysis ◽  
Red Cell Survival ◽  
Survival Studies

Abstract Erythrocyte Survival. Osmotic Fragility, Fibrosarcom a Red cell survival studies in mice with benzo(a) pyrene [B(a)p]-induced fibrosarcoma indicate marked reduction in RBC 51Cr rW2. In contrast, the t w2 of erythrocytes from B(a)p injected but tumor-free mice was not declined. Increasing tumor burden resulted in increment in the severity of this disorder, and preincubation of normal red cells with tumor supernatant caused significant reduction (p < 0.05) in 51Cr t > /2 . It is suggested that the observed alteration in RBC life span may be due to the effect of tumor. Apparently, both intrinsic and extrinsic cellular defects could be implicated for this abnormality. However, the shortened survival cannot be attributed to altered osmotic fragility, since the erythrocytes of the fibro-sarcomatous mice were more resistant to hypotonic hemolysis in vitro.

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