Adequacy of lymph node harvest following colectomy for obstructed and nonobstructed colon cancer

2020 ◽  
Author(s):  
Arash Azin ◽  
Dhruvin H. Hirpara ◽  
Arman Draginov ◽  
Mohammadali Khorasani ◽  
Sunil V. Patel ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Lymph Node ◽  
Lymph Node Harvest

Su1765 A Comparison of Lymph Node Harvest Following Emergent Laparoscopic Versus Open Colectomy for Colon Cancer: Results From the ACS-NSQIP Database

2016 ◽  
Vol 150 (4) ◽  
pp. S1222
Author(s):  
Jad Abou Khalil ◽  
Ebram Salama ◽  
Philip Gordon ◽  
Carol-Ann Vasilevsky ◽  
Gabriella Ghitulescu ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Lymph Node ◽  
Open Colectomy ◽  
Lymph Node Harvest ◽  
Acs Nsqip ◽  
Acs Nsqip Database

Omission of Adjuvant Chemotherapy Is Associated With Increased Mortality in Patients With T3N0 Colon Cancer With Inadequate Lymph Node Harvest

2017 ◽  
Vol 60 (1) ◽  
pp. 15-21 ◽  
Author(s):  
Katerina O. Wells ◽  
Alexander T. Hawkins ◽  
Devi M. Krishnamurthy ◽  
Sekhar Dharmarajan ◽  
Sean C. Glasgow ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Lymph Node ◽  
Adjuvant Chemotherapy ◽  
Lymph Node Harvest

Lymph Node Harvest in Emergent versus Elective Colon Resections

2012 ◽  
Vol 78 (10) ◽  
pp. 1049-1053 ◽  
Author(s):  
Aaron Lewis ◽  
Gabriel Akopian ◽  
Sharon Carillo ◽  
Howard S. Kaufman
Keyword(s):  
Colon Cancer ◽  
Lymph Node ◽  
Demographic Data ◽  
Tumor Location ◽  
Colon Resection ◽  
Memorial Hospital ◽  
Harvest Lymph Node ◽  
Term Survival ◽  
Lymph Node Harvest ◽  
Emergent Surgery

Quality measures for prognostication of colon cancer include the removal of 12 or more lymph nodes during colon resection. The purpose of this study was to determine whether emergent surgery is associated with inadequate lymph node harvest. The National Cancer Database (NCDB) was queried for colon cancer patients operated on at Huntington Memorial Hospital, Pasadena, California, from 2005 to 2010. Demographic data, indication for surgery, surgeon, stage, lymph node harvest, tumor location, method of surgery, chemotherapy use, and survival were recorded. Univariate analyses were performed to compare lymph node harvest with the variables listed. Three hundred fifty-three patients underwent colon resection between 2005 and 2010. Two hundred ninety-six patients with Stage I to III disease underwent 253 elective (85%) and 43 emergent (15%) colectomies. There was no statistical difference between rates of adequate lymph node harvest in emergent and elective patient groups (86.0 vs 88.1%, P = 0.7). Inferior long-term survival was associated with emergent indication and inferior lymph node harvest. Lymph node harvest adequacy showed a gradual increase over time from 79.5 per cent in 2005 to 95.5 per cent in 2010. Despite a perception that emergent surgery is associated with inadequate lymphadenectomy, 5-year data from Huntington Memorial Hospital participation in NCDB does not suggest inferior lymph node harvests in patients operated on for obstruction or perforation.

Lymph Node Harvest in Colon Cancer: Influence of Microsatellite Instability and Proximal Tumor Location

2009 ◽  
Vol 33 (12) ◽  
pp. 2695-2703 ◽  
Author(s):  
Kjetil Søreide ◽  
Bjørn Steinar Nedrebø ◽  
Jon Arne Søreide ◽  
Aida Slewa ◽  
Hartwig Kørner
Keyword(s):  
Colon Cancer ◽  
Lymph Node ◽  
Microsatellite Instability ◽  
Tumor Location ◽  
Lymph Node Harvest

Does Obesity Influence Lymph Node Harvest among Patients Undergoing Colectomy for Colon Cancer?

2008 ◽  
Vol 74 (11) ◽  
pp. 1073-1077 ◽  
Author(s):  
Amir A. Damadi ◽  
Lucas Julien ◽  
Rodrigo Arrangoiz ◽  
Manish Raiji ◽  
David Weise ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Correlation Coefficients ◽  
Sigmoid Colectomy ◽  
Obese Patients ◽  
Lymph Node Harvest ◽  
Significant Difference ◽  
The Mean ◽  
Nonobese Patients

Adequate lymph node harvest among patients undergoing colectomy for cancer is critical for staging and therapy. Obesity is prevalent in the American population. We investigated whether lymph node harvest was compromised in obese patients undergoing colectomy for cancer. Medical records of patients who had undergone colectomy for colon cancer were reviewed. We correlated the number of lymph nodes with body mass index (BMI) and compared the number of lymph nodes among patients with BMI less than 30 kg/m2 to those with BMI of 30 kg/m2 or greater (“obese”). Among all 191 patients, the correlation coefficient was 0.04 (P > 0.2). The mean number of nodes harvested from 122 nonobese patients was 12.4 ± 6 and that for 69 obese patients 12.8 ± 6 (P > 0.2). Among 130 patients undergoing right colectomy and 35 patients undergoing sigmoid colectomy, the correlation coefficients were 0.02 (P > 0.2) and 0.16 (P > 0.2), respectively. There was not a statistically significant difference in lymph node harvest between obese and nonobese patients (14.1 ± 7 vs 13.8 ± 6, P > 0.2; and 11.8 ± 6 vs 8.6 ± 5, P > 0.2), respectively. Obesity did not compromise the number of lymph nodes harvested from patients undergoing colectomy for colon cancer.

Does body mass index affect lymph node retrieval in colon resection for cancer?

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 13571-13571 ◽  
Author(s):  
J. M. Pimiento ◽  
M. A. Cristancho ◽  
K. Aboulhosn ◽  
T. Fancher ◽  
J. A. Palesty ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Colon Cancer ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Body Mass ◽  
Colon Resection ◽  
Fatty Tissue ◽  
Specimen Length ◽  
Lymph Node Harvest ◽  
Lymph Node Retrieval

13571 Background: The management of colon cancer is a multidisciplinary effort that begins with adequate staging centered around the assessment of lymphatic spread. Multiple research groups have studied the number of lymph nodes retrieved and its relation with the outcome of patients with colon cancer, reporting better outcome in patients with a higher number of nodes retrieved. It has been well established that fatty tissue makes lymph node recovery difficult.Our objective was to evaluate if Body Mass Index (BMI) is associated with the number of lymph nodes retrieved, age, stage or location of the tumor. Methods: Retrospective chart review of patient who underwent colon resection for cancer between January 2001 to January 2005. Demographics, BMI and pathologic findings were recorded. Results: 395 patients had diagnosis of colon cancer, 140 underwent surgical procedures for these malignancies. Only 127 patients had complete records. The average age was 72 years. The average lymph node retrieval was 11.4. There was a significant relation between nodes harvested and specimen length (p 0.0028), age (p 0.0011), and stage IV cancer (p 0.002). There was no significant relationship between lymph node retrieval and BMI (p 0.1), location of the tumor (p 0.6) or stage I, II or III. Conclusion: We did not find any statistically significant correlation between BMI and lymph node retrieval, confirming reports that indicate the necessity of adequate lymph node harvest in patients with colon cancer for adequate staging and treatment. This may be because this study was done at a non-specialized center and because the operations were done by a number of different surgeons and the histopathology by numerous pathologists. The relation of improved lymph node harvest with greater specimen length supports other studies that point toward surgical and pathologic techniques as the most important factors in the appropriate staging of colon cancers. Hence, standardized surgical and histopathologic techniques need to be employed for harvesting adequate numbers of lymph nodes in resection specimens because number of nodes is critical to therapy, and an insufficient numbers of nodes may have a detrimental impact on colon cancer patient outcome. A prospective study should be performed in order to confirm the results of this study. No significant financial relationships to disclose.

scholarly journals Lymph node harvest as a marker of quality in colon cancer resection: A comparison between laparoscopic and open resections

2012 ◽  
Vol 10 (8) ◽  
pp. S27
Author(s):  
Angus Kaye ◽  
Nicola Wright ◽  
Nagy Rizkalla ◽  
Emma Hamilton ◽  
Graham Williams ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Lymph Node ◽  
Cancer Resection ◽  
Lymph Node Harvest ◽  
Colon Cancer Resection

scholarly journals Number of Intratumoral T Lymphocytes Is Associated With Lymph Node Size, Lymph Node Harvest, and Outcome in Node-Negative Colon Cancer

2016 ◽  
Vol 145 (6) ◽  
pp. 826-836 ◽  
Author(s):  
Bruno Märkl ◽  
Johanna Wieberneit ◽  
Hallie Kretsinger ◽  
Patrick Mayr ◽  
Matthias Anthuber ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Lymph Node ◽  
T Lymphocytes ◽  
Node Negative ◽  
Lymph Node Harvest ◽  
Lymph Node Size ◽  
Node Size

Risk factors associated with poor lymph node harvest after colon cancer surgery in a national cohort

2013 ◽  
Vol 15 (6) ◽  
pp. e301-e308 ◽  
Author(s):  
B. S. Nedrebø ◽  
K. Søreide ◽  
A. Nesbakken ◽  
M. T. Eriksen ◽  
J. A. Søreide ◽  
...  
Keyword(s):  
Risk Factors ◽  
Colon Cancer ◽  
Lymph Node ◽  
Cancer Surgery ◽  
Lymph Node Harvest ◽  
Factors Associated ◽  
National Cohort ◽  
Colon Cancer Surgery

Predictors of adequate lymph node harvest during colectomy for colon cancer

2019 ◽  
Vol 218 (1) ◽  
pp. 113-118 ◽  
Author(s):  
Jeffrey Douaiher ◽  
Tanvir Hussain ◽  
Sean J Langenfeld
Keyword(s):  
Colon Cancer ◽  
Lymph Node ◽  
Lymph Node Harvest ◽  
Adequate Lymph Node
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