Outcomes of neoadjuvant chemotherapy before CRS‐HIPEC for patients with appendiceal cancer

2020 ◽  
Vol 122 (3) ◽  
pp. 388-398
Author(s):  
JC Chen ◽  
Eliza W. Beal ◽  
John Hays ◽  
Timothy M. Pawlik ◽  
Sherif Abdel‐Misih ◽  
...  
Keyword(s):  
Neoadjuvant Chemotherapy ◽  
Appendiceal Cancer

scholarly journals Surgical Resection with Neoadjuvant Chemotherapy for Locoregionally Recurrent Appendiceal Cancer Invading the External Iliac Vessels

2018 ◽  
Vol 2018 ◽  
pp. 1-6
Author(s):  
Jun Takahashi ◽  
Shingo Tsujinaka ◽  
Nao Kakizawa ◽  
Noriya Takayama ◽  
Erika Machida ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Surgical Resection ◽  
Ileocecal Resection ◽  
Pelvic Cavity ◽  
Recurrent Colorectal Cancer ◽  
Appendiceal Cancer ◽  
En Bloc ◽  
One Year ◽  
The Right

Recent advancements in multimodal therapy can provide oncologic benefits for patients with recurrent colorectal cancer. This report presents a case of locoregionally recurrent appendiceal cancer treated with neoadjuvant chemotherapy followed by surgical resection with vascular reconstruction. A 68-year-old Japanese woman was diagnosed with appendiceal cancer and underwent ileocecal resection. The pathological evaluation revealed KRAS-mutant adenocarcinoma with the final stage of T4bN1M0. She received oral fluorouracil-based adjuvant chemotherapy. One year later, she was found to have peritoneal dissemination in the pelvic cavity and vaginal metastasis. She received an oxaliplatin-based chemotherapy followed by surgical resection. One year after the second surgery, she developed a locoregional recurrence involving the right external iliac vessels and small intestine. She received an irinotecan-based regimen with bevacizumab as neoadjuvant chemotherapy, followed by surgical resection. At first, a femoro-femoral bypass was made to secure the blood supply to the right lower extremities. Subsequently, an en bloc resection including the recurrent tumor and the external iliac vessels was completed. Surgical resection for recurrent colorectal cancer is often technically challenging because of the tumor location and invasion to adjacent organs. In this case, a surgical approach with persistent chemotherapy achieved oncologic resection of locoregionally recurrent appendiceal cancer.

Assessment of Neoadjuvant Chemotherapy on Operative Parameters and Outcome in Patients with Peritoneal Dissemination from High-Grade Appendiceal Cancer

2013 ◽  
Vol 20 (4) ◽  
pp. 1068-1073 ◽  
Author(s):  
Keli M. Turner ◽  
Nader N. Hanna ◽  
Yue Zhu ◽  
Ajay Jain ◽  
Susan B. Kesmodel ◽  
...  
Keyword(s):  
Neoadjuvant Chemotherapy ◽  
Peritoneal Dissemination ◽  
High Grade ◽  
Appendiceal Cancer

1317: Significance of Lymph Node Positive Disease in Patients Treated with Neoadjuvant Chemotherapy: Is Adjuvant Chemotherapy Beneficial?

2005 ◽  
Vol 173 (4S) ◽  
pp. 358-358
Author(s):  
Wassim Kassouf ◽  
Dan Leibovici ◽  
Xian Zhou ◽  
Colin P.N. Dinney ◽  
G.H. Barton ◽  
...  
Keyword(s):  
Lymph Node ◽  
Adjuvant Chemotherapy ◽  
Neoadjuvant Chemotherapy ◽  
Node Positive ◽  
Node Positive Disease ◽  
Lymph Node Positive
Sign in / Sign up

Export Citation Format

Share Document