Oncoplastic breast‐conserving surgery using chest wall perforator flaps: Three‐dimensional quantitative analysis of the percentage of breast volume excised and changes over time in flap volume

2019 ◽  
Vol 121 (2) ◽  
pp. 216-223
Author(s):  
Hiroshi Fujimoto ◽  
Nobumitsu Shiina ◽  
Takeshi Nagashima ◽  
Takafumi Sangai ◽  
Junta Sakakibara ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Chest Wall ◽  
Three Dimensional ◽  
Breast Conserving Surgery ◽  
Breast Volume ◽  
Perforator Flaps ◽  
Changes Over Time ◽  
Over Time

scholarly journals Chest wall perforator flaps for partial breast reconstruction: Surgical outcomes from a multicenter study

2020 ◽  
Vol 47 (2) ◽  
pp. 153-159 ◽  
Author(s):  
Soni Soumian ◽  
Rishikesh Parmeshwar ◽  
Mihir Chandarana ◽  
Sekhar Marla ◽  
Sankaran Narayanan ◽  
...  
Keyword(s):  
Breast Reconstruction ◽  
Chest Wall ◽  
Surgical Outcomes ◽  
Breast Conserving Surgery ◽  
Patient Reported Outcome Measures ◽  
Perforator Flaps ◽  
Lateral Thoracic Artery ◽  
Patient Reported ◽  
Artery Perforator

Background Perforator artery flaps based on the branches of intercostal arteries and lateral thoracic artery can be used for reconstruction after breast-conserving surgery (BCS). Although described more than a decade ago, these have not been adopted widely in clinical practice. We report on short-term and long-term surgical outcomes of partial breast reconstruction using chest wall perforator flaps from a prospective multicenter audit.Methods All patients operated for BCS and partial breast reconstruction using intercostal artery perforator or lateral thoracic artery perforator flaps from January 2015 to October 2018 were included in the analysis. Oncoplastic breast surgeons with appropriate level of training performed all tumor excisions and reconstructions as a single-stage procedure. Patient characteristics, treatment details and surgical outcomes were noted. Specific outcomes recorded were margin re-excision and complication rates.Results One hundred and twelve patients underwent the procedure in the given study period. The median age was 54 years. Median specimen weight was 62.5 g and median volume of excision was 121.4 mL. Fifteen patients (13.39%) underwent a margin re-excision for close or positive margins without additional morbidity. One patient required a completion mastectomy. Eight patients (7.14%) had an early complication. None of the patients required a contralateral symmetrization procedure. The results were comparable across the participating centers.Conclusions Chest wall artery perforator-based flaps are an excellent option for lateral and inferior quadrant partial breast reconstructions. The short and long-term surgical outcomes are comparable across sites and can be performed with minimal morbidity. Patient-reported outcome measures need to be studied.

scholarly journals A comparison of volume and anthropometric breast measurements using the Crisalix and VECTRA XT 3-dimensional surface imaging systems in women who have undergone breast-conserving surgery

2021 ◽  
Vol 9 (4) ◽  
Author(s):  
Astrid MBChB ◽  
Rachel Connell ◽  
Stephanie Dean ◽  
Rosa Micco ◽  
Naser Alotaibi ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Breast Conserving Surgery ◽  
Observer Agreement ◽  
Surface Imaging ◽  
Breast Volume ◽  
Limits Of Agreement ◽  
Sternal Notch ◽  
3 Dimensional ◽  
The Mean ◽  
Dimensional Surface

Introduction Three-dimensional surface imaging (3D-SI) of the breasts enables the measurement of anthropometric distances and breast volume. These measurements may be used in surgical planning and to facilitate clear communication with patients. The aim of this study was to compare measurements using a portable 3D-SI system, Crisalix, with a more established non-mobile camera, the VECTRA XT. Methods Participants were imaged three times using the Crisalix and the VECTRA XT system. Breast volume, sternal notch to nipple distance, nipple to nipple distance and breast width were measured. Intra-observer agreement was measured using the co-efficient of variation (CV). Agreement between the two methods was represented with Bland Altman agreement plots. Results Intra-method variation was low for both methods (maximum CV 3.3% for Crisalix and 3.2% for VECTRA XT), with only nipple-to-nipple distance being statistically significant, marginally in favour of VECTRA. The mean inter-method differences were small but the limits of agreement (LoA) were wide for all parameters: best for sternal notch to nipple distance, mean difference (MD) -0.03cm and LoA 1.8 to -1.8cm; the widest LoA were for breast volume: MD 31.1cm3 and LoA 286.7 to -244.6cm3. Conclusion This is the first comparison of anthropometric distances and breast volume measured using the two most widely used 3D-SI systems, Crisalix and VECTRA XT. Intra-method variation is low but currently it would not be appropriate to use the two systems interchangeably due to the wide limits of agreement for all four parameters assessed.

Localization and quantitative analysis of Cx43 in porcine oocytes during in vitro maturation

Zygote ◽  
2015 ◽  
Vol 24 (3) ◽  
pp. 364-370 ◽  
Author(s):  
Seunghoon Lee ◽  
Yuuki Hiradate ◽  
Yumi Hoshino ◽  
Yeoung-gyu Ko ◽  
Kentaro Tanemura ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Western Blotting ◽  
In Vitro Maturation ◽  
Time Course ◽  
Junction Protein ◽  
Porcine Oocyte ◽  
Gap Junction Protein ◽  
Changes Over Time ◽  
Over Time

SummaryMany studies of the main gap junction protein, Cx43, have been conducted in porcine oocyte research, but they have been limited to investigations of cumulus–oocyte complexes (COCs). In this study, we verified Cx43 not in COCs, but in porcine oocytes during maturation, and conducted a quantitative time course analysis. The location and dynamics of Cx43 were examined by immunocytochemistry and western blotting, respectively. COCs were cultured in NCSU23 medium and processed for immunocytochemistry and western blotting at 0, 14, 28, and 42 h after denuding. A Cx43 signal was detected on oolemmas, transzonal projections and the surface of zona pellucidae. Western blotting showed that Cx43 band density increased from 0 to 14 h, and gradually decreased thereafter. Our results clarified that Cx43 is localized in the ooplasmic membrane through zona pellucidae and its level changes over time during culture in porcine oocytes.

scholarly journals In-flight calibration of the Hot Ion Analyser on board Cluster

2014 ◽  
Vol 3 (1) ◽  
pp. 49-58 ◽  
Author(s):  
A. Blagau ◽  
I. Dandouras ◽  
A. Barthe ◽  
S. Brunato ◽  
G. Facskó ◽  
...  
Keyword(s):  
High Frequency ◽  
Detection Efficiency ◽  
Radiation Detector ◽  
Three Dimensional ◽  
High Sensitivity ◽  
Relaxation Experiment ◽  
Cluster Ion ◽  
Low Sensitivity ◽  
Changes Over Time ◽  
Over Time

Abstract. The Hot Ion Analyser (HIA), part of the Cluster Ion Spectrometry experiment, has the objective to measure the three-dimensional velocity distributions of ions. Due to a variety of factors (exposure to radiation, detector fatigue and aging, changes in the operating parameters, etc.), the particles' detection efficiency changes over time, prompting for continuous in-flight calibration. This is achieved by comparing the HIA data with the data provided by the WHISPER (Waves of HIgh frequency and Sounder for Probing of Electron density by Relaxation) experiment on magnetosheath intervals, for the high-sensitivity section of the instrument, or solar wind intervals, for the low-sensitivity section. The paper presents in detail the in-flight calibration methodology, reports on the work carried out for calibrating HIA and discusses plans to extend this activity in order to ensure the instrument's highest data accuracy.

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