“Tumor budding and adjacent tissue at the invasive front correlate with delayed neck metastasis in clinical early‐stage tongue squamous cell carcinoma”

2019 ◽  
Vol 121 (2) ◽  
pp. 413-413
Author(s):  
Pallvi Kaul ◽  
Dharma R. Poonia
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Tongue Squamous Cell Carcinoma ◽  
Tumor Budding ◽  
Invasive Front ◽  
Neck Metastasis ◽  
Adjacent Tissue

scholarly journals Tumor budding and depth of invasion can be used as prognostic risk factors in determining treatment plan for early stage oral squamous cell carcinoma

2019 ◽  
Vol 7 (10) ◽  
pp. 3854
Author(s):  
Kaduganoor Ramakrishnan Mohan ◽  
Rahamathulla Mudassar Sharief ◽  
Rahila C.
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Treatment Plan ◽  
Tumor Budding ◽  
Grading System ◽  
Depth Of Invasion ◽  
Invasive Front

Background: The grading of oral squamous cell carcinoma can be useful along with TNM staging in determining treatment plan. The aim is to evaluate the prognostic value of histopathological grading of oral squamous cell carcinoma and to find its importance in setting appropriate treatment plan.Methods: The study includes 60 oral squamous cell carcinoma cases surgically operated during January 2012 to December 2018. From the archival paraffin blocks and available resected specimens of each case, the histological parameters used in Bryne’s invasive grading system and Almangush BD model were evaluated and compared to their prognosis.Results: The parameters used in BD model-tumor budding and depth of invasion were found to be statistically significant with prognosis of the disease. Except for nuclear polymorphism, the parameters used in Bryne’s invasive front grading system do not correlate with prognosis.Conclusion: Based on the prognostic significance, tumor budding ≥5 buds in the invasive front area and depth of invasion ≥4mm can be used as risk factors in prospective clinical trials by considering them in early stage disparity cases for multimodality treatment approach and elective neck dissection.

Tumor budding as a novel predictor of occult metastasis in cT2N0 tongue squamous cell carcinoma

2018 ◽  
Vol 76 ◽  
pp. 1-8 ◽  
Author(s):  
Junki Sakata ◽  
Keisuke Yamana ◽  
Ryoji Yoshida ◽  
Yuichiro Matsuoka ◽  
Kenta Kawahara ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tongue Squamous Cell Carcinoma ◽  
Tumor Budding ◽  
Occult Metastasis

scholarly journals Tumor budding score predicts lymph node status in oral tongue squamous cell carcinoma and should be included in the pathology report

PLoS ONE ◽  
2020 ◽  
Vol 15 (9) ◽  
pp. e0239783
Author(s):  
Inger-Heidi Bjerkli ◽  
Helene Laurvik ◽  
Elisabeth Sivy Nginamau ◽  
Tine M. Søland ◽  
Daniela Costea ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tongue Squamous Cell Carcinoma ◽  
Tumor Budding ◽  
Lymph Node Status ◽  
Pathology Report ◽  
Oral Tongue ◽  
Node Status
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