The role of adjuvant chemotherapy in stage II and III mucinous colon cancer

2019 ◽  
Vol 120 (7) ◽  
pp. 1190-1200 ◽  
Author(s):  
Adam C. Fields ◽  
Pamela Lu ◽  
Joel Goldberg ◽  
Jennifer Irani ◽  
Ronald Bleday ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Adjuvant Chemotherapy ◽  
Stage Ii

scholarly journals Adjuvant Chemotherapy for Stage II Colon Cancer

Cancers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2584
Author(s):  
Sara Elena Rebuzzi ◽  
Guido Pesola ◽  
Valentino Martelli ◽  
Alberto Felice Sobrero
Keyword(s):  
Colon Cancer ◽  
Adjuvant Chemotherapy ◽  
Therapeutic Benefit ◽  
Stage Ii ◽  
Current Evidence ◽  
Decision Algorithm ◽  
Cancer Management ◽  
Relative Contribution ◽  
Stage Ii Colon Cancer

In stage II colon cancer management, surgery alone has shown a high cure rate (about 80%), and the role of adjuvant chemotherapy is still a matter of debate. Patients with high-risk features (T4, insufficient nodal sampling, grading, etc.) have a poorer prognosis and, usually, adjuvant chemotherapy is recommended. The purpose of the present study is to highlight and discuss what is still unclear and not completely defined from the previous trials regarding risk stratification and therapeutic benefit of adjuvant chemotherapy. With all the limitations of generalizing, we make the effort of trying to quantify the relative contribution of each prognostic factor and the benefit of adjuvant chemotherapy for stage II colon cancer. Finally, we propose a decision algorithm with the aim of summarizing the current evidence and translating it to clinical practice.

Prognostic significance of K- ras and TP53 mutations in the role of adjuvant chemotherapy on survival in patients with dukes C colon cancer

2001 ◽  
Vol 44 (3) ◽  
pp. 358-363 ◽  
Author(s):  
W. A. Bleeker ◽  
V. M. Hayes ◽  
A. Karrenbeld ◽  
R. M. W. Hofstra ◽  
E. Verlind ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Adjuvant Chemotherapy ◽  
Prognostic Significance ◽  
Tp53 Mutations ◽  
Dukes C

Age Determines Adjuvant Chemotherapy Use in Resected Stage II Colon Cancer

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Brendan L. Hagerty ◽  
John G. Aversa ◽  
Dana A. Dominguez ◽  
Jeremy L. Davis ◽  
Jonathan M. Hernandez ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Adjuvant Chemotherapy ◽  
Stage Ii ◽  
Resected Stage ◽  
Stage Ii Colon Cancer

Microsatellite Status and Adjuvant Chemotherapy in Patients with Stage II Colon Cancer

2010 ◽  
Vol 6 (3) ◽  
pp. 148-157 ◽  
Author(s):  
Jean-Baptiste Bachet ◽  
Pierre Laurent-Puig ◽  
Aimery de Gramont ◽  
Thierry André
Keyword(s):  
Colon Cancer ◽  
Adjuvant Chemotherapy ◽  
Stage Ii ◽  
Stage Ii Colon Cancer

scholarly journals Analysis of the benefit of the adjuvant chemotherapy in stage II colon cancer according to the presence of classic poor risk factors: Our experience in Ramon y Cajal Hospital

2018 ◽  
Vol 29 ◽  
pp. v64
Author(s):  
C. Saavedra Serrano ◽  
M. Villamayor Delgado ◽  
E. Corral de la Fuente ◽  
A. Barquín García ◽  
J. Serrano Domingo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Colon Cancer ◽  
Adjuvant Chemotherapy ◽  
Stage Ii ◽  
Poor Risk ◽  
Stage Ii Colon Cancer ◽  
Ramón Y Cajal

Eligibility of Real-World Patients With Stage II and III Colon Cancer for Adjuvant Chemotherapy Trials

2020 ◽  
Vol 19 (4) ◽  
pp. e226-e234 ◽  
Author(s):  
Atul Batra ◽  
Shiying Kong ◽  
Winson Y. Cheung
Keyword(s):  
Colon Cancer ◽  
Adjuvant Chemotherapy ◽  
Real World ◽  
Stage Ii
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