Does intra-operative margin assessment improve margin status and re-excision rates? A population-based analysis of outcomes in breast-conserving surgery for ductal carcinoma in situ

2018 ◽  
Vol 118 (7) ◽  
pp. 1205-1211 ◽  
Author(s):  
Alison Laws ◽  
Mantaj S Brar ◽  
Antoine Bouchard-Fortier ◽  
Brad Leong ◽  
May Lynn Quan
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Breast Conserving Surgery ◽  
Population Based ◽  
Margin Status ◽  
Margin Assessment

Predictors of Local Recurrence in a Population-Based Cohort of Women with Ductal Carcinoma In Situ Treated with Breast Conserving Surgery Alone

2010 ◽  
Vol 18 (1) ◽  
pp. 119-124 ◽  
Author(s):  
Elaine S. Wai ◽  
Mary L. Lesperance ◽  
Cheryl S. Alexander ◽  
Pauline T. Truong ◽  
Patrizia Moccia ◽  
...  
Keyword(s):  
Local Recurrence ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Breast Conserving Surgery ◽  
Population Based

Evaluating the relationship between ductal carcinoma in situ, calcifications, and margin status in patients undergoing breast conserving surgery

2019 ◽  
Vol 119 (6) ◽  
pp. 694-699 ◽  
Author(s):  
Elizabeth H. Bruenderman ◽  
Neal Bhutiani ◽  
Megan K. Mercer ◽  
Kelly M. McMasters ◽  
Mary Ann G. Sanders ◽  
...  
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Breast Conserving Surgery ◽  
Margin Status ◽  
The Relationship

scholarly journals Radioactive Seed Versus Wire-Guided Localization for Ductal Carcinoma in Situ of the Breast: Comparable Resection Margins

2020 ◽  
Vol 27 (13) ◽  
pp. 5296-5302
Author(s):  
Marie Colombe Agahozo ◽  
Sofie A.M. Berghuis ◽  
Esther van den Broek ◽  
Linetta B. Koppert ◽  
Inge-Marie Obdeijn ◽  
...  
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Resection Margin ◽  
Ductal Carcinoma ◽  
Breast Conserving Surgery ◽  
Margin Status ◽  
National Cohort ◽  
Resection Margin Status ◽  
Radioactive Seed

Abstract Background There are currently two widely used methods for preoperative localization of ductal carcinoma in situ (DCIS) of the breast: wire-guided localization (WGL) and radioactive seed localization (RSL). Several studies compared these localization techniques in small cohorts. Objective The aim of this study was to compare the surgical resection margin status between RSL and WGL in a large national cohort of patients with DCIS. Patients and Methods We included patients from the Dutch Pathology Registry who underwent breast-conserving surgery for DCIS by either RSL (n = 1851) or WGL (n = 2187) between 2009 and 2019. Several clinicopathological characteristics were compared between these two groups, including resection margin status and number of re-excisions. Results Patients undergoing RSL were younger (p = 0.014) and were more often diagnosed with a large DCIS (p = 0.013), high grade DCIS (p < 0.001) and comedonecrosis (p < 0.001) compared with patients undergoing WGL. There was no significant difference in resection margin status between both groups (p = 0.089) and the number of re-excisions (p = 0.429). However, in case of re-excision, patients in the RSL group were more often treated with breast-conserving surgery (p = 0.029). Conclusion In this large national cohort study of patients with DCIS, we demonstrated that there was no difference in resection margin status between both procedures, or in the number of re-excisions, but patients in the RSL group were more often treated with breast-conserving therapy in case of a re-excision.

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