Comparison of sentinel lymph node biopsy guided by blue dye with or without indocyanine green in early breast cancer

2018 ◽  
Vol 117 (8) ◽  
pp. 1841-1847 ◽  
Author(s):  
Songjie Shen ◽  
Qianqian Xu ◽  
Yidong Zhou ◽  
Feng Mao ◽  
Jinghong Guan ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Indocyanine Green ◽  
Early Breast Cancer ◽  
Lymph Node Biopsy ◽  
Blue Dye ◽  
Node Biopsy

scholarly journals Sentinel lymph node biopsy after neoadjuvant treatment of breast cancer using blue dye, radioisotope, and indocyanine green: Prospective cohort study

2020 ◽  
Vol 59 ◽  
pp. 156-160
Author(s):  
Prakasit Chirappapha ◽  
Tanet Chatmongkonwat ◽  
Panuwat Lertsithichai ◽  
Wiriya Pipatsakulroj ◽  
Chanika Sritara ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cohort Study ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Indocyanine Green ◽  
Neoadjuvant Treatment ◽  
Lymph Node Biopsy ◽  
Blue Dye ◽  
Node Biopsy

scholarly journals Diagnostic Performance of Indocyanine Green Plus Methylene Blue Versus Radioisotope Plus Methylene Blue Dye Method for Sentinel Lymph Node Biopsy in Node-Negative Early Breast Cancer

2020 ◽  
pp. 1225-1231
Author(s):  
Sanjit Kumar Agrawal ◽  
Izideen Hashlamoun ◽  
Banira Karki ◽  
Abhishek Sharma ◽  
Indu Arun ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Methylene Blue ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Indocyanine Green ◽  
Early Breast Cancer ◽  
Diagnostic Performance ◽  
Lymph Node Biopsy ◽  
Node Biopsy

PURPOSE Sentinel lymph node biopsy (SLNB) by dual-dye method (radioisotope plus blue) is the gold standard for axillary staging in patients with breast cancer, but in developing countries, logistic issues and financial constraint play a vital role. Recently, indocyanine green (ICG) has emerged as an alternative to radioisotope (technetium-99 [Tc-99]) for SLNB in breast cancer. This study compared the diagnostic performance of Tc-99 plus methylene blue (MB) dye versus ICG + MB dye SLNB. METHODS Two hundred seven patients with early breast cancer (T1-3N0) were included in the study from 2017 to 2019. SLNB was done either with Tc-99 + MB or with ICG + MB as per availability of radioisotope. SLN identification rate (IR), SLN positivity rate, and metastatic SLN counts were compared between the 2 groups. RESULTS IR was 199 (96%) of 207. IR was 95% in Tc-99 + MB compared with 97% with ICG + MB. The mean number of SLNs identified were 3.17 (standard deviation [SD], 1.84), with > 1 SLN identified in 87% patients by Tc-99 + MB. SLN was positive in 31.3% of patients with a metastatic SLN count of 0.37 (SD, 0.76). With ICG + MB, the number of SLNs was 2.73 (SD, 1.55), with > 1 SLN identified in 79% of patients. Twenty-eight percent of patients had positive SLNs, with a metastatic SLN count of 0.41 (SD, 0.77). A sharp decline in the availability of Tc-99 was observed, with 58% of patients in 2014 and only 12% of patients in 2018. CONCLUSION ICG is equivalent to Tc-99 for SLNB in early breast cancer and has a good potential to be adopted by surgeons in resource-constrained setups.

Indocyanine green fluorescence mapping for sentinel lymph node biopsy in early breast cancer

2015 ◽  
Vol 24 (4) ◽  
pp. 375-379 ◽  
Author(s):  
Vassilis Pitsinis ◽  
Elena Provenzano ◽  
Loukas Kaklamanis ◽  
Gordon C. Wishart ◽  
John R. Benson
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Indocyanine Green ◽  
Early Breast Cancer ◽  
Lymph Node Biopsy ◽  
Green Fluorescence ◽  
Indocyanine Green Fluorescence ◽  
Node Biopsy
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