Is primary sidedness a prognostic factor in patients with resected colon cancer liver metastases (CLM)?

2018 ◽  
Vol 117 (5) ◽  
pp. 858-863 ◽  
Author(s):  
Márcio C Marques ◽  
Héber S. C. Ribeiro ◽  
Wílson L. Costa ◽  
Victor Hugo F. de Jesus ◽  
Mariana P. de Macedo ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Prognostic Factor ◽  
Liver Metastases ◽  
Colon Cancer Liver Metastases

scholarly journals Indocyanine Green Labels an Orthotopic Nude-Mouse Model of Very-Early Colon-Cancer Liver Metastases

In Vivo ◽  
2020 ◽  
Vol 34 (5) ◽  
pp. 2277-2280
Author(s):  
YOSHIHIKO TASHIRO ◽  
HANNAH M. HOLLANDSWORTH ◽  
HIROTO NISHINO ◽  
JUN YAMAMOTO ◽  
SIAMAK AMIRFAKHRI ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Mouse Model ◽  
Indocyanine Green ◽  
Liver Metastases ◽  
Nude Mouse ◽  
Nude Mouse Model ◽  
Early Colon Cancer ◽  
Colon Cancer Liver Metastases

Does primary site of colorectal cancer become a prognostic factor of patients undergoing curative resection of liver metastases?

2017 ◽  
Vol 35 (4_suppl) ◽  
pp. 772-772 ◽  
Author(s):  
Rika Kizawa ◽  
Yasushi Ichikawa ◽  
Fumitaka Kumamoto ◽  
Yu Sawada ◽  
Ryusei Matsuyama ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Colon Cancer ◽  
Liver Metastasis ◽  
Prognostic Factor ◽  
Liver Metastases ◽  
Curative Resection ◽  
Cox Regression ◽  
Univariate Analysis ◽  
Primary Site ◽  
Significant Difference

772 Background: The comparison of prognosis between right and left-sided colon cancer (RC, LC) has recently attracted a lot of attention. We examined whether primary location of colo-rectal cancer represents a prognostic factor of patients received curative resection of liver metastasis. Methods: We reviewed all patients undergoing resection of liver metastasis of colo-rectal cancer from1992 to 2013 in the 2 YCU hospitals, and selected eligible 377 patients (59 [15.6 %] with RC, 318 [84.4 %] with LC) undergoing R0 or 1 resection of primary and metastatic lesions. Patients with transverse colon cancer were excluded. We stratified patients according to previously-reported prognostic factors of hepatic metastasis resection, and conducted univariate analysis by Log Rank test to compared overall survival (OS) in each stratum. Using those results, independent factors affecting OS were determined by multivariable Cox regression. Results: The median OS of 377 patients was 66 months, and disease free survival (DFS) was 11.6 months. Univariate analysis revealed that the number and maximum diameter of liver metastasis, existence of other metastasis apart from liver, CEA, and having pre- or post- operative chemotherapy showed significant difference of OS. Primary site did not show significant difference of OS (p = 0.547), but median OS of LC (67 months) was 24 months longer than of RC. As for DFS, there was no significant difference between RC and LC (10.75 vs. 11.6 months, p = 0.873). Multivariate Cox regression analysis was conducted using former factors showing significant difference and primary site. Then primary site was an independent prognostic factor (p = 0.047). LC showed a lower risk than RC (HR: 0.675). Conclusions: The primary site did not affect DFS, but could become a prognostic factor of OS with patients undergoing curative resection of liver metastases. It suggested that curative resection of liver metastases could contribute to prolong survival, regardless of RC or LC. And there is some possibility that the primary site affects prognosis after post-operative recurrence of colo-rectal cancer liver metastases.

scholarly journals 90Y Resin Microspheres Radioembolization for Colon Cancer Liver Metastases Using Full-Strength Contrast Material

2018 ◽  
Vol 41 (9) ◽  
pp. 1419-1427 ◽  
Author(s):  
I. Kurilova ◽  
R. G. H. Beets-Tan ◽  
G. A. Ulaner ◽  
F. E. Boas ◽  
E. N. Petre ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Liver Metastases ◽  
Contrast Material ◽  
Full Strength ◽  
Resin Microspheres ◽  
Colon Cancer Liver Metastases

1053 – Uptake and Patient Outcomes of Laparoscopic Liver Resection for Colon Cancer Liver Metastases. A Populationbased Analysis

2019 ◽  
Vol 156 (6) ◽  
pp. S-1433
Author(s):  
Julian Wang ◽  
Christopher Griffiths ◽  
Marko Simunovic ◽  
Sameer Parpia ◽  
Leyo Ruo ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Liver Resection ◽  
Liver Metastases ◽  
Patient Outcomes ◽  
Laparoscopic Liver Resection ◽  
Colon Cancer Liver Metastases
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