Comparison of two novel staging systems with the TNM system in predicting stage III colon cancer survival

2018 ◽  
Vol 117 (5) ◽  
pp. 1049-1057 ◽  
Author(s):  
Richard Walker ◽  
Trevor Wood ◽  
Emily LeSouder ◽  
Michelle Cleghorn ◽  
Manjula Maganti ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Survival ◽  
Stage Iii ◽  
Tnm System ◽  
Stage Iii Colon Cancer ◽  
Staging Systems

Prediction of Recurrence in Patients with Stage III Colon Cancer Using Conventional Clinicopathological Factors and Peripheral Blood Test Data: A New Analysis with Artificial Intelligence

Oncology ◽  
2021 ◽  
Vol 99 (5) ◽  
pp. 318-326
Author(s):  
Yutaro Kamei ◽  
Tetsuro Takayama ◽  
Toshiyuki Suzuki ◽  
Kenichi Furihata ◽  
Megumi Otsuki ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Colon Cancer ◽  
Serum Albumin ◽  
Test Data ◽  
Predictive Factors ◽  
Blood Test ◽  
Stage Iii ◽  
Clinicopathological Factors ◽  
Stage Iii Colon Cancer ◽  
Staging Systems

Background: Survival rate may be predicted by tumor-node-metastasis staging systems in colon cancer. In clinical practice, about 20 to 30 clinicopathological factors and blood test data have been used. Various predictive factors for recurrence have been advocated; however, the interactions are complex and remain to be established. We used artificial intelligence (AI) to examine predictive factors related to recurrence. Methods: The study group comprised 217 patients who underwent curative surgery for stage III colon cancer. Using a self-organizing map (SOM), an AI-based method, patients with only 23 clinicopathological factors, patients with 23 clinicopathological factors and 34 of preoperative blood test data (pre-data), and those with 23 clinicopathological factors and 31 of postoperative blood test data (post-data) were classified into several clusters with various rates of recurrence. Results: When only clinicopathological factors were used, the percentage of T4b disease, the percentage of N2 disease, and the number of metastatic lymph nodes were significantly higher in a cluster with a higher rate of recurrence. When clinicopathological factors and pre-data were used, three described pathological factors and the serum C-reactive protein (CRP) levels were significantly higher and the serum total protein (TP) levels, serum albumin levels, and the percentage of lymphocytes were significantly lower in a cluster with a higher rate of recurrence. When clinicopathological factors and post-data were used, three described pathological factors, serum CRP levels, and serum carcinoembryonic antigen levels were significantly higher and serum TP levels, serum albumin levels, and the percentage of lymphocytes were significantly lower in a cluster with a higher rate of recurrence. Conclusions: This AI-based analysis extracted several risk factors for recurrence from more than 50 pathological and blood test factors before and after surgery separately. This analysis may predict the risk of recurrence of a new patient by confirming which clusters this patient belongs to.

The impact of single and multiagent chemotherapy on stage III colon cancer survival.

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e13093-e13093
Author(s):  
Aabra Ahmed ◽  
Ahmed I Tahseen ◽  
Katrina Wolfe ◽  
Ryan W Walters ◽  
Peter T. Silberstein
Keyword(s):  
Colon Cancer ◽  
Cancer Survival ◽  
Stage Iii ◽  
Stage Iii Colon Cancer ◽  
Multiagent Chemotherapy ◽  
The Impact

Prognostic factors for stage III colon cancer in patients 80 years of age and older

2021 ◽  
Vol 36 (4) ◽  
pp. 811-819
Author(s):  
Bogdan Badic ◽  
Maude Oguer ◽  
Melanie Cariou ◽  
Tiphaine Kermarrec ◽  
Servane Bouzeloc ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Prognostic Factors ◽  
Stage Iii ◽  
Stage Iii Colon Cancer

Should Total Number of Lymph Nodes be Used as a Quality of Care Measure for Stage III Colon Cancer?

2010 ◽  
Vol 251 (1) ◽  
pp. 184-185
Author(s):  
Jiping Wang ◽  
Mahmoud Kulaylat ◽  
James Hassett ◽  
Kelli Bullard Dunn ◽  
Merril Dayton ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Quality Of Care ◽  
Lymph Nodes ◽  
Stage Iii ◽  
Stage Iii Colon Cancer ◽  
Care Measure

scholarly journals Estimating the optimal rate of adjuvant chemotherapy utilization for stage III colon cancer

2019 ◽  
Vol 8 (12) ◽  
pp. 5590-5599
Author(s):  
Safiya Karim ◽  
Christopher M. Booth ◽  
Kelly Brennan ◽  
Yingwei Peng ◽  
D. Robert Siemens ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Adjuvant Chemotherapy ◽  
Optimal Rate ◽  
Stage Iii ◽  
Stage Iii Colon Cancer
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