Laparoscopic versus open surgery for rectal cancer after neoadjuvant chemoradiation: Long-term outcomes of a propensity score matched study

2017 ◽  
Vol 117 (3) ◽  
pp. 506-513 ◽  
Author(s):  
Ramakrishnan Ayloor Seshadri ◽  
Rajaraman Swaminathan ◽  
Ayyappan Srinivasan
Keyword(s):  
Rectal Cancer ◽  
Propensity Score ◽  
Open Surgery ◽  
Neoadjuvant Chemoradiation ◽  
Long Term Outcomes ◽  
Matched Study

Long-Term Outcomes After Laparoscopic Surgery Versus Open Surgery for Rectal Cancer: A Propensity Score Analysis

2013 ◽  
Vol 20 (8) ◽  
pp. 2633-2640 ◽  
Author(s):  
Jun Seok Park ◽  
Gyu-Seog Choi ◽  
Soo Han Jun ◽  
Soo Yeun Park ◽  
Hye Jin Kim
Keyword(s):  
Rectal Cancer ◽  
Laparoscopic Surgery ◽  
Propensity Score ◽  
Open Surgery ◽  
Propensity Score Analysis ◽  
Long Term Outcomes ◽  
Score Analysis

Short- and Long-term Outcomes after Robotic and Laparoscopic Liver Resection for Malignancies: A Propensity Score-Matched Study

2019 ◽  
Vol 43 (6) ◽  
pp. 1594-1603 ◽  
Author(s):  
Chetana Lim ◽  
Chady Salloum ◽  
Antonella Tudisco ◽  
Claudio Ricci ◽  
Michael Osseis ◽  
...  
Keyword(s):  
Liver Resection ◽  
Propensity Score ◽  
Laparoscopic Liver Resection ◽  
Long Term Outcomes ◽  
Short And Long Term ◽  
Matched Study

scholarly journals Management of the Complete Clinical Response

2017 ◽  
Vol 30 (05) ◽  
pp. 387-394 ◽  
Author(s):  
Guilherme São Julião ◽  
Bruna Vailati ◽  
Ivana Castro ◽  
Debora Raffaele ◽  
Angelita Habr-Gama
Keyword(s):  
Rectal Cancer ◽  
Clinical Response ◽  
Radical Surgery ◽  
Local Relapse ◽  
Neoadjuvant Chemoradiation ◽  
Complete Clinical Response ◽  
Watch And Wait ◽  
Long Term Outcomes

AbstractOrgan preservation is considered in the management of selected patients with rectal cancer. Complete clinical response observed after neoadjuvant chemoradiation for rectal cancer is one of these cases. Patients who present complete clinical response are candidates to the watch-and-wait approach, when radical surgery is not immediately performed and is offered only to patients in the event of a local relapse. These patients are included in a strict follow-up, and up of 70% of them will never be operated during the follow-up. This strategy is associated with similar oncological outcomes as patients operated on, and the advantage of avoiding the morbidity associated to the radical operation. In this article we will discuss in detail the best candidates for this approach, the protocol itself, and the long-term outcomes.

16 oral: Neoadjuvant Chemoradiation with or without Presacral Ioert Boost in Rectal Cancer: Local Impact in Long-Term Outcomes

2009 ◽  
Vol 91 ◽  
pp. S7
Author(s):  
F. Calvo ◽  
J. Serrano ◽  
C. Gonzalez ◽  
M. Gomez-Espi ◽  
E. Palacios ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Neoadjuvant Chemoradiation ◽  
Long Term Outcomes ◽  
Local Impact

scholarly journals Survival outcomes following laparoscopic vs open surgery for non-metastatic rectal cancer: a two-center cohort study with propensity score matching

2020 ◽  
Vol 8 (4) ◽  
pp. 319-325
Author(s):  
Kang-Lian Tan ◽  
Hai-Jun Deng ◽  
Zhi-Qiang Chen ◽  
Ting-Yu Mou ◽  
Hao Liu ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Laparoscopic Surgery ◽  
Survival Rate ◽  
Propensity Score ◽  
Propensity Score Matching ◽  
Open Surgery ◽  
Laparoscopic Group ◽  
Term Survival ◽  
Free Survival

Abstract Background:?> Laparoscopic surgery for rectal cancer is commonly performed in China. However, compared with open surgery, the effectiveness of laparoscopic surgery, especially the long-term survival, has not been sufficiently proved. Methods:?> Data of eligible patients with non-metastatic rectal cancer at Nanfang Hospital of Southern Medical University and Guangdong Provincial Hospital of Chinese Medicine between 2012 and 2014 were retrospectively reviewed. Long-term survival outcomes and short-term surgical safety were analysed with propensity score matching between groups. Results Of 430 cases collated from two institutes, 103 matched pairs were analysed after propensity score matching. The estimated blood loss during laparoscopic surgery was significantly less than that during open surgery (P = 0.019) and the operative time and hospital stay were shorter in the laparoscopic group (both P < 0.001). The post-operative complications rate was 9.7% in the laparoscopic group and 10.7% in the open group (P = 0.818). No significant difference was observed between the laparoscopic group and the open group in the 5-year overall survival rate (75.7% vs 80.6%, P = 0.346), 5-year relapse-free survival rate (74.8% vs 76.7%, P = 0.527), or 5-year cancer-specific survival rate (79.6% vs 87.4%, P = 0.219). An elevated carcinoembryonic antigen, <12 harvested lymph nodes, and perineural invasion were independent prognostic factors affecting overall survival and relapse-free survival. Conclusions:?> Our findings suggest that open surgery should still be the priority recommendation, but laparoscopic surgery is also an acceptable treatment for non-metastatic rectal cancer.

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