Transoral robotic surgery for carcinoma of unknown primary in the head and neck

2015 ◽  
Vol 112 (7) ◽  
pp. 697-701 ◽  
Author(s):  
Stephen Y. Kang ◽  
Peter T. Dziegielewski ◽  
Matthew O. Old ◽  
Enver Ozer
Keyword(s):  
Robotic Surgery ◽  
Head And Neck ◽  
Transoral Robotic Surgery ◽  
Unknown Primary ◽  
Carcinoma Of Unknown Primary

scholarly journals Transoral robotic surgery for the benefit of patients with head and neck cancer of unknown primary: our experience at St George’s University Hospital, London

2020 ◽  
Vol 102 (6) ◽  
pp. 442-450
Author(s):  
R Mistry ◽  
A Walker ◽  
D Kim ◽  
E Ofo
Keyword(s):  
Robotic Surgery ◽  
Head And Neck ◽  
Primary Tumour ◽  
Head And Neck Carcinoma ◽  
Transoral Robotic Surgery ◽  
Unknown Primary ◽  
Carcinoma Of Unknown Primary ◽  
Identification Rate ◽  
Base Of Tongue ◽  
Neck Carcinoma

Introduction Head and neck carcinoma of unknown primary represents 1–5% of all head and neck cancers and presents a diagnostic and therapeutic dilemma. In approximately 40% of cases, a primary tumour location remains unknown despite investigation. With advancements in our understanding of the role of high-risk human papilloma virus in head and neck cancer, transoral robotic surgery presents an option for diagnosis and therapy. Materials and methods This is a retrospective case series from a single centre. Case notes were reviewed for 28 patients who had transoral robotic surgery for head and neck carcinoma of unknown primary between May 2015 and July 2019. Results Transoral robotic surgery identified an oropharyngeal primary tumour in 19 of 28 (67.8%) patients. All oropharyngeal primaries were p16 positive. The base of tongue identification rate was 63.2%. Median length of inpatient stay postoperatively was 1.0 day. Normal oral intake resumed within 48 hours in 96% (27/28) of patients. Three patients (10.3%) suffered minor postoperative bleeds that were all managed conservatively. Discussion The base of tongue primary identification rate (63.2%) in this series is consistent with that previously reported (43–63%; 95% confidence interval). Primary tumour identification rate if a patient is p16 positive is 86.3% (19/22), with 100% of these being oropharyngeal. We suggest future investigation into p16 status as a means of stratifying patients with head and neck carcinoma of unknown primary for transoral robotic surgery. Conclusion Transoral robotic base of tongue mucosectomy (or lingual tonsillectomy) is a promising technique that offers a high yield of positive identification for the primary tumour. It is well tolerated with minimal associated morbidity. Our findings are comparable with those in the current literature.

Transoral robotic surgery for the management of head and neck squamous cell carcinoma of unknown primary

2015 ◽  
Vol 135 (10) ◽  
pp. 1051-1057 ◽  
Author(s):  
Hani Ibrahim Channir ◽  
Niclas Rubek ◽  
Hans Ulrik Nielsen ◽  
Katalin Kiss ◽  
Birgitte W Charabi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Robotic Surgery ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Transoral Robotic Surgery ◽  
Neck Squamous Cell Carcinoma ◽  
Unknown Primary ◽  
Carcinoma Of Unknown Primary

scholarly journals A systematic review on Transoral robotic surgery (TORS) for carcinoma of unknown primary origin: Has tongue base mucosectomy become indispensable?

2020 ◽  
Vol 45 (5) ◽  
pp. 732-738
Author(s):  
Stijn Weert ◽  
Johannes A. Rijken ◽  
Francesca Plantone ◽  
Elisabeth Bloemena ◽  
Marije R. Vergeer ◽  
...  
Keyword(s):  
Systematic Review ◽  
Robotic Surgery ◽  
Transoral Robotic Surgery ◽  
Tongue Base ◽  
Unknown Primary ◽  
Carcinoma Of Unknown Primary ◽  
Primary Origin ◽  
Unknown Primary Origin

scholarly journals A new paradigm for the diagnosis and management of unknown primary tumors of the head and neck: A role for transoral robotic surgery

2012 ◽  
Vol 123 (1) ◽  
pp. 146-151 ◽  
Author(s):  
Vikas Mehta ◽  
Paul Johnson ◽  
Andrew Tassler ◽  
Seungwon Kim ◽  
Robert L. Ferris ◽  
...  
Keyword(s):  
Robotic Surgery ◽  
Head And Neck ◽  
Transoral Robotic Surgery ◽  
Unknown Primary ◽  
New Paradigm ◽  
Primary Tumors ◽  
Diagnosis And Management ◽  
Unknown Primary Tumors

Narrowband Imaging for p16+ Unknown Primary Squamous Cell Carcinoma Prior to Transoral Robotic Surgery

2020 ◽  
Vol 163 (6) ◽  
pp. 1198-1201
Author(s):  
Kareem Al-Mulki ◽  
James Hamilton ◽  
Azeem S. Kaka ◽  
Brian J. Boyce ◽  
H. Michael Baddour ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Robotic Surgery ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Transoral Robotic Surgery ◽  
Unknown Primary ◽  
Inclusion Criteria ◽  
Level Of Evidence ◽  
Carcinoma Of Unknown Primary ◽  
Narrowband Imaging

Our purpose was to assess the potential utility of narrowband imaging (NBI) as a tool in diagnosing and treating unknown primary oropharyngeal squamous cell carcinoma (OPSCC) in patients prior to diagnostic resection with transoral robotic surgery (TORS). Between 2016 and March 2019, 29 patients with carcinoma of unknown primary meeting inclusion criteria were identified and treated with TORS. NBI was used preoperatively in 9 of 29 patients. A suspected tumor site was delineated by NBI in 8 of 9 patients (89%). Of the patients imaged with NBI, 8 of 9 (89%) patients had a pathologically confirmed tumor following TORS, corresponding to the same 8 suspected tumor sites identified with NBI. In contrast, a primary tumor was localized following TORS in 15 of 20 (75%) patients not evaluated with NBI. Thus, we see NBI as a potentially useful tool for the diagnosis and management of p16+ carcinoma of unknown primary. Level of Evidence: IIb

Post-operative therapy following transoral robotic surgery for unknown primary cancers of the head and neck

Oral Oncology ◽  
2017 ◽  
Vol 72 ◽  
pp. 150-156 ◽  
Author(s):  
Sapna A. Patel ◽  
Aarthi Parvathaneni ◽  
Upendra Parvathaneni ◽  
Jeffrey J. Houlton ◽  
Ron J. Karni ◽  
...  
Keyword(s):  
Robotic Surgery ◽  
Head And Neck ◽  
Operative Therapy ◽  
Transoral Robotic Surgery ◽  
Unknown Primary

scholarly journals Functional and quality-of-life outcomes of transoral robotic surgery for carcinoma of unknown primary

2014 ◽  
Vol 124 (9) ◽  
pp. 2089-2095 ◽  
Author(s):  
Kasim Durmus ◽  
Hafiz S. Patwa ◽  
Hamza N. Gokozan ◽  
Cuneyt Kucur ◽  
Theodoros N. Teknos ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Robotic Surgery ◽  
Transoral Robotic Surgery ◽  
Unknown Primary ◽  
Life Outcomes ◽  
Carcinoma Of Unknown Primary ◽  
Quality Of Life Outcomes
Sign in / Sign up

Export Citation Format

Share Document