Down-regulated SPARCL1 is associated with clinical significance in human gastric cancer

2011 ◽  
Vol 105 (1) ◽  
pp. 31-37 ◽  
Author(s):  
Ping Li ◽  
Jianxin Qian ◽  
Guanzhen Yu ◽  
Ying Chen ◽  
Ke Liu ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Clinical Significance ◽  
Human Gastric Cancer

scholarly journals Expression of immunoglobulin-like transcript (ILT)2 and ILT3 in human gastric cancer and its clinical significance

2012 ◽  
Vol 5 (4) ◽  
pp. 910-916 ◽  
Author(s):  
YI ZHANG ◽  
NAN LU ◽  
YUWEN XUE ◽  
MIN ZHANG ◽  
YINGJIE LI ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Clinical Significance ◽  
Human Gastric Cancer

Clinical significance of zinc finger E-box binding homeobox 1 (ZEB1) in human gastric cancer

2011 ◽  
Vol 106 (3) ◽  
pp. 280-285 ◽  
Author(s):  
Yoshinaga Okugawa ◽  
Yuji Toiyama ◽  
Koji Tanaka ◽  
Kohei Matsusita ◽  
Hiroyuki Fujikawa ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Clinical Significance ◽  
Zinc Finger ◽  
Human Gastric Cancer ◽  
E Box

scholarly journals IL-1R2 expression in human gastric cancer and its clinical significance

2021 ◽  
Author(s):  
Maoling Yuan ◽  
Lei Wang ◽  
Hao Huang ◽  
Yuan Li ◽  
Xiao Zheng ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Clinical Significance ◽  
Inflammatory Diseases ◽  
Interleukin 1 ◽  
Negative Regulator ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Human Gastric Cancer ◽  
Mrna Levels ◽  
Healthy Control

Background: Interleukin-1 receptor type II (IL-1R2), also known as CD121b, is a member of the IL-1 receptor family. IL-1R2 acts as negative regulator of the IL-1 system, modulating IL-1 availability for the signaling receptor. IL-1R2 is abnormally expressed in many human inflammatory diseases and cancers, and has important clinical significance. The present study was designed to investigate IL-1R2 expression in human gastric cancer (GC) tissues and the associated clinical implications. Methods: Immunohistochemistry was used to identify the clinical significance and prognostic value of IL-1R2 expression in GC tissues. We investigated IL-1R2 expression in GC tissues, cells, and serum using real-time PCR (RT-PCR) and enzyme-linked immunosorbent assay (ELISA) assays. Results: IL-1R2 was highly expressed in GC tissues, and the overall survival in patients with advanced GC and high IL-1R2 expression was significantly poorer than that in patients with advanced GC and low IL-1R2 expression. Moreover, IL-1R2 mRNA levels in GC tissues and most GC cells were higher than those in para-cancer tissues and GES1 human gastric mucosal epithelial cells. The level of plasma soluble IL-1R2 in GC patients was higher than that of the healthy control group. Conclusion: Increased IL-1R2 levels are involved in the initiation and progression of human GC, and IL-1R2 might be employed to develop immunotherapeutic approaches targeting GC.

Clinical significance of epidermal growth factor (EGF), EGF receptor, and c-erbb-2 in human gastric cancer

Cancer ◽  
1995 ◽  
Vol 75 (S6) ◽  
pp. 1418-1425 ◽  
Author(s):  
Akira Tokunaga ◽  
Masahiko Onda ◽  
Takeshi Okuda ◽  
Tadashi Teramoto ◽  
Itsuo Fujita ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Clinical Significance ◽  
Egf Receptor ◽  
Human Gastric Cancer ◽  
Epidermal Growth

scholarly journals Global circular RNA expression profile of human gastric cancer and its clinical significance

2017 ◽  
Vol 6 (6) ◽  
pp. 1173-1180 ◽  
Author(s):  
Yongfu Shao ◽  
Jinyun Li ◽  
Rongdan Lu ◽  
Tianwen Li ◽  
Yunben Yang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Clinical Significance ◽  
Expression Profile ◽  
Circular Rna ◽  
Rna Expression ◽  
Human Gastric Cancer

Clinical significance of low expression ofProstasinmRNA in human gastric cancer

2008 ◽  
Vol 98 (7) ◽  
pp. 559-564 ◽  
Author(s):  
Katsuya Sakashita ◽  
Koshi Mimori ◽  
Fumiaki Tanaka ◽  
Kouichirou Tahara ◽  
Hiroshi Inoue ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Clinical Significance ◽  
Human Gastric Cancer ◽  
Low Expression
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