The prevalence of and risk factors for four or more metastatic axillary lymph nodes in breast cancer patients undergoing sentinel node biopsy

2008 ◽  
Vol 98 (1) ◽  
pp. 21-26 ◽  
Author(s):  
M. Leidenius ◽  
L. Vaalavirta ◽  
P. Heikkilä ◽  
K. von Smitten ◽  
K. Salmenkivi
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Lymph Nodes ◽  
Sentinel Node ◽  
Cancer Patients ◽  
Sentinel Node Biopsy ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Breast Cancer Patients ◽  
Node Biopsy

Comparable Survival Between pN0 Breast Cancer Patients Undergoing Sentinel Node Biopsy and Extensive Axillary Dissection: A Report From the Korean Breast Cancer Society

2010 ◽  
Vol 28 (10) ◽  
pp. 1692-1699 ◽  
Author(s):  
Hyeong-Gon Moon ◽  
Wonshik Han ◽  
Dong-Young Noh
Keyword(s):  
Breast Cancer ◽  
Lymph Nodes ◽  
Sentinel Node ◽  
Cancer Patients ◽  
Sentinel Node Biopsy ◽  
Axillary Lymph ◽  
Breast Cancer Patients ◽  
Systemic Recurrence ◽  
Node Biopsy ◽  
Nationwide Registry

Purpose Recent studies showing survival benefit of extensive axillary lymph node dissection (ALND) in pN0 breast cancer have challenged the concept of sentinel node biopsy (SNB). In this study, the survival and recurrence after SNB alone and ALND in pN0 Korean breast cancer patients were investigated. Patients and Methods Using information from two large databases, including a Korean nationwide registry, we assessed survival relative to the extent of ALND in pN0 breast cancer patients. We also compared the survival of pN0 patients who underwent SNB alone with survival in those who underwent varying degrees of ALND. Results In an analysis of 1,607 pN0 patients from a single institution, less extensive ALND significantly increased the risks of breast cancer death and systemic recurrence but not of locoregional recurrence. These findings were validated by an analysis of nationwide registry data on 17,672 pN0 patients; patients with > 20 dissected lymph nodes had significantly better overall survival (OS) and breast cancer–specific survival (BCSS) than those with 10 to 20 or < 10 dissected lymph nodes. Patients who underwent SNB alone showed OS (hazard ratio [HR], 1.03; 9% CI, 0.08 to 1.56) and BCSS (HR, 1.15; 95% CI, 0.75 to 1.78) similar to those of patients who underwent extensive ALND (> 20 dissected lymph nodes), despite the small number of lymph nodes removed. Conclusion Extensive ALND is associated with better survival and less systemic recurrence than less extensive ALND in patients with pN0 breast cancer. However, SNB alone showed excellent survival results, similar to those of extensive ALND, supporting the long-term oncologic safety of SNB.

Different criteria for radioactive sentinel lymph nodes has different impact on sentinel node biopsy in breast cancer patients

2007 ◽  
Vol 95 (8) ◽  
pp. 635-639 ◽  
Author(s):  
Xiang-Yang Song ◽  
Xiao-Ming Yuan ◽  
Wen-Jun Chen ◽  
Tao Pan ◽  
Shu-Duo Xie ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Nodes ◽  
Sentinel Node ◽  
Cancer Patients ◽  
Sentinel Node Biopsy ◽  
Sentinel Lymph Nodes ◽  
Breast Cancer Patients ◽  
Node Biopsy
Sign in / Sign up

Export Citation Format

Share Document