Taurolidine induces apoptosis of murine melanoma cells in vitro and in vivo by modulation of the Bcl-2 family proteins

2007 ◽  
Vol 96 (3) ◽  
pp. 241-248 ◽  
Author(s):  
Bao Sheng Sun ◽  
Jiang Huai Wang ◽  
Lin Lin Liu ◽  
Shou Liang Gong ◽  
H. Paul Redmond
Keyword(s):  
Melanoma Cells ◽  
Murine Melanoma ◽  
Murine Melanoma Cells

Regulation of c-met expression in B16 murine melanoma cells by melanocyte stimulating hormone

1999 ◽  
Vol 112 (5) ◽  
pp. 623-630
Author(s):  
D. Rusciano ◽  
P. Lorenzoni ◽  
M.M. Burger
Keyword(s):  
Melanoma Cells ◽  
Parental Cell ◽  
Melanocortin Receptor ◽  
Parental Cell Line ◽  
Melanocyte Stimulating Hormone ◽  
Murine Melanoma ◽  
The One ◽  
Murine Melanoma Cells ◽  
Stimulating Hormone

B16 murine melanoma cells selected in vivo for enhanced liver metastatic ability (B16-LS9) show on the one hand an increased expression and constitutive activation of the proto-oncogene c-met (the receptor for hepatocyte growth factor/scatter factor), and on the other hand a more differentiated phenotype, when compared to the parental cell line, B16-F1. Following this observation, we have tried to establish whether there is a direct relationship between differentiation and c-met expression in B16 melanoma cells. Treatment of these cells with differentiating agents indicated that c-met expression was strongly induced by melanocyte stimulating hormone, while retinoic acid had almost no influence. c-met induction was triggered by engagement of the melanocortin receptor, cAMP elevation and PKA/PKC(α) activation, as respectively shown by the effects of ACTH, cAMP elevating agents and specific PK inhibitors. Regulation of c-met expression via the melanocortin receptor and cAMP raises the intriguing possibility that autocrine and/or paracrine mechanisms acting in vivo on this circuit might influence (through c-met expression and activation) the metastatic behavior of these tumor cells, which we have shown to be dependent on their c-met expression.

scholarly journals Docosahexaenoic acid inhibits melanin synthesis in murine melanoma cells in vitro through increasing tyrosinase degradation

2014 ◽  
Vol 35 (4) ◽  
pp. 489-495 ◽  
Author(s):  
Marie Carmel Balcos ◽  
Su Yeon Kim ◽  
Hyo-soon Jeong ◽  
Hye-young Yun ◽  
Kwang Jin Baek ◽  
...  
Keyword(s):  
Docosahexaenoic Acid ◽  
Melanoma Cells ◽  
Melanin Synthesis ◽  
Murine Melanoma ◽  
Murine Melanoma Cells

scholarly journals Bioimaging of Fluorescence-Labeled Mitochondria in Subcutaneously Grafted Murine Melanoma Cells by the “In Vivo Cryotechnique”

2014 ◽  
Vol 62 (4) ◽  
pp. 251-264 ◽  
Author(s):  
Ting Lei ◽  
Zheng Huang ◽  
Nobuhiko Ohno ◽  
Bao Wu ◽  
Takashi Sakoh ◽  
...  
Keyword(s):  
Melanoma Cells ◽  
In Vivo Cryotechnique ◽  
Murine Melanoma ◽  
Murine Melanoma Cells

scholarly journals Statins Stimulate In Vitro Membrane FasL Expression and Lymphocyte Apoptosis through RhoA/ROCK Pathway in Murine Melanoma Cells

Neoplasia ◽  
2007 ◽  
Vol 9 (12) ◽  
pp. 1078-1090 ◽  
Author(s):  
Guillaume Sarrabayrouse ◽  
Cindy Synaeve ◽  
Kevin Leveque ◽  
Gilles Favre ◽  
Anne-Françoise Tilkin-Manamé
Keyword(s):  
Melanoma Cells ◽  
Lymphocyte Apoptosis ◽  
Fasl Expression ◽  
Murine Melanoma ◽  
Murine Melanoma Cells

scholarly journals FTY720 induces apoptosis in B16F10-NEX2 murine melanoma cells, limits metastatic development in vivo, and modulates the immune system

Clinics ◽  
2013 ◽  
Vol 68 (7) ◽  
pp. 1018-1027 ◽  
Author(s):  
FV Pereira ◽  
DC Arruda ◽  
CR Figueiredo ◽  
MH Massaoka ◽  
AL Matsuo ◽  
...  
Keyword(s):  
Immune System ◽  
Melanoma Cells ◽  
Murine Melanoma ◽  
Murine Melanoma Cells ◽  
Metastatic Development
Sign in / Sign up

Export Citation Format

Share Document