Sarcomatoid differentiation as a prognostic factor for immunotherapy in metastatic renal cell carcinoma

2007 ◽  
Vol 95 (4) ◽  
pp. 317-323 ◽  
Author(s):  
Cheol Kwak ◽  
Yong Hyun Park ◽  
Chang Wook Jeong ◽  
Hyeon Jeong ◽  
Sang Eun Lee ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Prognostic Factor ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Sarcomatoid Differentiation

scholarly journals Depth of Remission is a Prognostic Factor for Survival in Patients with Metastatic Renal Cell Carcinoma

2015 ◽  
Vol 67 (5) ◽  
pp. 952-958 ◽  
Author(s):  
Viktor Grünwald ◽  
Rana R. McKay ◽  
Katherine M. Krajewski ◽  
Daniel Kalanovic ◽  
Xun Lin ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Prognostic Factor ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell

scholarly journals Corrigendum to: Perinephric invasion as a prognostic factor in non-metastatic renal cell carcinoma: analysis of a nation-wide registry program

2019 ◽  
Vol 49 (11) ◽  
pp. 1067-1067
Author(s):  
Haruki Kume ◽  
Yukio Homma ◽  
Nobuo Shinohara ◽  
Wataru Obara ◽  
Tsunenori Kondo ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Prognostic Factor ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell

MP30-20 UTILIZING PERCENTAGE OF SARCOMATOID DIFFERENTIATION AS A PROGNOSTIC FACTOR IN RENAL CELL CARCINOMA

2014 ◽  
Vol 191 (4S) ◽  
Author(s):  
Timothy Kim ◽  
Jasreman Dhillon ◽  
Hui-Yi Lin ◽  
Binglin Yue ◽  
Mayer Fishman ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Prognostic Factor ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Sarcomatoid Differentiation

Can Systemic Immune-Inflammation Index Create a New Perspective for the IMDC Scoring System in Patients with Metastatic Renal Cell Carcinoma?

2021 ◽  
pp. 1-8
Author(s):  
Fatma Bugdayci Basal ◽  
Cengiz Karacin ◽  
Irem Bilgetekin ◽  
Omur Berna Oksuzoglu
Keyword(s):  
Renal Cell Carcinoma ◽  
Prognostic Factor ◽  
Regression Model ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Cox Regression ◽  
Independent Prognostic Factor ◽  
Cox Regression Model ◽  
Kaplan Meier

Introduction: The aim of the study was to evaluate impact of the systemic immune-inflammation index (SII) on prognosis and survival within the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) score groups. Methods: The records of 187 patients with metastatic renal cell carcinoma (RCC) were reviewed retrospectively. The SII was calculated as follows: SII = Neutrophil × Platelet/Lymphocyte. The patients were categorized into 2 groups based on a median SII of 730 (×109 per 1 L) as SII low (<730) and SII high (≥730). The Kaplan-Meier method was used for survival analysis and a Cox regression model was utilized to determine independent predictors of survival. Results: The median age was 61 years (range: 34–86 years). Kaplan-Meier tests revealed significant differences in survival between the SII-low and SII-high levels (27.0 vs. 12.0 months, respectively, p < 0.001). The Cox regression model revealed that SII was an independent prognostic factor. The implementation of the log-rank test in the IMDC groups according to the SII level provided the distinction of survival in the favorable group (SII low 49.0 months vs. SII high 11.0 months, p < 0.001), in the intermediate group (SII low 26.0 vs. SII high 15.0 months, p = 0.007), and in the poor group (SII low 19.0 vs. SII high 6.0 months, p = 0.019). Conclusion: The SII was an independent prognostic factor and provided significant differences in survival for the favorable, intermediate, and poor IMDC groups. Thus, the SII added to the IMDC score may be clinically beneficial in predicting survival.

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