Chemoradiotherapy followed by surgery for squamous cell carcinoma of the thoracic esophagus with clinical evidence of adjacent organ invasion

2007 ◽  
Vol 95 (3) ◽  
pp. 261-266 ◽  
Author(s):  
Giovanni de Manzoni ◽  
Corrado Pedrazzani ◽  
Felice Pasini ◽  
Marco Bernini ◽  
Anna Maria Minicozzi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Clinical Evidence ◽  
Thoracic Esophagus ◽  
Adjacent Organ ◽  
Adjacent Organ Invasion ◽  
Organ Invasion

Role of Esophagectomy in Treatment of Esophageal Carcinoma with Clinical Evidence of Adjacent Organ Invasion

2001 ◽  
Vol 25 (3) ◽  
pp. 279-284 ◽  
Author(s):  
Toshiki Matsubara ◽  
Mamoru Ueda ◽  
Norihiro Kokudo ◽  
Takashi Takahashi ◽  
Tetsuichiro Muto ◽  
...  
Keyword(s):  
Esophageal Carcinoma ◽  
Clinical Evidence ◽  
Adjacent Organ ◽  
Adjacent Organ Invasion ◽  
Organ Invasion

scholarly journals Prognosticators and outcomes of patients with renal cell carcinoma and adjacent organ invasion treated with radical nephrectomy

2016 ◽  
Vol 34 (5) ◽  
pp. 237.e19-237.e26 ◽  
Author(s):  
Leonardo D. Borregales ◽  
Dae Y. Kim ◽  
Angie L. Staller ◽  
Wei Qiao ◽  
Arun Z. Thomas ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Radical Nephrectomy ◽  
Adjacent Organ ◽  
Adjacent Organ Invasion ◽  
Organ Invasion

Cardiac tamponade as an unusual initial presentation of squamous cell carcinoma of the esophagus

2021 ◽  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Cancer ◽  
Pericardial Effusion ◽  
Cell Carcinoma ◽  
Cardiac Tamponade ◽  
Squamous Cell ◽  
Unknown Etiology ◽  
Thoracic Esophagus ◽  
Moderate Amount ◽  
Carcinoma Of The Esophagus

Pericardial effusions leading to cardiac tamponade have previously been described with esophageal cancer. However, up to eighty percent of these cases have been reported in association with chemotherapy and radiation. Patients with esophageal cancer seldom initially present with pericardial effusion resulting from esophageal pericardial fistula (EPF). Herein, we present the case of a 62-year-old man who presented with pericardial effusion with an unknown etiology at presentation. Subsequently, the patient developed cardiac tamponade and was referred to the tertiary hospital for further evaluation. Computed tomography of the chest revealed a circumferential irregular enhancing lesion at the mid-thoracic esophagus suspecting esophageal cancer with EPF and a moderate amount of pericardial effusion. The patient underwent esophagoscopy and squamous cell carcinoma was found from the esophageal biopsy. An esophageal stent was successfully placed to conceal the perforation. Eventually, the patient died 13 days after admission complicated by refractory septic shock. This case highlights an atypical presentation of esophageal cancer and an unusual cause of cardiac tamponade.

scholarly journals Synchronous Squamous Cell Carcinoma of the Thoracic Esophagus and Hepatocellular Carcinoma.

1997 ◽  
Vol 30 (3) ◽  
pp. 759-763
Author(s):  
Goro Honda ◽  
Nobuyasu Yamasaki ◽  
Yasuyuki Shimahara ◽  
Toyotake Okanoue ◽  
Tetsuya Uehara ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Thoracic Esophagus

Induction Chemoradiotherapy for Squamous Cell Carcinoma of the Thoracic Esophagus: Impact of Increased Dosage on Long-Term Results

2005 ◽  
Vol 80 (4) ◽  
pp. 1176-1183 ◽  
Author(s):  
Giovanni de Manzoni ◽  
Corrado Pedrazzani ◽  
Ernesto Laterza ◽  
Felice Pasini ◽  
Antonio Grandinetti ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Long Term Results ◽  
Thoracic Esophagus ◽  
Induction Chemoradiotherapy

scholarly journals Morbidity following salvage esophagectomy for squamous cell carcinoma: the MD Anderson experience

2019 ◽  
Author(s):  
K G Mitchell ◽  
D B Nelson ◽  
E M Corsini ◽  
A A Vaporciyan ◽  
M B Antonoff ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Thoracic Esophagus ◽  
Trimodality Therapy ◽  
Entire Cohort ◽  
Selective Approach ◽  
Institutional Experience ◽  
Salvage Esophagectomy ◽  
Md Anderson

SUMMARY The survival advantage associated with the addition of surgical therapy in esophageal squamous cell carcinoma (ESCC) patients who demonstrate a complete clinical response to chemoradiotherapy is unclear, and many institutions have adopted an organ-preserving strategy of selective surgery in this population. We sought to characterize our institutional experience of salvage esophagectomy (for failure of definitive bimodality therapy) and planned esophagectomy (as a component of trimodality therapy) by retrospectively analyzing patients with ESCC of the thoracic esophagus and GEJ who underwent esophagectomy following chemoradiotherapy between 2004 and 2016. Of 76 patients who met inclusion criteria, 46.1% (35) underwent salvage esophagectomy. Major postoperative complications (major cardiovascular and pulmonary events, anastomotic leak [grade ≥ 2], and 90-day mortality) were frequent and occurred in 52.6% of the cohort (planned resection: 36.6% [15/41]; salvage esophagectomy: 71.4% [25/35]). Observed rates of 30- and 90-day mortality for the entire cohort were 7.9% (planned: 7.3% [3/41]; salvage: 8.6% [3/35]) and 13.2% (planned: 9.8% [4/41]; salvage: 17.1% [6/35]), respectively. In summary, esophagectomy following chemoradiotherapy for ESCC at our institution has been associated with frequent postoperative morbidity and considerable rates of mortality in both planned and salvage settings. Although a selective approach to surgery may permit organ preservation in many patients with ESCC, these results highlight that salvage esophagectomy for failure of definitive-intent treatment of ESCC may also constitute a difficult clinical undertaking in some cases.

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