Rationale for superficial injection techniques in lymphatic mapping in breast cancer patients

2004 ◽  
Vol 87 (4) ◽  
pp. 153-156 ◽  
Author(s):  
Omgo E. Nieweg ◽  
Susanne H. Estourgie ◽  
Maartje C. van Rijk ◽  
Bin. B.R. Kroon
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Lymphatic Mapping ◽  
Breast Cancer Patients ◽  
Injection Techniques

Where to look for sentinel node in breast cancer?

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 2560-2560
Author(s):  
Anton J. Scharl ◽  
Andreas Düran ◽  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Node ◽  
Cancer Patients ◽  
Lymphatic Mapping ◽  
False Negative ◽  
False Negative Rate ◽  
Breast Cancer Patients ◽  
Standard Methods

2560 Background: It has been observed, that the caudal Axilla on the border to pectoralis muscle is predicive for the sentinel node. The sono-morphology of lymph nodes has been the subject of multiple publications, usually dealing with malignant melanoma. In the context of sentinel lymph node biopsy (SLNB) in breast cancer patients, the following study examines the feasibility of the sonographic differentiation of the Sentinel lymph node (SLN) from neighboring non-SLNs and whether sentinel-ultrasound-needle localization (SUN) is a useful addition or alternative to current methods of “lymphatic mapping”. Methods: During a prospective study performed from 1/2003 to 9/2005 including 404 breast cancer patients (Tis-T4), the SLNB was performed using patent blue+/- 99Tc-Nanocoll. In addition to and independent of this method, the axilla was sonographically examined for “reactive” lymph nodes n=180 pt. (Siemens Elegra 7.5 MHz). The “reactivity” of the nodes was quantified using an index , which allowed the comparison of adjacent nodes. The most “reactive” lymph node in the caudal axilla was identified as the “Ultrasound-Sentinel-Node”(US-SLN) and has been marked with a wire. Results: In 180 patients the SLN was localized using the standard methods as well as (SUN). The was no difference in detection rates of US-SLN and the standard methods in tumor-free nodes(SLN-). However, for patients with axillary metastases (SLN+) SUN provided superior detection rate (99,1%). The false-negative-rate was reduced from 10,7 % to 1,3%. This was attributed to the embolization of lymph vessels afferent to the metastasized (SLN+) node causing a bypass of the “lymphatic mapping” and inhibiting detection. Conclusions: The SUN–Method is comparable to “lymphatic mapping” in tumor free nodes (SLN -). If SLN is metastasized (SLN+) - SUN is superior to the standard methods in sensitivity and specificity (80%) and the false-negative-rate can be reduced. Systematic axilla sonography is an effective method for the SLN-Localisation, and offers an excellent method for quality control during SLNB.

The Safety of Lymphatic Mapping in Pregnant Breast Cancer Patients Using Tc-99m Sulfur Colloid

2004 ◽  
Vol 10 (6) ◽  
pp. 492-495 ◽  
Author(s):  
Angela Keleher ◽  
Richard Wendt ◽  
Ebrahim Delpassand ◽  
Anne Marie Stachowiak ◽  
Henry M. Kuerer
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Lymphatic Mapping ◽  
Breast Cancer Patients ◽  
Sulfur Colloid
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