Omega‐3‐richIsochrysissp. biomass enhances brain docosahexaenoic acid levels and improves serum lipid profile and antioxidant status in Wistar rats

2019 ◽  
Vol 99 (13) ◽  
pp. 6066-6075 ◽  
Author(s):  
Jeyakumar Balakrishnan ◽  
Sugasini Dhavamani ◽  
Selvam Govindan Sadasivam ◽  
Muthu Arumugam ◽  
Sampathrajan Vellaikumar ◽  
...  
Keyword(s):  
Docosahexaenoic Acid ◽  
Lipid Profile ◽  
Serum Lipid ◽  
Antioxidant Status ◽  
Wistar Rats ◽  
Serum Lipid Profile ◽  
Omega 3

Effects of changing omega-6 to omega-3 fatty acid ratios in corn–soybean meal-based diet on performance, serum lipid profile and colostrum and milk composition of sows and performance of piglets

2019 ◽  
Vol 59 (7) ◽  
pp. 1235 ◽  
Author(s):  
Santi Devi Upadhaya ◽  
Jiao Yang ◽  
Kwang Yong Lee ◽  
In Ho Kim
Keyword(s):  
Fatty Acid ◽  
Lipid Profile ◽  
Soybean Meal ◽  
Serum Lipid ◽  
Nutrient Digestibility ◽  
Serum Lipid Profile ◽  
Omega 3 ◽  
Omega 3 Fatty Acid ◽  
Omega 6 ◽  
Dietary Treatments

This study aimed to test the effects of changing omega-6 to omega-3 fatty acid (FA) ratios in corn–soybean meal-based diet on performance, serum lipid profile and colostrum and milk nutrient contents of lactating sows as well as performance of suckling piglets. In total, 32 multiparous sows (Landrace × Yorkshire) were randomly allocated into one of four dietary treatments with eight replicates per treatment. The treatment diets were fed 7 days before farrowing until weaning. The omega-3 FA used in the experiment was from linseed oil and was coated using a spray-drying method. The dietary treatments consisted of control (CON, corn–soybean meal-based basal diet with omega-6:omega-3 FA ratios of 25:1), and basal diets (CON) containing omega-6: omega-3 FA ratios at 20:1, 15:1 and 10:1 levels. Inclusion of omega-6 and omega-3 FA at different ratios in the feed did not affect (P > 0.05) the performance, nutrient digestibility and milk nutrient composition of sows. The concentrations of high-density lipid cholesterol (HDL-C) increased (P < 0.05) and the low-density lipid cholesterol (LDL-C) tended to be reduced (P = 0.08) at weaning for sows fed 10:1 omega 6:omega-3 ratio diet. The bodyweights (BW) and average daily gains (ADG) of piglets born from sows fed 10:1 omega-6:omega-3 FA diet were greater (P < 0.05) at Week 3 and overall respectively. The BW of piglets raised from sows fed all treatment diets were heavier (P < 0.05) at Week 4 (weaning) than those in the CON. Positive correlations between dietary omega-6:omega-3 FA ratio and serum HDL-C concentrations and a negative correlations between dietary omega-6:omega-3 FA ratio and serum LDL-C concentrations for sows at weaning were observed. In addition, a positive correlation between omega-6:omega-3 FA in the diet and ADG in piglets was also observed. In conclusion, inclusion of omega-6:omega-3 FA at different ratios in different proportions did not affect sow performance, while increasing HDL-C and tending to reduce LDL-C in serum lipids. However, the piglets born to sows fed 10:1 diets benefitted, with increased BW and ADG.

scholarly journals Omega-3 polyunsaturated fatty acids-enriched hen eggs consumption enhances microvascular reactivity in young healthy individuals

2018 ◽  
Vol 43 (10) ◽  
pp. 988-995 ◽  
Author(s):  
Ana Stupin ◽  
Lidija Rasic ◽  
Anita Matic ◽  
Marko Stupin ◽  
Zlata Kralik ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Lipid Profile ◽  
Serum Lipid ◽  
Serum Lipid Profile ◽  
Control Group ◽  
Omega 3 ◽  
Healthy Individuals ◽  
Microvascular Reactivity ◽  
Significant Difference

The beneficial effect of omega-3 polyunsaturated fatty acids (PUFA) supplementation on the cardiovascular (CV) system is well supported in CV patients; however, the effect of the consumption of omega-3 PUFA-enriched functional food in healthy individuals is still not fully elucidated. This study aimed to determine the effect of the consumption of omega-3 PUFA-enriched hen eggs on the microvascular reactivity (primary outcome), blood pressure (BP), and serum lipid profile in young healthy individuals. The control group (N = 16) ate 3 ordinary hen eggs (277 mg of omega-3 PUFAs/day), and the OMEGA-3 group (N = 20) ate 3 omega-3 PUFA-enriched eggs containing 259 mg of omega-3 PUFAs/egg daily (α-linolenic acid (ALA), 167 mg/egg; eicosapentaenoic acid (EPA), 7 mg/egg; docosahexaenoic acid (DHA), 84 mg/egg) for 3 weeks (777 mg of omega-3 PUFA/day). Postocclusive reactive hyperemia (PORH) in skin microcirculation assessed by laser Doppler flowmetry, serum lipid profile, fasting blood glucose, high-sensitivity C-reactive protein (hsCRP), and arterial BP were measured in all subjects before and after the protocol. PORH was significantly enhanced, and triglycerides, hsCRP, and BP were significantly decreased in the OMEGA-3 group compared with baseline measurements, whereas there was no significant difference in the control group after the protocol when compared with baseline. To the best of our knowledge, this is the first study to demonstrate that consumption of a mixture of omega-3 PUFA (ALA + EPA + DHA), provided via enriched hen eggs, elicits changes in the microvascular reactivity, BP, and triglyceride level in healthy subjects that are associated with CV benefits, thus suggesting that daily consumption of omega-3 PUFA-enriched eggs in healthy individuals may potentially contribute to CV risk factor attenuation and disease prevention.

scholarly journals Effect of Cholesterol and Niacin Supplementation on Serum Lipid Profile in Experimentally Induced Renal Dysfunction in Wistar Rats

2019 ◽  
Vol 8 (8) ◽  
pp. 1019-1028
Author(s):  
Pallavi Khajuria Pratiksha Raghuwanshi ◽  
Aditi Lal Koul Ankur Rastogi ◽  
Dibyendu Chakarborty Vishav Pratap Singh ◽  
Sumeet Kour V.S. Wazir
Keyword(s):  
Lipid Profile ◽  
Renal Dysfunction ◽  
Serum Lipid ◽  
Wistar Rats ◽  
Serum Lipid Profile ◽  
Experimentally Induced

Preparations from purple carrots containing anthocyanins improved intestine microbial activity, serum lipid profile and antioxidant status in rats

2019 ◽  
Vol 60 ◽  
pp. 103442 ◽  
Author(s):  
Ewa Żary-Sikorska ◽  
Bartosz Fotschki ◽  
Joanna Fotschki ◽  
Wiesław Wiczkowski ◽  
Jerzy Juśkiewicz
Keyword(s):  
Lipid Profile ◽  
Microbial Activity ◽  
Serum Lipid ◽  
Antioxidant Status ◽  
Serum Lipid Profile

Serum lipid and electrolyte profiles of Wistar rats fed with Vernonia amygdalina supplemented Vigna subterranea (Bambara groundnut) pudding

2020 ◽  
Vol 3 ◽  
pp. 40-45
Author(s):  
Godwin E. Egbung ◽  
Nyakno A. Essien ◽  
John E. Mgbang ◽  
Josephine E. Egbung
Keyword(s):  
Lipid Profile ◽  
Normal Control ◽  
Serum Lipid ◽  
Wistar Rats ◽  
Total Cholesterol Level ◽  
Bambara Groundnut ◽  
The Body ◽  
Serum Lipid Profile ◽  
Vernonia Amygdalina ◽  
Group 2

Objective: This study investigated the effects of Vernonia amygdalina supplementation on Vigna subterrenea (bambara groundnut) pudding on serum lipid profile and electrolyte levels in Wistar rats. Materials and Methods: Twenty five weanling rats were randomly selected into 5 groups of 5 rats each. Group 1 received normal rat pellet. Groups 2 and 3 received 10% and 5% (w/w) non supplemented bambara pudding, respectively. Groups 4 and 5 were fed with 10% and 5% (w/w) Vernonia supplemented bambara pudding, respectively, for 21 days. The animals were sacrificed using anaesthesia at the end of the experiment and blood sample collected for serum lipid profile and serum electrolyte determinations using standard methods. Results: There was a significant increase (p<0.05) in total cholesterol level in groups 2 (1.64 ± 0.01 mmol/L) and 4 (1.66 ± 0.01 mmol/L) compared to normal control (1.31 ± 0.02 mmol/L). Triacylglycerol level increased significantly in groups 2, 3, and 4 compared to normal control. The high density lipoprotein cholesterol (HDL-c) and Serum sodium level were significantly increased (p < 0.05) in group 2 and 4 respectively compared to the normal control. Potassium, chloride, bicarbonate and calcium levels showed significant increases in group 2 relative to normal control. Phosphate level decreased significantly in group 2 (1.37 ± 0.03 mmol/L), 3 (1.43 ± 0.03 mmol/L) and 5 (1.37 ± 0.03 mmol/L) when compared to normal control (1.75 ± 0.03 mmol/L) respectively. Conclusion: Consumption of bambara groundnut pudding supplemented with Vernonia leaves increases HDL-c level as well as supply appreciable amounts of electrolytes in the body.

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