Isolation and anti-inflammatory effect of astragalin synthesized by enzymatic hydrolysis of tea seed extract

2011 ◽  
Vol 91 (13) ◽  
pp. 2315-2321 ◽  
Author(s):  
Hyang-Bok Lee ◽  
Eun-Ki Kim ◽  
Sang-Jae Park ◽  
Sang-gu Bang ◽  
Tae Gil Kim ◽  
...  
2010 ◽  
Vol 58 (8) ◽  
pp. 4808-4813 ◽  
Author(s):  
Hyang-Bok Lee ◽  
Eun-Ki Kim ◽  
Sang-Jae Park ◽  
Sang-gu Bang ◽  
Tae Gil Kim ◽  
...  

2010 ◽  
Vol 15 (Number 2) ◽  
pp. 19-23
Author(s):  
S Parveen ◽  
Z A Begum

The study was done to find out the anti-inflammatory effects of the ethanolic extract of ground seeds of Nigella swim in inflammed rats. The effect was compared with reference standard drugs aspirin and hydrocortisone. Chronic it was induced by implantation of a sterile cotton pellet in rut's groin region. Treatment with Nigella saliva extract at a dose of 250 mg/kg body weight and at a dose of 500 mg/kg body weight orally daily for 14 days produced anti-inflammatory effect. The percentage of inhibition of granuloma formation were 19.30% and 41.42% respectively. Administration of aspirin and hydrocortisone for 14 days showed also anti-inflanunatoq effect and the percentage of inhibition of granuloma formation were 27.67% and 38.58% respectively.


2020 ◽  
Vol 12 (6) ◽  
pp. 777
Author(s):  
MohammadJamshed Siddiqui ◽  
Adeel Aslam ◽  
Ahmed Nokhala ◽  
Sohaib Peerzada ◽  
Shoaib Ahmed ◽  
...  

Molecules ◽  
2019 ◽  
Vol 24 (10) ◽  
pp. 1938 ◽  
Author(s):  
Hye Soo Wang ◽  
Yoon Jeong Hwang ◽  
Jun Yin ◽  
Min Won Lee

Alnus sibirica (AS) is geographically distributed in Korea, Japan, Northeast China, and Russia. Various anti-oxidant, anti-inflammation, anti-atopic dermatitis and anti-cancer biological effects of AS have been reported. Enzymatic hydrolysis decomposes the sugar bond attached to glycoside into aglycone which, generally, has a superior biological activity, compared to glycoside. Enzymatic hydrolysis of the extract (EAS) from AS was processed and the isolated compounds were investigated—hirsutanonol (1), hirsutenone (2), rubranol (3), and muricarpon B (4). The structures of these compounds were elucidated, and the biological activities were assessed. The ability of EAS and the compounds (1–4) to scavenge 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals and Nitroblue tetrazolium (NBT) superoxide, and to inhibit NO production was evaluated in vitro. EAS showed more potent antioxidant and anti-inflammatory activity than AS. All investigated compounds showed excellent antioxidant and anti-inflammatory activities.


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