Analysis of low molecular weight plant phenolics by thermospray liquid chromatography/mass spectrometry

1992 ◽  
Vol 59 (3) ◽  
pp. 401-404 ◽  
Author(s):  
Guido C Galletti ◽  
John Eagles ◽  
F Alfred Mellon
Keyword(s):  
Mass Spectrometry ◽  
Molecular Weight ◽  
Liquid Chromatography ◽  
Low Molecular Weight ◽  
Plant Phenolics ◽  
Liquid Chromatography Mass Spectrometry ◽  
Chromatography Mass Spectrometry

Analysis of Selected Chemical Groups by Liquid Chromatography/Mass Spectrometry

1993 ◽  
Vol 47 (6) ◽  
pp. 821-829 ◽  
Author(s):  
Kenneth J. Krost
Keyword(s):  
Mass Spectrometry ◽  
Molecular Weight ◽  
Liquid Chromatography ◽  
Limit Of Detection ◽  
Liquid Chromatography Mass Spectrometry ◽  
Chromatography Mass Spectrometry ◽  
Present Technique ◽  
Selective Ion Monitoring ◽  
Full Scan ◽  
Chemical Groups

The use of a moving-belt liquid chromatography/mass spectrometry interface for identifying selected members of various chemical classes has been investigated. Among the chemical groups examined with this system were benzidines, nitrosoamines, anilines, nitroaromatics, dinitroaromatics, hydrazines, amides, phenylenediamines, organophosphites, acrylates, pyridines, phthalates, nitrophenols, halogenated triazines, pesticides, halogenated pyridines, and alkyl tins. Selective ion monitoring was used for detection in all cases, in view of the lack of sensitivity in the full-scan mode. The lower limit of detection for the present technique is approximately 10 nanograms of compounds. Compounds of molecular weight exceeding 250 amu generally show a diminished response. Presumably, some lower-molecular-weight compounds within given groups exhibit similar behavior because of volatilization losses in the inlet.

Sensitive analysis of multiple low-molecular-weight thiols in a single human cervical cancer cell by chemical derivatization-liquid chromatography-mass spectrometry

The Analyst ◽  
2019 ◽  
Vol 144 (22) ◽  
pp. 6578-6585 ◽  
Author(s):  
Hua-Ming Xiao ◽  
Xian Wang ◽  
Quan-Lan Liao ◽  
Shuai Zhao ◽  
Wei-Hua Huang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Cervical Cancer ◽  
Molecular Weight ◽  
Liquid Chromatography ◽  
Low Molecular Weight ◽  
Chemical Derivatization ◽  
Liquid Chromatography Mass Spectrometry ◽  
Simultaneous Quantification ◽  
Human Cervical Cancer Cell ◽  
Human Cervical Cancer

Simultaneous quantification of multiple low-molecular-weight thiols from a single HeLa cell was realized by chemical derivatization assisted LC-MS method.

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