Inhibition of digestive enzymes by condensed tannins from green and ripe carobs

1969 ◽  
Vol 20 (4) ◽  
pp. 199-202 ◽  
Author(s):  
Musha Tamir ◽  
Eugenia Alumot
Keyword(s):  
Condensed Tannins ◽  
Digestive Enzymes

scholarly journals Effects of condensed tannins prepared from leaves of fodder plants on digestive enzymes in vitro and in the intestine of rats

1988 ◽  
Vol 60 (2) ◽  
pp. 275-285 ◽  
Author(s):  
T. Horigome ◽  
R. Kumar ◽  
K. Okamoto
Keyword(s):  
Condensed Tannins ◽  
Digestive Enzymes ◽  
Black Locust ◽  
Inhibitory Effect ◽  
Middle Part ◽  
Degree Of Polymerization ◽  
Molecular Forms ◽  
Reynoutria Japonica ◽  
Fodder Plants

1. Of the nineteen plants screened, six were found to contain large quantities of condensed tannins. Black locust (Robinia pseudo-Acacia), bush clover (Lespedeza bicolor), wistaria (Wistaria floribunda) and Japanese knotgrass (Reynoutria japonica) were used for the present experiment. Tannins of the investigated plants were fractionated into three or four molecular forms, according to the degree of polymerization, by chromatography on a column of Sephadex LH-20.2. The protein-precipitating capacity of the fractionated tannins increased with the increase in degree of polymerization. The inhibitory effect of tannins on trypsin (EC 3.4.21.4), a-amylase (EC 3.2.1.1) and lipase (EC 3.1.1.3) activities in vitro also increased with the increase in degree of polymerization. The digestion of tannin-bovine serum albumin complex by trypsin was related to the degree of polymerization of tannins complexed.3. Inclusion of black locust tannins in the diet (10 g/kg) depressed the activities of trypsin and α-amylase in the upper, middle and lower parts of the intestine of the rats, but the lipase activity was increased in the middle part and remained unaffected in the upper and lower parts. It is presumed that the tannins have little affinity for lipase.4. Digestion trials, when the microflora level of the alimentary canal of rats was reduced by dietary antibiotic treatment, revealed that the inclusion of tannins in the diet (20 g/kg) depressed the digestibilities of proximate constituents, except crude fat, and increased faecal bile acid excretion.

Inhibitory effects of bioaccessible anthocyanins and procyanidins from apple, red grape, cinnamon on α-amylase, α-glucosidase and lipase

2020 ◽  
pp. 1-9
Author(s):  
Pınar Ercan ◽  
Sedef Nehir El
Keyword(s):  
Inhibitory Activity ◽  
Digestive Enzymes ◽  
Positive Control ◽  
Anthocyanin Content ◽  
Inhibitory Effects ◽  
Total Anthocyanin ◽  
Total Anthocyanin Content ◽  
Before And After ◽  
Red Grape

Abstract. The goals of this study were to determine and evaluate the bioaccessibility of total anthocyanin and procyanidin in apple (Amasya, Malus communis), red grape (Papazkarası, Vitis vinifera) and cinnamon (Cassia, Cinnamomum) using an in vitro static digestion system based on human gastrointestinal physiologically relevant conditions. Also, in vitro inhibitory effects of these foods on lipid (lipase) and carbohydrate digestive enzymes (α-amylase and α-glucosidase) were performed with before and after digested samples using acarbose and methylumbelliferyl oleate (4MUO) as the positive control. While the highest total anthocyanin content was found in red grape (164 ± 2.51 mg/100 g), the highest procyanidin content was found in cinnamon (6432 ± 177.31 mg/100 g) (p < 0.05). The anthocyanin bioaccessibilities were found as 10.2 ± 1%, 8.23 ± 0.64%, and 8.73 ± 0.70% in apple, red grape, and cinnamon, respectively. The procyanidin bioaccessibilities of apple, red grape, and cinnamon were found as 17.57 ± 0.71%, 14.08 ± 0.74% and 18.75 ± 1.49%, respectively. The analyzed apple, red grape and cinnamon showed the inhibitory activity against α-glucosidase (IC50 544 ± 21.94, 445 ± 15.67, 1592 ± 17.58 μg/mL, respectively), α-amylase (IC50 38.4 ± 7.26, 56.1 ± 3.60, 3.54 ± 0.86 μg/mL, respectively), and lipase (IC50 52.7 ± 2.05, 581 ± 54.14, 49.6 ± 2.72 μg/mL), respectively. According to our results apple, red grape and cinnamon have potential to inhibit of lipase, α-amylase and α-glucosidase digestive enzymes.

ACTIVITY OF DIGESTIVE ENZYMES IN DUODENAL CHYMUS AND BLOOD IN BROILERS OF PARENTAL LINES AND THE MEAT CROSS DEPENDING ON DIETARY BIOACTIVE ADDITIVES

2017 ◽  
Vol 52 (6) ◽  
pp. 1226-1233
Author(s):  
V.I. Fisinin ◽  
◽  
I.A. Egorov ◽  
V.G. Vertiprakhov ◽  
A.A. Grozina ◽  
...  
Keyword(s):  
Digestive Enzymes ◽  
Parental Lines

Enterogastric Reflux: an Uncommon Diagnosis Analyzed by Hepatobiliary Imaging

2019 ◽  
Vol 8 (2) ◽  
Author(s):  
Peter Wang
Keyword(s):  
Abdominal Pain ◽  
Digestive Enzymes ◽  
Gallbladder Disease ◽  
Hepatobiliary Scintigraphy ◽  
Hepatobiliary Imaging ◽  
Upper Gi ◽  
Gi Symptoms ◽  
Upper Abdominal ◽  
Enterogastric Reflux

Enterogastric reflux (EGR) is the reflux of bile and digestive enzymes from the small bowel into the stomach. While it is a normal physiologic process in small amounts, excessive reflux and chronic EGR can cause upper GI symptoms often mimicking more common diseases such as gallbladder disease and GERD that often leads to its underdiagnosis. Identifying EGR is significant as it has been associated with the development of gastroesophogeal pathology including gastritis, esophagitis, ulcers, and mucosal metaplasia. This article presents a 22-year-old male with enterogastric reflux causing upper abdominal pain and will discuss the role of hepatobiliary scintigraphy in its diagnosis.

Effect of resistance selection on activities of detoxification enzymes and digestive enzymes in Plutella xylostella

2014 ◽  
Vol 39 (5) ◽  
pp. 529-533
Author(s):  
Liu YANG ◽  
Shuang-qing LIU ◽  
Li-jun GONG ◽  
Hui-chao ZHANG ◽  
Ji-Cai TAN ◽  
...  
Keyword(s):  
Plutella Xylostella ◽  
Digestive Enzymes ◽  
Detoxification Enzymes ◽  
Resistance Selection

scholarly journals Impact of starvation on digestive enzymes activities and plasma metabolites in Siberian sturgeon ( Acipenser baerii , Brandt, 1869)

2020 ◽  
Vol 51 (4) ◽  
pp. 1689-1699
Author(s):  
Sedigheh Babaei ◽  
Abdolmohammad Abedian-Kenari ◽  
Mahmood Naseri ◽  
Mohammad Ali Yazdani-Sadati ◽  
Isidoro Metón
Keyword(s):  
Digestive Enzymes ◽  
Siberian Sturgeon ◽  
Plasma Metabolites ◽  
Acipenser Baerii ◽  
Enzymes Activities

scholarly journals Mixing sainfoin and lucerne to improve the feed value of legumes fed to sheep by the effect of condensed tannins

animal ◽  
2013 ◽  
Vol 7 (1) ◽  
pp. 82-92 ◽  
Author(s):  
J. Aufrère ◽  
M. Dudilieu ◽  
D. Andueza ◽  
C. Poncet ◽  
R. Baumont
Keyword(s):  
Condensed Tannins ◽  
Feed Value
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