Tall oil: Isolation of the branched-chain fatty acid (+)-14-methylhexadecanoic acid and of the straight-chain acid palmitic acid

1957 ◽  
Vol 8 (8) ◽  
pp. 482-485 ◽  
Author(s):  
R. P. Hansen ◽  
N. June Cooke
Keyword(s):  
Fatty Acid ◽  
Palmitic Acid ◽  
Chain Fatty Acid ◽  
Straight Chain ◽  
Tall Oil ◽  
Branched Chain ◽  
Straight Chain Acid

scholarly journals In vivo analysis of straight-chain and branched-chain fatty acid biosynthesis in three actinomycetes

1995 ◽  
Vol 131 (2) ◽  
pp. 227-234 ◽  
Author(s):  
Kimberlee K. Wallace ◽  
Bitao Zhao ◽  
Hamish A.I. McArthur ◽  
Kevin A. Reynolds
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Biosynthesis ◽  
Chain Fatty Acid ◽  
Acid Biosynthesis ◽  
Straight Chain ◽  
In Vivo Analysis ◽  
Branched Chain

Expression of fatty acid binding proteins inhibits lipid accumulation and alters toxicity in L cell fibroblasts

2002 ◽  
Vol 283 (3) ◽  
pp. C688-C703 ◽  
Author(s):  
Barbara P. Atshaves ◽  
Stephen M. Storey ◽  
Anca Petrescu ◽  
Cynthia C. Greenberg ◽  
Olga I. Lyuksyutova ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Palmitic Acid ◽  
Lipid Accumulation ◽  
Phytanic Acid ◽  
Chain Fatty Acid ◽  
Fatty Acid Binding Proteins ◽  
Acid Oxidation ◽  
Fatty Acid Binding ◽  
Branched Chain

High levels of saturated, branched-chain fatty acids are deleterious to cells and animals, resulting in lipid accumulation and cytotoxicity. Although fatty acid binding proteins (FABPs) are thought to be protective, this hypothesis has not previously been examined. Phytanic acid (branched chain, 16-carbon backbone) induced lipid accumulation in L cell fibroblasts similar to that observed with palmitic acid (unbranched, C16): triacylglycerol ≫ free fatty acid > cholesterol > cholesteryl ester ≫ phospholipid. Although expression of sterol carrier protein (SCP)-2, SCP-x, or liver FABP (L-FABP) in transfected L cells reduced [3H]phytanic acid uptake (57–87%) and lipid accumulation (21–27%), nevertheless [3H]phytanic acid oxidation was inhibited (74–100%) and phytanic acid toxicity was enhanced in the order L-FABP ≫ SCP-x > SCP-2. These effects differed markedly from those of [3H]palmitic acid, whose uptake, oxidation, and induction of lipid accumulation were not reduced by L-FABP, SCP-2, or SCP-x expression. Furthermore, these proteins did not enhance the cytotoxicity of palmitic acid. In summary, intracellular FABPs reduce lipid accumulation induced by high levels of branched-chain but not straight-chain saturated fatty acids. These beneficial effects were offset by inhibition of branched-chain fatty acid oxidation that correlated with the enhanced toxicity of high levels of branched-chain fatty acid.

scholarly journals Mitochondrial and peroxisomal beta oxidation of the branched chain fatty acid 2-methylpalmitate in rat liver.

1991 ◽  
Vol 266 (36) ◽  
pp. 24670-24675 ◽  
Author(s):  
G. Vanhove ◽  
P.P. Van Veldhoven ◽  
F. Vanhoutte ◽  
G. Parmentier ◽  
H.J. Eyssen ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Rat Liver ◽  
Chain Fatty Acid ◽  
Beta Oxidation ◽  
Branched Chain

scholarly journals Branched-chain fatty acid composition of human milk and the impact of maternal diet: the Global Exploration of Human Milk (GEHM) Study

2016 ◽  
Vol 105 (1) ◽  
pp. 177-184 ◽  
Author(s):  
Kelly A Dingess ◽  
Christina J Valentine ◽  
Nicholas J Ollberding ◽  
Barbara S Davidson ◽  
Jessica G Woo ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Human Milk ◽  
Acid Composition ◽  
Maternal Diet ◽  
Chain Fatty Acid ◽  
Branched Chain ◽  
The Impact
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