Physico-chemical studies on the application of insecticides to sheep fleece. VII.—The influence of cationic wetting agent-fleece reactions on the stability of emulsions and suspensions

1956 ◽  
Vol 7 (4) ◽  
pp. 281-290 ◽  
Author(s):  
C. C. Addison ◽  
C. G. L. Furmidge
Keyword(s):  
Wetting Agent ◽  
Physico Chemical ◽  
Chemical Studies ◽  
The Stability ◽  
Emulsions And Suspensions

scholarly journals Stability of a 50 mg/mL Ceftazidime Eye-Drops Formulation

2018 ◽  
Vol 3 (4) ◽  
pp. 219-226
Author(s):  
Eric Gautier ◽  
Justine Saillard ◽  
Caroline Deshayes ◽  
Sandy Vrignaud ◽  
Frederic Lagarce ◽  
...  
Keyword(s):  
Ph Monitoring ◽  
Treatment Compliance ◽  
Eye Drops ◽  
Microbial Keratitis ◽  
Physico Chemical ◽  
Chemical Studies ◽  
High Doses ◽  
The Stability ◽  
New Formulation ◽  
Antimicrobial Additive

Abstract Background Microbial keratitis are severe infectionsgenerally linked to risk factors. High-doses antibiotic eye-drops could be required to avoid severe complications. In such cases, hospital pharmacists are in charge of their production given the lack of such formulations on the market. The stability of these antibiotic eye-drops is generally limited to a couple of days and publications generally do not describe addition of microbial preservatives even though it is a European Pharmacopeia requirement. The aim of this study was to describe a new ceftazidime eye-drops formulation at 50 mg/mL with a antimicrobial additive, benzalkonium chloride at 0.04 mg/mL. Methods Physico-chemical studies of this new formulation were performed by a stability indicating HPLC-UV method validated according to ICH standards, osmolality measurements, pH monitoring and visual examinations. Antimicrobial preservative efficacy was evaluated according to the method from the European Pharmacopeia. Results After 75 days at −20 °C followed by 7 days at 4 °C, or after 7 days at 4 °C, the eye-drops were stable. A degradation trend was finally observed at day 14 at 4 °C. Conclusions A new ceftazidime eye-drops formulation is proposed with a stability of 7 days. Outpatients do not need to return to the hospital pharmacy for repeat dispensing, thus possibly improving treatment compliance.

scholarly journals Physico-chemical studies of some aminobenzoic acid hydrazide complexes

2004 ◽  
Vol 69 (4) ◽  
pp. 255-264 ◽  
Author(s):  
Abd El ◽  
Abd El ◽  
Gamel El ◽  
Abd El
Keyword(s):  
Acid Hydrazide ◽  
Conductometric Titration ◽  
Aminobenzoic Acid ◽  
X Ray ◽  
Physico Chemical ◽  
Coordination Process ◽  
Different Temperatures ◽  
Chemical Studies ◽  
The Stability ◽  
Thermal Stability Of

The stability constants and related thermodynamic functions characterizing the formation of divalent Ni, Cu, Zn, Cd and Hg complexes with o- and p-aminobenzoic acid hydrazide were determined potentiometrically at different temperatures. The formations of the complexes are endothermic processes. The formed bonds are mainly electrostatic. Conductometric titration was carried out to determine the stoichiometry and stability of the formed complexes. The structures of complexes were characterized by their IR, 1H-NMR and 13C-NMR spectra, as well as X-ray diffractograms. The coordination process takes place through the carbonyl group and the terminal hydrazinic amino group. The thermal stability of the complexes was followed in the temperature range 20?600 ?C.

Design, synthesis and physico-chemical studies of a Co(II)/Co(III) mixed-valence complex: An experimental and DFT approach.

2021 ◽  
pp. 130384
Author(s):  
Intissar Hamdi ◽  
Noureddine Mhadhbi ◽  
Noureddine Issaoui ◽  
Andreas Roodt ◽  
Mark M. Turnbull ◽  
...  
Keyword(s):  
Mixed Valence ◽  
Design Synthesis ◽  
Physico Chemical ◽  
Chemical Studies ◽  
Mixed Valence Complex

scholarly journals Physico-Chemical Studies on the Skin and Leather of Marine Animals-XI

1954 ◽  
Vol 20 (5) ◽  
pp. 421-430 ◽  
Author(s):  
Toyo-o TAKAHASHI ◽  
Makoto TAKEI
Keyword(s):  
Marine Animals ◽  
Physico Chemical ◽  
Chemical Studies

scholarly journals Stability of Fe-oxide nanoparticles coated with natural organic matter under relevant environmental conditions

2014 ◽  
Vol 70 (12) ◽  
pp. 2040-2046 ◽  
Author(s):  
L. Chekli ◽  
S. Phuntsho ◽  
L. D. Tijing ◽  
J. L. Zhou ◽  
J.-H. Kim ◽  
...  
Keyword(s):  
Organic Matter ◽  
Natural Organic Matter ◽  
Environmental Conditions ◽  
Divalent Cations ◽  
Oxide Nanoparticles ◽  
Fe Oxide ◽  
Coated Nanoparticles ◽  
Aggregation Behaviour ◽  
Physico Chemical ◽  
The Stability

Manufactured nanoparticles (MNPs) are increasingly released into the environment and thus research on their fate and behaviour in complex environmental samples is urgently needed. The fate of MNPs in the aquatic environment will mainly depend on the physico-chemical characteristics of the medium. The presence and concentration of natural organic matter (NOM) will play a significant role on the stability of MNPs by either decreasing or exacerbating the aggregation phenomenon. In this study, we firstly investigated the effect of NOM concentration on the aggregation behaviour of manufactured Fe-oxide nanoparticles. Then, the stability of the coated nanoparticles was assessed under relevant environmental conditions. Flow field-flow fractionation, an emerging method which is gaining popularity in the field of nanotechnology, has been employed and results have been compared to another size-measurement technique to provide increased confidence in the outcomes. Results showed enhanced stability when the nanoparticles are coated with NOM, which was due to electrosteric stabilisation. However, the presence of divalent cations, even at low concentration (i.e. less than 1 mM) was found to induce aggregation of NOM-coated nanoparticles via bridging mechanisms between NOM and Ca2+.

scholarly journals Physico-chemical studies on fraction 1 protein from alfalfa.

1978 ◽  
Vol 42 (8) ◽  
pp. 1553-1558 ◽  
Author(s):  
Hajime NOGUCHI ◽  
Takaichi MAEKAWA ◽  
Shigeki FUJIMOTO ◽  
Ichiro SATAKE ◽  
Masaki SAKAKIBARA
Keyword(s):  
Fraction 1 Protein ◽  
Physico Chemical ◽  
Chemical Studies
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