Raman spectroscopic analysis of breast cancer tissues: identifying differences between normal, invasive ductal carcinoma and ductal carcinomain situ of the breast tissue

2007 ◽  
Vol 38 (10) ◽  
pp. 1345-1351 ◽  
Author(s):  
Shazza Rehman ◽  
Zanyar Movasaghi ◽  
Art T. Tucker ◽  
Simon P. Joel ◽  
Jawwad A. Darr ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Invasive Ductal Carcinoma ◽  
Breast Tissue ◽  
Spectroscopic Analysis ◽  
Ductal Carcinoma ◽  
Ductal Carcinomain Situ ◽  
Raman Spectroscopic ◽  
Carcinomain Situ ◽  
Cancer Tissues ◽  
Raman Spectroscopic Analysis

Raman spectroscopic analysis of ovarian cancer tissues and normal ovarian tissues

Laser Physics ◽  
2019 ◽  
Vol 29 (4) ◽  
pp. 045701 ◽  
Author(s):  
K Viswanathan ◽  
K Soumya ◽  
K Gurusankar ◽  
S Jeyavijayan
Keyword(s):  
Ovarian Cancer ◽  
Spectroscopic Analysis ◽  
Raman Spectroscopic ◽  
Cancer Tissues ◽  
Raman Spectroscopic Analysis

Raman spectroscopic analysis differentiates between breast cancer cell lines

2015 ◽  
Vol 46 (5) ◽  
pp. 421-427 ◽  
Author(s):  
A. C. S. Talari ◽  
C. A. Evans ◽  
I. Holen ◽  
R. E. Coleman ◽  
Ihtesham Ur Rehman
Keyword(s):  
Breast Cancer ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Spectroscopic Analysis ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Raman Spectroscopic ◽  
Raman Spectroscopic Analysis

scholarly journals Ductal CarcinomaIn Situ: What the Pathologist Needs to Know and Why

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Anita Bane
Keyword(s):  
Breast Cancer ◽  
Clinical Decision Making ◽  
Ductal Carcinoma ◽  
Clinical Decision ◽  
Invasive Disease ◽  
Screening Mammography ◽  
Pathology Report ◽  
Ductal Carcinomain Situ ◽  
Carcinomain Situ

Ductal carcinomain situis a proliferation of malignant epithelial cells confined to the ductolobular system of the breast. It is considered a pre-cursor lesion for invasive breast cancer and when identified patients are treated with some combination of surgery, +/− radiation therapy, and +/adjuvant tamoxifen. However, no good biomarkers exist that can predict with accuracy those cases of DCIS destined to progress to invasive disease or once treated those patients that are likely to suffer a recurrence; thus, in the era of screening mammography it seems likely that many patients with DCIS are overtreated. This paper details the parameters that should be included in a pathology report for a case of DClS with some explanations as to their importance for good clinical decision making.

scholarly journals Accessory breast cancer in the inframammary region: a case report and review of the literature

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Yuka Eguchi ◽  
Heiji Yoshinaka ◽  
Naoki Hayashi ◽  
Kazunobu Sueyoshi ◽  
Keiichiro Uchikura ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Invasive Ductal Carcinoma ◽  
Breast Tissue ◽  
Ductal Carcinoma ◽  
Surgical Margin ◽  
Wide Resection ◽  
Axillary Lymph ◽  
Accessory Breast ◽  
Stage Ia

Abstract Background Although a few cases of accessory breast cancer (ABC) have been reported, most were in the axillary region. We encountered an extremely rare case of ABC in the inframammary region (IMR). Case presentation The patient was a 68-year-old postmenopausal woman who had noticed a congenital accessory nipple in her left IMR with slight, occasional discharge 20 years ago. Recently, she noticed a mass under the accessory nipple and visited a nearby clinic; fine-needle aspiration cytology of the mass revealed that it was malignant. She presented to our department 2 weeks after she had noticed the mass. Physical and imaging examinations showed an irregular tumor mass 1.7 × 1.4 × 1.0 cm in size connected to the accessory nipple beneath the left normal breast. Neither distant metastasis nor lymph node swelling was observed. Ultrasound-guided core needle biopsy revealed the mass to be invasive ductal carcinoma. We diagnosed her tumor as ABC in the left IMR; cT1cN0M0: stage IA. Curative wide resection with sentinel node biopsy was performed. Intraoperative evaluation of the frozen section revealed a hot and green ipsilateral axillary lymph node that was free from carcinoma; therefore, nodal dissection was avoided. Histopathological examination including immunochemical staining revealed that the tumor was invasive ductal carcinoma arising from the accessory breast tissue, scirrhous type, 1.7 × 1.4 × 1.0 cm in size, with a solid intraductal component. There was no lymphovascular infiltration, and the surgical margin was 1.5 cm or more. The tumor was estrogen and progesterone receptor-positive, Her2/neu-negative, and had a Ki-67 labeling index of 20%. There was no involvement of the three hot and/or green nodes. The final classification was pT1cN0(sn)M0: stage IA. Letrozole 2.5 mg/day will be administered for 5 years as adjuvant hormonal therapy. Conclusions A cutaneous and/or subcutaneous lesion except for proper breast tissue on the milk line, or mammary ridge from axilla to groin may be an accessory breast tissue. Its serial abnormalities must be worried malignant potential to ductal carcinoma which needs some imaging and pathological examinations for definitive diagnosis and appropriate treatment according to the usual orthotopic breast cancer without delay.

Monitoring of breast cancer patients under pre and post treated conditions using Raman spectroscopic analysis of blood plasma

2019 ◽  
Vol 105 ◽  
pp. 102982 ◽  
Author(s):  
Chithra Krishnamoorthy ◽  
Aruna Prakasarao ◽  
Vijayaraghavan Srinivasan ◽  
Sivarama Prasad G.N. ◽  
Ganesan Singaravelu
Keyword(s):  
Breast Cancer ◽  
Blood Plasma ◽  
Cancer Patients ◽  
Spectroscopic Analysis ◽  
Breast Cancer Patients ◽  
Raman Spectroscopic ◽  
Raman Spectroscopic Analysis

scholarly journals MICRO RAMAN SPECTROSCOPIC ANALYSIS ON BLOOD SERUM SAMPLES OF DUCTAL CARCINOMA PATIENTS

2018 ◽  
Vol 11 (9) ◽  
pp. 176
Author(s):  
Sanoj Varghese ◽  
Ambili Reveendran ◽  
V.senthil Kumar ◽  
Karthikeyan Tm ◽  
Venkiteshan Ranganathan
Keyword(s):  
Raman Spectroscopy ◽  
Clustering Analysis ◽  
Spectroscopic Analysis ◽  
Ductal Carcinoma ◽  
Biochemical Changes ◽  
Raman Shift ◽  
Human Breast ◽  
Serum Samples ◽  
Raman Spectroscopic ◽  
Raman Spectroscopic Analysis

Objective: Identification of biochemical changes in ductal cancer patient’s serum samples using micro Raman spectroscopy.Methods: Micro Raman spectroscopy was used for the identification of Raman shift bands. Data analysis was done using K-means clustering.Results: Micro Raman spectroscopic analysis of human breast cancer patient’s serum samples was done. Biochemicals present in the samples were identified from the peak evaluations. K-means clustering analysis was used to differentiate the biochemicals present in the samples.Conclusion: From the study, we conclude that Raman spectroscopy has the potential to differentiate the biochemical changes occurring in the human body, and the differentiation can be done using K-means clustering.

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