Biliary Excretion and Pharmacokinetics of a Gadolinium Chelate Used as a Liver-Specific Contrast Agent for Magnetic Resonance Imaging in the Rat

1993 ◽  
Vol 82 (8) ◽  
pp. 799-803 ◽  
Author(s):  
Gabriele Schuhmann-Giampieri ◽  
Heribert Schitt-Willich ◽  
Thomas Frenzel
1997 ◽  
Vol 36 (26) ◽  
pp. 6086-6093 ◽  
Author(s):  
J. Platzek ◽  
P. Blaszkiewicz ◽  
H. Gries ◽  
P. Luger ◽  
G. Michl ◽  
...  

2007 ◽  
Vol 48 (2) ◽  
pp. 145-149 ◽  
Author(s):  
J. M. MØller ◽  
E. Santoni-Rugiu ◽  
E. Chabanova ◽  
V. Løgager ◽  
A. B. Hansen ◽  
...  

1990 ◽  
Vol 25 (5) ◽  
pp. 545-551 ◽  
Author(s):  
MICHAEL R. NIESMAN ◽  
G. G. BACIC ◽  
S. M. WRIGHT ◽  
H. M. SWARTZ ◽  
R. L. MAGIN

2021 ◽  
Vol 57 (14) ◽  
pp. 1770-1773
Author(s):  
S. A. Amali S. Subasinghe ◽  
Jonathan Romero ◽  
Cassandra L. Ward ◽  
Matthew D. Bailey ◽  
Donna R. Zehner ◽  
...  

The complexes described here serve as contrast agents for magnetic resonance imaging thermometry.


2021 ◽  
Vol 20 ◽  
pp. 153303382110365
Author(s):  
Lin Qiu ◽  
Shuwen Zhou ◽  
Ying Li ◽  
Wen Rui ◽  
Pengfei Cui ◽  
...  

Bifunctional magnetic/fluorescent core-shell silica nanospheres (MNPs) encapsulated with the magnetic Fe3O4 core and a derivate of 8-amimoquinoline (N-(quinolin-8-yl)-2-(3-(triethoxysilyl) propylamino) acetamide) (QTEPA) into the shell were synthesized. These functional MNPs were prepared with a modified stöber method and the formed Fe3O4@SiO2-QTEPA core-shell nanocomposites are biocompatible, water-dispersible, and stable. These prepared nanoparticles were characterized by X-ray power diffraction (XRD), transmission electron microscopy (TEM), thermoelectric plasma Quad II inductively coupled plasma mass spectrometry (ICP-MS), superconducting quantum interference device (SQUID), TG/DTA thermal analyzer (TGA) and Fourier transform infrared spectroscopy (FTIR). Further application of the nanoparticles in detecting Zn2+ was confirmed by the fluorescence experiment: the nanosensor shows high selectivity and sensitivity to Zn2+ with a 22-fold fluorescence emission enhancement in the presence of 10 μM Zn2+. Moreover, the transverse relaxivity measurements show that the core-shell MNPs have T2 relaxivity (r2) of 155.05 mM−1 S−1 based on Fe concentration on the 3.0 T scanner, suggesting that the compound can be used as a negative contrast agent for MRI. Further in vivo experiments showed that these MNPs could be used as MRI contrast agent. Therefore, the new nanosensor provides the dual modality of magnetic resonance imaging and optical imaging.


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