Mechanism of Nasal Absorption of Drugs I: Physicochemical Parameters Influencing the Rate of In Situ Nasal Absorption of Drugs in Rats

1985 ◽  
Vol 74 (6) ◽  
pp. 608-611 ◽  
Author(s):  
Chong Heng Huang ◽  
Ryohei Kimura ◽  
Rima Bawarshi Nassar ◽  
Anwar Hussain
2018 ◽  
Vol 72 (8) ◽  
pp. 1234-1243 ◽  
Author(s):  
Shichuan Xi ◽  
Xin Zhang ◽  
Zhendong Luan ◽  
Zengfeng Du ◽  
Lianfu Li ◽  
...  

Raman spectroscopy has been applied to the quantitative analysis of the concentration of bisulfate in acid-sulfate fluids at different temperatures. The quantitative analysis method is based on the peak area ratios of [Formula: see text](ν1) and H2O (ν2), where PA([Formula: see text]/H2O) = [[Formula: see text]] × (0.0066 × T + 1.3070) at a temperature range of 0–100 ℃. We found that the molal scattering coefficient of bisulfate increases slightly at the elevated temperature may be due to the changes of fraction of water molecules that are hydrogen-bonded. The method can also be applied to analyze physicochemical parameters of other acid fluids, such as hydrogen phosphate, bicarbonate, etc., and especially to the in situ detection of deep sea acid-sulfate hydrothermal fluids in the future.


Nano Today ◽  
2020 ◽  
Vol 35 ◽  
pp. 100932
Author(s):  
Wei Li ◽  
Ming Li ◽  
Xueqing Wang ◽  
Pengcheng Xu ◽  
Haitao Yu ◽  
...  

2010 ◽  
Vol 33 (5) ◽  
pp. 691-696 ◽  
Author(s):  
Yang Lu ◽  
Xiaolan Chen ◽  
Shouying Du ◽  
Qing Wu ◽  
Zongling Yao ◽  
...  

Author(s):  
BRIAN GIL S. SARINAS ◽  
LORNA D. GELLADA ◽  
MELCHOR M. MAGRAMO ◽  
MARLON R. TERUÑEZ

Jetty Port (Parola Wharf) in Iloilo City is a depot of passengers going toGuimaras, Philippines. Considering the dearth of studies on the presence of heavymetals in this area, this study was conducted. It aimed to determine the presenceand quantities of available heavy metals specifically lead, cadmium and chromiumin the water column (surface, middle and bottom) of Iloilo-Guimaras Jetty Port. Inaddition, water physicochemical parameters were also measured such as pH, salinityand temperature, in situ. Three sampling areas were identified in the Jetty Port.One liter was collected in the surface, middle and bottom layer of each sampling area for a total of nine seawater samples. The seawater samples were immediatelytransported to the CAS-Analytical Service Laboratory of UPV, Miag-ao, Iloilofor the quantification of available heavy metals through flame atomic absorptionspectrophotometric (FAAS) method. Ph values range from 6.0-7.333, 12.0-13.167ppm for salinity and 27.333-27.567 0C for three sampling areas. Average cadmium,chromium and lead were higher at station 3 with 0.69 mg/L, 0.81 mg/L and 0.339mg/L, respectively. The results showed that mean of Cr > Pb > Cd < Cr in the watercolumn of the three sampling areas, however is not significant, p>.05. Availablecadmium, chromium and lead exceeded the permissive value. This study will giveinformation to the public about the present heavy metal status of the Jetty Port.


2020 ◽  
Vol 27 (1) ◽  
pp. 95-111
Author(s):  
Joanna Potapowicz ◽  
Danuta Szumińska ◽  
Małgorzata Szopińska ◽  
Sebastian Czapiewski ◽  
Żaneta Polkowska

AbstractIn the present study, the creeks and lakes located at the western shore of Admiralty Bay were analysed. The impact of various sources of water supply was considered, based on the parameters of temperature, pH and specific electrolytic conductivity (SEC25). All measurements were conducted during a field campaign in January–February 2017. A multivariate dataset was also created and a biplot of SEC25 and pH of the investigated waters was performed. The average temperatures of the investigated waters were 0.10-8.10 °C. The pH values indicate that most of the water environments of the analysed area are slightly acidic to alkaline (5.26–8.50) with two exceptions: Siodlo II Creek (9.26) and Petrified Forest Creek (8.95), which are characterised by greater alkalinity. At the measurement points closest to the Baranowski Glacier and Ecology Glacier, SEC25 values were the lowest (26.8–61.1 µS·cm–1), while the remaining values ranged from 79.0 to 382 µS·cm–1 for the whole studied area. Based on the results it is concluded that the periodic intensive inflow of ablation waters, combined with morphological changes in the glacier front, causes a significant variability in the outflow network, creating the conditions for changes in basic physicochemical parameters. Moreover, it is observed that local depressions in the terrain form sedimentation traps in which, alongside fine-grained deposits, compounds can accumulate that originate from in situ sedimentation and that are also associated with surface runoff from the melting of snow cover, buried ice and permafrost.


Author(s):  
MEL Hayo Vianney ◽  
OUFFOUE Koffi Sébastien ◽  
BAMBA Kafoumba ◽  
ZOAKOUMA Roger Simplice Pépin ◽  
DIABAGATE Dangui ◽  
...  

Aims: The aim of this work is to know the interrelationships of the physicochemical parameters likely to explain algal blooms and to identify the potential structures of molecules that can be secreted in an Ivorian lagoon environment: the Ebrié lagoon. Methodology: Nine stations, selected according to natural influences and anthropogenic pressure, were subject to physicochemical monitoring. It consisted of in situ measurements (temperature, salinity, dissolved oxygen, electrical conductivity) and chemical analyses in the laboratory (pH, nitrates, nitrites). In addition to these measurements, observations were noted in the field, namely the climatology of the day, the colour and smell of the water, the presence of algae (micro and / or macroalgae). Results: Our results showed that the waters of the Ebrié lagoon are warm (T > 25 °C), with a pH between 6 and 9 and variable salinity. Salinity would be a discriminating factor for the presence of macroalgae. The nutrients levels (nitrates and nitrites) remain within the limits of acceptability. Conclusion: The waters in our study area are favorable for algal blooms. Given the nuisances associated with algal blooms, the study proposes some structures of toxins which can be secreted on the basis of a literature review.


Data in Brief ◽  
2020 ◽  
Vol 31 ◽  
pp. 106024 ◽  
Author(s):  
Md Masud-Ul-Alam ◽  
Ashif Imam Khan ◽  
Saif Khan Sunny ◽  
Atiqur Rahman ◽  
Muhammad Shahinur Rahman ◽  
...  

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