Amperometric Determination of Hydralazine Hydrochloride in a Flowing Stream at the Glassy Carbon Electrode

1984 ◽  
Vol 73 (7) ◽  
pp. 989-991 ◽  
Author(s):  
Mumtaz H. Shah ◽  
James T. Stewart
Keyword(s):  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Carbon Electrode ◽  
Amperometric Determination ◽  
Hydralazine Hydrochloride ◽  
Flowing Stream

Amperometric Determination of Propantheline Bromide in a Flowing Stream at the Glassy Carbon Electrode

1985 ◽  
Vol 68 (2) ◽  
pp. 165-167
Author(s):  
Mumtaz H Shah ◽  
James T Stewart
Keyword(s):  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Dosage Forms ◽  
Carbon Electrode ◽  
Amperometric Determination ◽  
Pharmaceutical Dosage Forms ◽  
Amperometric Method ◽  
Flowing Stream ◽  
Propantheline Bromide

Abstract University of Georgia, College of Pharmacy, Department of Medicinal Chemistry, Athens, GA 30602 A flow-injection method is presented for the determination of propantheline bromide, based on electrochemical oxidation at the glassy carbon electrode. The amperometric method can determine propantheline bromide in the presence of phenobarbital, commonly found in its combination dosage forms. The procedure is stability-indicating for propantheline when an ether extraction of the dosage form is done before amperometric detection. At the electrode potential of + 1400 mV, the calibration curve is linear in the 2-16 p.g/mL concentration range, and minimum detectability is 20 ng (signal-to-noise ratio of 2). When applied to the analysis of propantheline bromide in selected pharmaceutical dosage forms, the method shows good accuracy and precision. Although automation was not used in this study, the method could readily be incorporated in automated systems because it uses the technique of continuous analysis in a flowing stream

Amperometric Determination of Phenazopyridine Hydrochloride in a Flowing Stream at the Glassy Carbon Electrode

1985 ◽  
Vol 68 (6) ◽  
pp. 1207-1209 ◽  
Author(s):  
Fathalla Belal
Keyword(s):  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Reference Electrode ◽  
Dosage Forms ◽  
Automated System ◽  
Carbon Electrode ◽  
Amperometric Determination ◽  
Pharmaceutical Dosage Forms ◽  
Flowing Stream

Abstract A flow-injection method is described for the determination of phenazopyridine hydrochloride, based on electrochemical oxidation at the glassy carbon electrode. The suggested method is highly specific and can be used to determine phenazopyridine HC1 in the presence of most drugs commonly found in pharmaceutical dosage forms or administered therapeutically. Applying a constant potential of +950 mV vs Ag/AgCl/3.5M KCI reference electrode, the calibration curve was linear in the 1-30 μg/mL range, with minimum detectability of 0.2 ng (signal-to-noise ratio 2). Good accuracy and precision were obtained when the method was applied to some dosage forms containing phenazopyridine HC1. Although automation was not used in this study, an automated system could be incorporated because the method uses the technique of continuous analysis in a flowing stream.

Amperometric determination of Myo-inositol using a glassy carbon electrode modified with nanostructured copper sulfide

2020 ◽  
Vol 187 (6) ◽  
Author(s):  
Rajendran Rajaram ◽  
Muniyandi Kiruba ◽  
Chinnathambi Suresh ◽  
Jayaraman Mathiyarasu ◽  
Shanmugam Kumaran ◽  
...  
Keyword(s):  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Copper Sulfide ◽  
Carbon Electrode ◽  
Amperometric Determination ◽  
Nanostructured Copper
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