Lipid–Protein Interactions: Enhancement of Enzyme Activity of L-Glutamic Acid Dehydrogenase by Nonionic Detergents

1976 ◽  
Vol 65 (12) ◽  
pp. 1799-1801 ◽  
Author(s):  
David H. Kempner ◽  
Brian J. Johnson
Keyword(s):  
Enzyme Activity ◽  
Glutamic Acid ◽  
Protein Interactions ◽  
Acid Dehydrogenase ◽  
Lipid Protein Interactions ◽  
Nonionic Detergents

Visualizing signalling by phosphoinositide 3-kinase pathway lipids

2004 ◽  
Vol 32 (2) ◽  
pp. 336-337 ◽  
Author(s):  
G.D. Prestwich
Keyword(s):  
Enzyme Activity ◽  
Protein Interactions ◽  
Phosphoinositide Metabolism ◽  
University Of Utah ◽  
Phosphodiester Hydrolysis ◽  
Phosphoinositide 3 Kinase ◽  
Lipid Protein Interactions ◽  
The University ◽  
Hydroxy Groups

Cells signal through lipids produced by phospholipid and phosphoinositide metabolism that involves three enzymic processes: (i) ester and phosphodiester hydrolysis by phospholipases; (ii) monophosphate hydrolysis by phosphatases; and (iii) phosphorylation of hydroxy groups by kinases. Unregulated enzyme activity correlates with specific pathologies, which are specific targets for therapeutic intervention. Three categories of reagents developed at the University of Utah and at Echelon Biosciences permit monitoring of in vitro enzyme activity and spatiotemporal changes in intracellular lipid concentrations, and identification of lipid–protein interactions.

Effect of cations on the activity of L-glutamic acid dehydrogenase

Life Sciences ◽  
1963 ◽  
Vol 2 (11) ◽  
pp. 834-839 ◽  
Author(s):  
E. Schoffeniels ◽  
R. Gilles
Keyword(s):  
Glutamic Acid ◽  
Acid Dehydrogenase
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