Excipient–Process Interactions and their Impact on Tablet Compaction and Film Coating

2014 ◽  
Vol 103 (11) ◽  
pp. 3666-3674 ◽  
Author(s):  
Preetanshu Pandey ◽  
Dilbir S. Bindra ◽  
Shruti Gour ◽  
Jade Trinh ◽  
David Buckley ◽  
...  
Keyword(s):  
Film Coating ◽  
Tablet Compaction

Formulation and Evaluation of Atenolol and Indapamide SR Matrix Tablets for Treatment of Hypertension

2014 ◽  
Vol 7 (2) ◽  
pp. 2450-2458
Author(s):  
Sarika Pundir ◽  
Ashutosh Badola
Keyword(s):  
Kinetic Studies ◽  
Film Coating ◽  
Matrix Tablets ◽  
Wet Granulation ◽  
Simultaneous Estimation ◽  
Matrix Tablet ◽  
Release Agent ◽  
Disintegration Time ◽  
Weight Variation

In the present study we have formulated (F1 to F6) matrix tablets of atenolol and indapamide for the management of hypertension. As in simultaneous estimation of these drugs it was found that a confined release can be formulated. In the formulation of SR matrix tablet by using different concentration of delayed release agent DCP and pregelatinized starch as disintegrant we prepared tablets by wet granulation method. For sustained release action HPMC polymers were used for film coating. Preformulation studies were performed prior to compression. The compressed SR matrix tablets were evaluated for weight variation, hardness, friability, drug content, disintegration time and in vitro drug release using USP dissolution apparatus type 2 (paddle). It was found that the optimized formulation showed 49.33%, 48.90%, 48.52%, 47.65%, 46.84% and 46.51% release for atenolol in 12 hours respectively. However, indapamide released 49.62%, 49.39%, 48.72%, 48.27%, 47.59% and 47.36% at the end of 12 hr. The IR spectrum study revealed that there is no disturbance in the principal peaks of pure drugs atenolol and indapamide. This confirms the integrity of pure drugs and no incompatibility of them with excipients. The stability studies were carried out for the optimized batch for one months and it showed satisfactory results. The kinetic studies of the formulations revealed that diffusion is the predominant mechanism of drug and release follows Zero-order, Super case II transport.

Film coating of seeds with Bacillus cereus RS87 spores for early plant growth enhancement

2008 ◽  
Vol 54 (10) ◽  
pp. 861-867 ◽  
Author(s):  
Kanchalee Jetiyanon ◽  
Sakchai Wittaya-Areekul ◽  
Pinyupa Plianbangchang
Keyword(s):  
Plant Growth ◽  
Bacillus Cereus ◽  
Plant Height ◽  
Root Length ◽  
Film Coating ◽  
Field Trials ◽  
Growth Enhancement ◽  
Vegetative Cells ◽  
Plant Growth Promoting ◽  
Growth Promoting

The plant growth-promoting rhizobacterium Bacillus cereus RS87 was previously reported to promote plant growth in various crops in both greenhouse and field trials. To apply as a plant growth promoting agent with practical use, it is essential to ease the burden of routine preparation of a fresh suspension of strain RS87 in laboratory. The objectives of this study were to investigate the feasibility of film-coating seeds with B. cereus RS87 spores for early plant growth enhancement and to reveal the indoleacetic acid (IAA) production released from strain RS87. The experiment consisted of the following 5 treatments: nontreated seeds, water-soaked seeds, film-coated seeds, seeds soaked with vegetative cells of strain RS87, and film-coated seeds with strain RS87 spores. Three experiments were conducted separately to assess seed emergence, root length, and plant height. Results showed that both vegetative cells and spores of strain RS87 significantly promoted (P ≤ 0.05) seed emergence, root length and plant height over the control treatments. The strain RS87 also produced IAA. In conclusion, the film coating of seeds with spores of B. cereus RS87 demonstrated early plant growth enhancement as well as seeds using their vegetative cells. IAA released from strain RS87 would be one of the mechanisms for plant growth enhancement.

scholarly journals Development of a technology for polysaccharide-based film coating

2021 ◽  
Vol 640 (5) ◽  
pp. 052022
Author(s):  
C E Beloglazova ◽  
G E Rysmukhambetova ◽  
L V Karpunina ◽  
M V Zabelina
Keyword(s):  
Film Coating

scholarly journals Polydopamine film coating on polyurethane foams as efficient “sunscreen”. Application to photocatalysis under UV irradiation

2021 ◽  
pp. 101618
Author(s):  
Florian Ponzio ◽  
Julien Kelber ◽  
Laura Birba ◽  
Kamal Rekab ◽  
Vincent Ritleng ◽  
...  
Keyword(s):  
Uv Irradiation ◽  
Film Coating ◽  
Polyurethane Foams

scholarly journals Oxidation of boron-titanium thin film coating during cyclic tests on thermal shock

2020 ◽  
Vol 1005 ◽  
pp. 012006
Author(s):  
E E Suslov ◽  
A S Larionov ◽  
S B Kislitsin ◽  
I I Chernov ◽  
M S Staltsov ◽  
...  
Keyword(s):  
Thin Film ◽  
Thermal Shock ◽  
Film Coating ◽  
Cyclic Tests ◽  
Thin Film Coating ◽  
Titanium Thin Film
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