A Novel Sample Selection Strategy by Near-Infrared Spectroscopy-Based High throughput Tablet Tester for Content Uniformity in Early-Phase Pharmaceutical Product Development

2012 ◽  
Vol 101 (7) ◽  
pp. 2502-2511 ◽  
Author(s):  
Zhenqi Shi ◽  
James G. Hermiller ◽  
Thomas Z. Gunter ◽  
Xiaoyu Zhang ◽  
Dave E. Reed
Keyword(s):  
Infrared Spectroscopy ◽  
Product Development ◽  
Near Infrared Spectroscopy ◽  
High Throughput ◽  
Near Infrared ◽  
Sample Selection ◽  
Pharmaceutical Product ◽  
Selection Strategy ◽  
Content Uniformity ◽  
Pharmaceutical Product Development

scholarly journals Detection of Plasmodium falciparum in laboratory-reared and naturally infected wild mosquitoes using near-infrared spectroscopy

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Dari F. Da ◽  
Ruth McCabe ◽  
Bernard M. Somé ◽  
Pedro M. Esperança ◽  
Katarzyna A. Sala ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Infrared Spectroscopy ◽  
Sensitivity And Specificity ◽  
Near Infrared Spectroscopy ◽  
High Throughput ◽  
Near Infrared ◽  
Field Conditions ◽  
Anopheles Coluzzii ◽  
Insect Vectors ◽  
Infection Status

AbstractThere is an urgent need for high throughput, affordable methods of detecting pathogens inside insect vectors to facilitate surveillance. Near-infrared spectroscopy (NIRS) has shown promise to detect arbovirus and malaria in the laboratory but has not been evaluated in field conditions. Here we investigate the ability of NIRS to identify Plasmodium falciparum in Anopheles coluzzii mosquitoes. NIRS models trained on laboratory-reared mosquitoes infected with wild malaria parasites can detect the parasite in comparable mosquitoes with moderate accuracy though fails to detect oocysts or sporozoites in naturally infected field caught mosquitoes. Models trained on field mosquitoes were unable to predict the infection status of other field mosquitoes. Restricting analyses to mosquitoes of uninfectious and highly-infectious status did improve predictions suggesting sensitivity and specificity may be better in mosquitoes with higher numbers of parasites. Detection of infection appears restricted to homogenous groups of mosquitoes diminishing NIRS utility for detecting malaria within mosquitoes.

Near Infrared Spectroscopy for High-Throughput Characterization of Shea Tree (Vitellaria paradoxa) Nut Fat Profiles

2010 ◽  
Vol 58 (13) ◽  
pp. 7811-7819 ◽  
Author(s):  
Fabrice Davrieux ◽  
François Allal ◽  
Georges Piombo ◽  
Bokary Kelly ◽  
John B. Okulo ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
High Throughput ◽  
Near Infrared ◽  
Vitellaria Paradoxa ◽  
Shea Tree

scholarly journals Prospector: A mobile application for portable, high‐throughput near‐infrared spectroscopy phenotyping

tppj ◽  
2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Trevor W. Rife ◽  
Chaney Courtney ◽  
Jenna Hershberger ◽  
Michael Allen Gore ◽  
Mitchell Neilsen ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
High Throughput ◽  
Mobile Application ◽  
Near Infrared
Sign in / Sign up

Export Citation Format

Share Document