Decoupling the Eeffects of Esurface Chemistry and Humidity on Solid-State Hydrolysis of Aspirin in the Presence of Dicalcium Phosphate Dihydrate

2012 ◽  
Vol 101 (4) ◽  
pp. 1496-1507 ◽  
Author(s):  
Andrew M. Cassidy ◽  
Catherine E. Gardner ◽  
Tony Auffret ◽  
Barry Aldous ◽  
William Jones
2015 ◽  
Vol 51 (4) ◽  
pp. 355-361 ◽  
Author(s):  
V. F. Shamrai ◽  
A. E. Karpikhin ◽  
A. Yu. Fedotov ◽  
V. P. Sirotinkin ◽  
S. M. Barinov ◽  
...  

1989 ◽  
Vol 69 (3) ◽  
pp. 689-693 ◽  
Author(s):  
G. W. MORDEN ◽  
G. J. RACZ

The rate of hydrolysis of DCPD to OCP in solutions of different pH values, calcium concentrations and temperatures was studied. Rates of hydrolysis were very slow at pH 6.0, relatively rapid and similar at pH 7.0 and 8.0, much slower at 10 °C than at 20 or 30 °C, and only slightly increased by increasing calcium concentration. Key words: Dicalcium phosphate dihydrate, hydrolysis, pH, temperature, calcium concentration


2012 ◽  
Vol 447 (2) ◽  
pp. 303-305 ◽  
Author(s):  
I. V. Fadeeva ◽  
S. M. Barinov ◽  
D. Ferro ◽  
V. S. Komlev ◽  
L. I. Shvorneva

2020 ◽  
Vol 1010 ◽  
pp. 549-554
Author(s):  
Khairul Anuar Shariff ◽  
Mohamad Hafizi Abu Bakar ◽  
Arief Cahyanto

The aim of this study is to investigate the behavior of osteoclast cells response on dicalcium phosphate dihydrate (DCPD) layer-coated β-TCP granules. β-TCP granules with 300-600 μm were exposed to acidic calcium phosphate solution for 30 mins in order to get 10 mol% DCPD layer-coated β-TCP granular. DCPD free-coated β-TCP granular had used as control specimen. Both specimens were implant in 9 mm of rat calvarial bone defect for 4 weeks. After 4 weeks, the block section of rat calvarial containing specimen were removed for Tatrate-Resistance Acid Phosphatase (TRAP) analysis. Results of TRAP staining reveal that the number of osteoclast cells attached on 10 mol% layer-coated β-TCP granular is higher than DCPD free-coated β-TCP granular. Since remodeling of new bone formation involved simultaneous osteoclast and osteoblast cells response, therefore, the results obtained in this study indicated that the presence of DCPD layer-coated on β-TCP granular helps to improve osteoclast cells response that contribute in stimulating new bone formation.


2016 ◽  
Vol 52 (2) ◽  
pp. 170-175 ◽  
Author(s):  
A. E. Karpikhin ◽  
A. Yu. Fedotov ◽  
V. S. Komlev ◽  
S. M. Barinov ◽  
V. P. Sirotinkin ◽  
...  

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